MotifMIXL1.H12CORE.1.S.B
Gene (human)MIXL1
(GeneCards)
Gene synonyms (human)MIXL
Gene (mouse)Mixl1
Gene synonyms (mouse)Mix, Mml
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length12
ConsensusnnTAATTARnbn
GC content26.12%
Information content (bits; total / per base)11.842 / 0.987
Data sourcesHT-SELEX
Aligned words8791

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.977 0.958 0.963 0.942 0.916 0.896
best 0.992 0.985 0.988 0.98 0.973 0.961
Methyl HT-SELEX, 1 experiments median 0.986 0.972 0.981 0.967 0.966 0.949
best 0.986 0.972 0.981 0.967 0.966 0.949
Non-Methyl HT-SELEX, 3 experiments median 0.968 0.945 0.944 0.916 0.865 0.843
best 0.992 0.985 0.988 0.98 0.973 0.961

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.863 0.12 0.832 0.552
batch 2 0.702 0.385 0.662 0.501
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyPaired-related HD {3.1.3} (TFClass)
TF subfamilyMIX {3.1.3.14} (TFClass)
TFClass IDTFClass: 3.1.3.14.1
HGNCHGNC:13363
MGIMGI:1351322
EntrezGene (human)GeneID:83881
(SSTAR profile)
EntrezGene (mouse)GeneID:27217
(SSTAR profile)
UniProt ID (human)MIXL1_HUMAN
UniProt ID (mouse)MIXL1_MOUSE
UniProt AC (human)Q9H2W2
(TFClass)
UniProt AC (mouse)Q9WUI0
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
012208.251869.251956.252757.25
021487.751877.752267.753157.75
03179.01426.0149.07037.0
048266.051.0473.01.0
058791.00.00.00.0
060.00.00.08791.0
070.00.00.08791.0
088791.00.00.00.0
093300.0455.05022.014.0
101443.02908.01521.02919.0
111076.751744.752321.753647.75
122298.01887.01625.02981.0
PFM
ACGT
010.2510.2130.2230.314
020.1690.2140.2580.359
030.020.1620.0170.8
040.940.0060.0540.0
051.00.00.00.0
060.00.00.01.0
070.00.00.01.0
081.00.00.00.0
090.3750.0520.5710.002
100.1640.3310.1730.332
110.1220.1980.2640.415
120.2610.2150.1850.339
PWM
ACGT
010.005-0.162-0.1160.227
02-0.39-0.1570.0310.362
03-2.496-0.432-2.6771.163
041.324-3.721-1.532-6.511
051.386-6.876-6.876-6.876
06-6.876-6.876-6.8761.386
07-6.876-6.876-6.8761.386
081.386-6.876-6.876-6.876
090.406-1.5710.826-4.907
10-0.420.28-0.3680.284
11-0.712-0.2310.0550.506
120.045-0.152-0.3020.305
Standard thresholds
P-value Threshold
0.001 3.174965
0.0005 5.02447
0.0001 7.91768