MNT.H12INVITRO.0.PS.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MNT.H12INVITRO.0.PS.A
Gene (human)	MNT (GeneCards)
Gene synonyms (human)	BHLHD3, ROX
Gene (mouse)	Mnt
Gene synonyms (mouse)	Rox
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	9
Consensus	vCACGTGKb
GC content	65.39%
Information content (bits; total / per base)	10.573 / 1.175
Data sources	ChIP-Seq + HT-SELEX
Aligned words	1000

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	6 (42)	0.899	0.924	0.81	0.851	0.815	0.913	2.587	2.944	225.877	331.42

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.686	0.674	0.594	0.596	0.553	0.559
Non-Methyl HT-SELEX, 2 experiments	best	0.72	0.711	0.608	0.615	0.559	0.569

TF superclass	Basic domains {1} (TFClass)
TF class	Basic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF family	bHLH-ZIP {1.2.6} (TFClass)
TF subfamily	MAD {1.2.6.7} (TFClass)
TFClass ID	TFClass: 1.2.6.7.6
HGNC	HGNC:7188
MGI	MGI:109150
EntrezGene (human)	GeneID:4335 (SSTAR profile)
EntrezGene (mouse)	GeneID:17428 (SSTAR profile)
UniProt ID (human)	MNT_HUMAN
UniProt ID (mouse)	MNT_MOUSE
UniProt AC (human)	Q99583 (TFClass)
UniProt AC (mouse)	O08789 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	6 human, 0 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	MNT.H12INVITRO.0.PS.A.pcm
PWM	MNT.H12INVITRO.0.PS.A.pwm
PFM	MNT.H12INVITRO.0.PS.A.pfm
Alignment	MNT.H12INVITRO.0.PS.A.words.tsv
Threshold to P-value map	MNT.H12INVITRO.0.PS.A.thr
Motif in other formats
JASPAR format	MNT.H12INVITRO.0.PS.A_jaspar_format.txt
MEME format	MNT.H12INVITRO.0.PS.A_meme_format.meme
Transfac format	MNT.H12INVITRO.0.PS.A_transfac_format.txt
Homer format	MNT.H12INVITRO.0.PS.A_homer_format_0.001.txt MNT.H12INVITRO.0.PS.A_homer_format_0.0005.txt MNT.H12INVITRO.0.PS.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	219.0	211.0	408.0	162.0
02	13.0	976.0	10.0	1.0
03	923.0	4.0	70.0	3.0
04	4.0	792.0	17.0	187.0
05	7.0	10.0	980.0	3.0
06	42.0	14.0	5.0	939.0
07	2.0	3.0	972.0	23.0
08	29.0	107.0	632.0	232.0
09	126.0	249.0	425.0	200.0

PFM

	A	C	G	T
01	0.219	0.211	0.408	0.162
02	0.013	0.976	0.01	0.001
03	0.923	0.004	0.07	0.003
04	0.004	0.792	0.017	0.187
05	0.007	0.01	0.98	0.003
06	0.042	0.014	0.005	0.939
07	0.002	0.003	0.972	0.023
08	0.029	0.107	0.632	0.232
09	0.126	0.249	0.425	0.2

PWM

	A	C	G	T
01	-0.131	-0.168	0.487	-0.43
02	-2.839	1.357	-3.066	-4.525
03	1.301	-3.783	-1.255	-3.975
04	-3.783	1.148	-2.598	-0.288
05	-3.362	-3.066	1.361	-3.975
06	-1.75	-2.773	-3.622	1.318
07	-4.213	-3.975	1.353	-2.32
08	-2.103	-0.84	0.923	-0.074
09	-0.678	-0.004	0.528	-0.221

Standard thresholds

P-value	Threshold
0.001	4.423555
0.0005	5.4444
0.0001	7.64419