MotifMLX.H12INVIVO.0.PM.A
Gene (human)MLX
(GeneCards)
Gene synonyms (human)BHLHD13, TCFL4
Gene (mouse)Mlx
Gene synonyms (mouse)Tcfl4
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length9
ConsensusCMYbTGvhh
GC content56.85%
Information content (bits; total / per base)7.642 / 0.849
Data sourcesChIP-Seq + Methyl-HT-SELEX
Aligned words876

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (7) 0.778 0.804 0.684 0.718 0.728 0.76 2.308 2.474 133.602 192.137

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 10 experiments median 0.993 0.988 0.99 0.984 0.981 0.974
best 0.999 0.998 0.997 0.995 0.995 0.991
Methyl HT-SELEX, 3 experiments median 0.993 0.988 0.99 0.983 0.98 0.971
best 0.993 0.988 0.99 0.984 0.985 0.976
Non-Methyl HT-SELEX, 7 experiments median 0.994 0.99 0.991 0.985 0.981 0.977
best 0.999 0.998 0.997 0.995 0.995 0.991

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.751 0.383 0.764 0.578
TF superclassBasic domains {1} (TFClass)
TF classBasic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF familybHLH-ZIP {1.2.6} (TFClass)
TF subfamilyMONDOlike {1.2.6.6} (TFClass)
TFClass IDTFClass: 1.2.6.6.1
HGNCHGNC:11645
MGIMGI:108398
EntrezGene (human)GeneID:6945
(SSTAR profile)
EntrezGene (mouse)GeneID:21428
(SSTAR profile)
UniProt ID (human)MLX_HUMAN
UniProt ID (mouse)MLX_MOUSE
UniProt AC (human)Q9UH92
(TFClass)
UniProt AC (mouse)O08609
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 0 mouse
HT-SELEX 7
Methyl-HT-SELEX 3
PCM
ACGT
0184.0725.018.049.0
02558.0197.071.050.0
0311.0484.024.0357.0
0416.0102.0656.0102.0
055.01.02.0868.0
068.04.0854.010.0
07383.0145.0249.099.0
08179.0340.072.0285.0
09170.0454.084.0168.0
PFM
ACGT
010.0960.8280.0210.056
020.6370.2250.0810.057
030.0130.5530.0270.408
040.0180.1160.7490.116
050.0060.0010.0020.991
060.0090.0050.9750.011
070.4370.1660.2840.113
080.2040.3880.0820.325
090.1940.5180.0960.192
PWM
ACGT
01-0.9461.192-2.416-1.471
020.931-0.105-1.111-1.451
03-2.8560.789-2.1510.486
04-2.524-0.7551.092-0.755
05-3.496-4.406-4.091.371
06-3.125-3.6571.355-2.938
070.556-0.4080.127-0.785
08-0.20.437-1.0970.262
09-0.2510.725-0.946-0.263
Standard thresholds
P-value Threshold
0.001 5.18258
0.0005 5.864705
0.0001 7.020525