Motif | MIXL1.H12CORE.1.S.B |
Gene (human) | MIXL1 (GeneCards) |
Gene synonyms (human) | MIXL |
Gene (mouse) | Mixl1 |
Gene synonyms (mouse) | Mix, Mml |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 1 |
Quality | B |
Motif | MIXL1.H12CORE.1.S.B |
Gene (human) | MIXL1 (GeneCards) |
Gene synonyms (human) | MIXL |
Gene (mouse) | Mixl1 |
Gene synonyms (mouse) | Mix, Mml |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 1 |
Quality | B |
Motif length | 12 |
Consensus | nnTAATTARnbn |
GC content | 26.12% |
Information content (bits; total / per base) | 11.842 / 0.987 |
Data sources | HT-SELEX |
Aligned words | 8791 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 4 experiments | median | 0.977 | 0.958 | 0.963 | 0.942 | 0.916 | 0.896 |
best | 0.992 | 0.985 | 0.988 | 0.98 | 0.973 | 0.961 | |
Methyl HT-SELEX, 1 experiments | median | 0.986 | 0.972 | 0.981 | 0.967 | 0.966 | 0.949 |
best | 0.986 | 0.972 | 0.981 | 0.967 | 0.966 | 0.949 | |
Non-Methyl HT-SELEX, 3 experiments | median | 0.968 | 0.945 | 0.944 | 0.916 | 0.865 | 0.843 |
best | 0.992 | 0.985 | 0.988 | 0.98 | 0.973 | 0.961 |
rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
---|---|---|---|---|
batch 1 | 0.863 | 0.12 | 0.832 | 0.552 |
batch 2 | 0.702 | 0.385 | 0.662 | 0.501 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Homeo domain factors {3.1} (TFClass) |
TF family | Paired-related HD {3.1.3} (TFClass) |
TF subfamily | MIX {3.1.3.14} (TFClass) |
TFClass ID | TFClass: 3.1.3.14.1 |
HGNC | HGNC:13363 |
MGI | MGI:1351322 |
EntrezGene (human) | GeneID:83881 (SSTAR profile) |
EntrezGene (mouse) | GeneID:27217 (SSTAR profile) |
UniProt ID (human) | MIXL1_HUMAN |
UniProt ID (mouse) | MIXL1_MOUSE |
UniProt AC (human) | Q9H2W2 (TFClass) |
UniProt AC (mouse) | Q9WUI0 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 0 human, 0 mouse |
HT-SELEX | 3 |
Methyl-HT-SELEX | 1 |
PCM | MIXL1.H12CORE.1.S.B.pcm |
PWM | MIXL1.H12CORE.1.S.B.pwm |
PFM | MIXL1.H12CORE.1.S.B.pfm |
Alignment | MIXL1.H12CORE.1.S.B.words.tsv |
Threshold to P-value map | MIXL1.H12CORE.1.S.B.thr |
Motif in other formats | |
JASPAR format | MIXL1.H12CORE.1.S.B_jaspar_format.txt |
MEME format | MIXL1.H12CORE.1.S.B_meme_format.meme |
Transfac format | MIXL1.H12CORE.1.S.B_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 2208.25 | 1869.25 | 1956.25 | 2757.25 |
02 | 1487.75 | 1877.75 | 2267.75 | 3157.75 |
03 | 179.0 | 1426.0 | 149.0 | 7037.0 |
04 | 8266.0 | 51.0 | 473.0 | 1.0 |
05 | 8791.0 | 0.0 | 0.0 | 0.0 |
06 | 0.0 | 0.0 | 0.0 | 8791.0 |
07 | 0.0 | 0.0 | 0.0 | 8791.0 |
08 | 8791.0 | 0.0 | 0.0 | 0.0 |
09 | 3300.0 | 455.0 | 5022.0 | 14.0 |
10 | 1443.0 | 2908.0 | 1521.0 | 2919.0 |
11 | 1076.75 | 1744.75 | 2321.75 | 3647.75 |
12 | 2298.0 | 1887.0 | 1625.0 | 2981.0 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.251 | 0.213 | 0.223 | 0.314 |
02 | 0.169 | 0.214 | 0.258 | 0.359 |
03 | 0.02 | 0.162 | 0.017 | 0.8 |
04 | 0.94 | 0.006 | 0.054 | 0.0 |
05 | 1.0 | 0.0 | 0.0 | 0.0 |
06 | 0.0 | 0.0 | 0.0 | 1.0 |
07 | 0.0 | 0.0 | 0.0 | 1.0 |
08 | 1.0 | 0.0 | 0.0 | 0.0 |
09 | 0.375 | 0.052 | 0.571 | 0.002 |
10 | 0.164 | 0.331 | 0.173 | 0.332 |
11 | 0.122 | 0.198 | 0.264 | 0.415 |
12 | 0.261 | 0.215 | 0.185 | 0.339 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.005 | -0.162 | -0.116 | 0.227 |
02 | -0.39 | -0.157 | 0.031 | 0.362 |
03 | -2.496 | -0.432 | -2.677 | 1.163 |
04 | 1.324 | -3.721 | -1.532 | -6.511 |
05 | 1.386 | -6.876 | -6.876 | -6.876 |
06 | -6.876 | -6.876 | -6.876 | 1.386 |
07 | -6.876 | -6.876 | -6.876 | 1.386 |
08 | 1.386 | -6.876 | -6.876 | -6.876 |
09 | 0.406 | -1.571 | 0.826 | -4.907 |
10 | -0.42 | 0.28 | -0.368 | 0.284 |
11 | -0.712 | -0.231 | 0.055 | 0.506 |
12 | 0.045 | -0.152 | -0.302 | 0.305 |
P-value | Threshold |
---|---|
0.001 | 3.174965 |
0.0005 | 5.02447 |
0.0001 | 7.91768 |