MotifMLX.H12INVITRO.1.SM.B
Gene (human)MLX
(GeneCards)
Gene synonyms (human)BHLHD13, TCFL4
Gene (mouse)Mlx
Gene synonyms (mouse)Tcfl4
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length11
ConsensusnCACGTGMhhn
GC content57.01%
Information content (bits; total / per base)12.811 / 1.165
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9417

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (7) 0.768 0.802 0.678 0.727 0.709 0.747 2.378 2.641 164.143 240.252

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 10 experiments median 0.993 0.988 0.987 0.982 0.976 0.961
best 0.999 0.998 0.997 0.994 0.996 0.993
Methyl HT-SELEX, 3 experiments median 0.993 0.988 0.988 0.98 0.985 0.975
best 0.993 0.989 0.99 0.984 0.985 0.976
Non-Methyl HT-SELEX, 7 experiments median 0.995 0.991 0.987 0.986 0.797 0.829
best 0.999 0.998 0.997 0.994 0.996 0.993

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.87 0.624 0.834 0.615
TF superclassBasic domains {1} (TFClass)
TF classBasic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF familybHLH-ZIP {1.2.6} (TFClass)
TF subfamilyMONDOlike {1.2.6.6} (TFClass)
TFClass IDTFClass: 1.2.6.6.1
HGNCHGNC:11645
MGIMGI:108398
EntrezGene (human)GeneID:6945
(SSTAR profile)
EntrezGene (mouse)GeneID:21428
(SSTAR profile)
UniProt ID (human)MLX_HUMAN
UniProt ID (mouse)MLX_MOUSE
UniProt AC (human)Q9UH92
(TFClass)
UniProt AC (mouse)O08609
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 0 mouse
HT-SELEX 7
Methyl-HT-SELEX 3
PCM
ACGT
011618.753106.752349.752341.75
0248.259339.2513.2516.25
039374.04.023.016.0
040.08730.06.0681.0
05120.09.09288.00.0
060.00.00.09417.0
076.09.09357.045.0
086020.02877.0303.0217.0
091221.02741.0432.05023.0
102068.254747.25996.251605.25
112907.752473.752245.751789.75
PFM
ACGT
010.1720.330.250.249
020.0050.9920.0010.002
030.9950.00.0020.002
040.00.9270.0010.072
050.0130.0010.9860.0
060.00.00.01.0
070.0010.0010.9940.005
080.6390.3060.0320.023
090.130.2910.0460.533
100.220.5040.1060.17
110.3090.2630.2380.19
PWM
ACGT
01-0.3740.277-0.002-0.005
02-3.8421.377-5.022-4.845
031.381-5.926-4.535-4.859
04-6.9371.31-5.65-1.238
05-2.959-5.3411.372-6.937
06-6.937-6.937-6.9371.386
07-5.65-5.3411.379-3.909
080.9380.2-2.044-2.375
09-0.6560.152-1.6910.757
10-0.1290.701-0.859-0.382
110.2110.049-0.047-0.274
Standard thresholds
P-value Threshold
0.001 2.55467
0.0005 3.96002
0.0001 7.442815