Motif | MIXL1.H12CORE.0.SM.B |
Gene (human) | MIXL1 (GeneCards) |
Gene synonyms (human) | MIXL |
Gene (mouse) | Mixl1 |
Gene synonyms (mouse) | Mix, Mml |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | B |
Motif | MIXL1.H12CORE.0.SM.B |
Gene (human) | MIXL1 (GeneCards) |
Gene synonyms (human) | MIXL |
Gene (mouse) | Mixl1 |
Gene synonyms (mouse) | Mix, Mml |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | B |
Motif length | 16 |
Consensus | nvbTAATTAGATTAvn |
GC content | 23.7% |
Information content (bits; total / per base) | 19.396 / 1.212 |
Data sources | HT-SELEX + Methyl-HT-SELEX |
Aligned words | 7953 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 4 experiments | median | 0.976 | 0.966 | 0.943 | 0.929 | 0.89 | 0.879 |
best | 0.999 | 0.999 | 0.999 | 0.998 | 0.997 | 0.996 | |
Methyl HT-SELEX, 1 experiments | median | 0.999 | 0.999 | 0.999 | 0.998 | 0.997 | 0.996 |
best | 0.999 | 0.999 | 0.999 | 0.998 | 0.997 | 0.996 | |
Non-Methyl HT-SELEX, 3 experiments | median | 0.953 | 0.933 | 0.889 | 0.861 | 0.792 | 0.773 |
best | 0.999 | 0.998 | 0.998 | 0.996 | 0.988 | 0.985 |
rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
---|---|---|---|---|
batch 1 | 0.951 | 0.379 | 0.946 | 0.656 |
batch 2 | 0.72 | 0.441 | 0.745 | 0.535 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Homeo domain factors {3.1} (TFClass) |
TF family | Paired-related HD {3.1.3} (TFClass) |
TF subfamily | MIX {3.1.3.14} (TFClass) |
TFClass ID | TFClass: 3.1.3.14.1 |
HGNC | HGNC:13363 |
MGI | MGI:1351322 |
EntrezGene (human) | GeneID:83881 (SSTAR profile) |
EntrezGene (mouse) | GeneID:27217 (SSTAR profile) |
UniProt ID (human) | MIXL1_HUMAN |
UniProt ID (mouse) | MIXL1_MOUSE |
UniProt AC (human) | Q9H2W2 (TFClass) |
UniProt AC (mouse) | Q9WUI0 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 0 human, 0 mouse |
HT-SELEX | 3 |
Methyl-HT-SELEX | 1 |
PCM | MIXL1.H12CORE.0.SM.B.pcm |
PWM | MIXL1.H12CORE.0.SM.B.pwm |
PFM | MIXL1.H12CORE.0.SM.B.pfm |
Alignment | MIXL1.H12CORE.0.SM.B.words.tsv |
Threshold to P-value map | MIXL1.H12CORE.0.SM.B.thr |
Motif in other formats | |
JASPAR format | MIXL1.H12CORE.0.SM.B_jaspar_format.txt |
MEME format | MIXL1.H12CORE.0.SM.B_meme_format.meme |
Transfac format | MIXL1.H12CORE.0.SM.B_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 2279.75 | 2228.75 | 1748.75 | 1695.75 |
02 | 1977.5 | 1516.5 | 3440.5 | 1018.5 |
03 | 887.0 | 2687.0 | 1263.0 | 3116.0 |
04 | 58.0 | 56.0 | 13.0 | 7826.0 |
05 | 7762.0 | 2.0 | 185.0 | 4.0 |
06 | 7953.0 | 0.0 | 0.0 | 0.0 |
07 | 0.0 | 10.0 | 0.0 | 7943.0 |
08 | 0.0 | 65.0 | 39.0 | 7849.0 |
09 | 6819.0 | 148.0 | 847.0 | 139.0 |
10 | 1460.0 | 407.0 | 6084.0 | 2.0 |
11 | 7417.0 | 42.0 | 447.0 | 47.0 |
12 | 2.0 | 18.0 | 15.0 | 7918.0 |
13 | 23.0 | 301.0 | 13.0 | 7616.0 |
14 | 7721.0 | 29.0 | 86.0 | 117.0 |
15 | 3037.75 | 1449.75 | 2384.75 | 1080.75 |
16 | 1239.25 | 3007.25 | 1620.25 | 2086.25 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.287 | 0.28 | 0.22 | 0.213 |
02 | 0.249 | 0.191 | 0.433 | 0.128 |
03 | 0.112 | 0.338 | 0.159 | 0.392 |
04 | 0.007 | 0.007 | 0.002 | 0.984 |
05 | 0.976 | 0.0 | 0.023 | 0.001 |
06 | 1.0 | 0.0 | 0.0 | 0.0 |
07 | 0.0 | 0.001 | 0.0 | 0.999 |
08 | 0.0 | 0.008 | 0.005 | 0.987 |
09 | 0.857 | 0.019 | 0.107 | 0.017 |
10 | 0.184 | 0.051 | 0.765 | 0.0 |
11 | 0.933 | 0.005 | 0.056 | 0.006 |
12 | 0.0 | 0.002 | 0.002 | 0.996 |
13 | 0.003 | 0.038 | 0.002 | 0.958 |
14 | 0.971 | 0.004 | 0.011 | 0.015 |
15 | 0.382 | 0.182 | 0.3 | 0.136 |
16 | 0.156 | 0.378 | 0.204 | 0.262 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.137 | 0.114 | -0.128 | -0.159 |
02 | -0.005 | -0.27 | 0.548 | -0.668 |
03 | -0.806 | 0.301 | -0.453 | 0.449 |
04 | -3.498 | -3.531 | -4.872 | 1.369 |
05 | 1.361 | -6.15 | -2.364 | -5.764 |
06 | 1.385 | -6.787 | -6.787 | -6.787 |
07 | -6.787 | -5.091 | -6.787 | 1.384 |
08 | -6.787 | -3.388 | -3.877 | 1.372 |
09 | 1.232 | -2.584 | -0.852 | -2.646 |
10 | -0.308 | -1.582 | 1.118 | -6.15 |
11 | 1.316 | -3.806 | -1.489 | -3.699 |
12 | -6.15 | -4.588 | -4.749 | 1.381 |
13 | -4.367 | -1.882 | -4.872 | 1.342 |
14 | 1.356 | -4.154 | -3.116 | -2.815 |
15 | 0.423 | -0.315 | 0.182 | -0.609 |
16 | -0.472 | 0.413 | -0.204 | 0.048 |
P-value | Threshold |
---|---|
0.001 | -2.06819 |
0.0005 | -0.23934 |
0.0001 | 3.58521 |