MIXL1.H12INVITRO.0.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MIXL1.H12INVITRO.0.SM.B
Gene (human)	MIXL1 (GeneCards)
Gene synonyms (human)	MIXL
Gene (mouse)	Mixl1
Gene synonyms (mouse)	Mix, Mml
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	17
Consensus	nvbTAATTARRTTAvbn
GC content	29.59%
Information content (bits; total / per base)	16.575 / 0.975
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	5847

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.981	0.971	0.961	0.946	0.915	0.902
Overall, 4 experiments	best	0.999	0.999	0.999	0.998	0.995	0.993
Methyl HT-SELEX, 1 experiments	median	0.999	0.999	0.999	0.998	0.995	0.993
Methyl HT-SELEX, 1 experiments	best	0.999	0.999	0.999	0.998	0.995	0.993
Non-Methyl HT-SELEX, 3 experiments	median	0.963	0.944	0.925	0.897	0.841	0.819
Non-Methyl HT-SELEX, 3 experiments	best	0.999	0.998	0.997	0.995	0.989	0.985

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.947	0.281	0.911	0.605
batch 2	0.717	0.424	0.69	0.501

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	Paired-related HD {3.1.3} (TFClass)
TF subfamily	MIX {3.1.3.14} (TFClass)
TFClass ID	TFClass: 3.1.3.14.1
HGNC	HGNC:13363
MGI	MGI:1351322
EntrezGene (human)	GeneID:83881 (SSTAR profile)
EntrezGene (mouse)	GeneID:27217 (SSTAR profile)
UniProt ID (human)	MIXL1_HUMAN
UniProt ID (mouse)	MIXL1_MOUSE
UniProt AC (human)	Q9H2W2 (TFClass)
UniProt AC (mouse)	Q9WUI0 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	3
Methyl-HT-SELEX	1

PCM	MIXL1.H12INVITRO.0.SM.B.pcm
PWM	MIXL1.H12INVITRO.0.SM.B.pwm
PFM	MIXL1.H12INVITRO.0.SM.B.pfm
Alignment	MIXL1.H12INVITRO.0.SM.B.words.tsv
Threshold to P-value map	MIXL1.H12INVITRO.0.SM.B.thr
Motif in other formats
JASPAR format	MIXL1.H12INVITRO.0.SM.B_jaspar_format.txt
MEME format	MIXL1.H12INVITRO.0.SM.B_meme_format.meme
Transfac format	MIXL1.H12INVITRO.0.SM.B_transfac_format.txt
Homer format	MIXL1.H12INVITRO.0.SM.B_homer_format_0.001.txt MIXL1.H12INVITRO.0.SM.B_homer_format_0.0005.txt MIXL1.H12INVITRO.0.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1420.0	1836.0	1457.0	1134.0
02	1354.25	1269.25	2707.25	516.25
03	532.0	2144.0	1235.0	1936.0
04	38.0	51.0	12.0	5746.0
05	5772.0	1.0	72.0	2.0
06	5847.0	0.0	0.0	0.0
07	0.0	0.0	0.0	5847.0
08	0.0	131.0	14.0	5702.0
09	4941.0	314.0	592.0	0.0
10	1542.0	611.0	3678.0	16.0
11	4197.0	519.0	844.0	287.0
12	52.0	149.0	364.0	5282.0
13	99.0	814.0	187.0	4747.0
14	5076.0	211.0	319.0	241.0
15	2002.0	1466.0	1687.0	692.0
16	774.25	2281.25	1425.25	1366.25
17	1195.75	1445.75	1575.75	1629.75

PFM

	A	C	G	T
01	0.243	0.314	0.249	0.194
02	0.232	0.217	0.463	0.088
03	0.091	0.367	0.211	0.331
04	0.006	0.009	0.002	0.983
05	0.987	0.0	0.012	0.0
06	1.0	0.0	0.0	0.0
07	0.0	0.0	0.0	1.0
08	0.0	0.022	0.002	0.975
09	0.845	0.054	0.101	0.0
10	0.264	0.104	0.629	0.003
11	0.718	0.089	0.144	0.049
12	0.009	0.025	0.062	0.903
13	0.017	0.139	0.032	0.812
14	0.868	0.036	0.055	0.041
15	0.342	0.251	0.289	0.118
16	0.132	0.39	0.244	0.234
17	0.205	0.247	0.269	0.279

PWM

	A	C	G	T
01	-0.029	0.228	-0.003	-0.253
02	-0.076	-0.141	0.616	-1.038
03	-1.008	0.383	-0.168	0.281
04	-3.596	-3.315	-4.638	1.368
05	1.372	-6.136	-2.983	-5.861
06	1.385	-6.515	-6.515	-6.515
07	-6.515	-6.515	-6.515	1.385
08	-6.515	-2.397	-4.506	1.36
09	1.217	-1.533	-0.902	-6.515
10	0.053	-0.87	0.922	-4.389
11	1.054	-1.033	-0.548	-1.622
12	-3.297	-2.27	-1.386	1.284
13	-2.672	-0.584	-2.046	1.177
14	1.244	-1.927	-1.517	-1.795
15	0.314	0.003	0.143	-0.746
16	-0.634	0.445	-0.025	-0.067
17	-0.201	-0.011	0.075	0.109

Standard thresholds

P-value	Threshold
0.001	1.00046
0.0005	2.57136
0.0001	5.77411