MotifMIXL1.H12CORE.0.SM.B
Gene (human)MIXL1
(GeneCards)
Gene synonyms (human)MIXL
Gene (mouse)Mixl1
Gene synonyms (mouse)Mix, Mml
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length16
ConsensusnvbTAATTAGATTAvn
GC content23.7%
Information content (bits; total / per base)19.396 / 1.212
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words7953

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.976 0.966 0.943 0.929 0.89 0.879
best 0.999 0.999 0.999 0.998 0.997 0.996
Methyl HT-SELEX, 1 experiments median 0.999 0.999 0.999 0.998 0.997 0.996
best 0.999 0.999 0.999 0.998 0.997 0.996
Non-Methyl HT-SELEX, 3 experiments median 0.953 0.933 0.889 0.861 0.792 0.773
best 0.999 0.998 0.998 0.996 0.988 0.985

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.951 0.379 0.946 0.656
batch 2 0.72 0.441 0.745 0.535
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyPaired-related HD {3.1.3} (TFClass)
TF subfamilyMIX {3.1.3.14} (TFClass)
TFClass IDTFClass: 3.1.3.14.1
HGNCHGNC:13363
MGIMGI:1351322
EntrezGene (human)GeneID:83881
(SSTAR profile)
EntrezGene (mouse)GeneID:27217
(SSTAR profile)
UniProt ID (human)MIXL1_HUMAN
UniProt ID (mouse)MIXL1_MOUSE
UniProt AC (human)Q9H2W2
(TFClass)
UniProt AC (mouse)Q9WUI0
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
012279.752228.751748.751695.75
021977.51516.53440.51018.5
03887.02687.01263.03116.0
0458.056.013.07826.0
057762.02.0185.04.0
067953.00.00.00.0
070.010.00.07943.0
080.065.039.07849.0
096819.0148.0847.0139.0
101460.0407.06084.02.0
117417.042.0447.047.0
122.018.015.07918.0
1323.0301.013.07616.0
147721.029.086.0117.0
153037.751449.752384.751080.75
161239.253007.251620.252086.25
PFM
ACGT
010.2870.280.220.213
020.2490.1910.4330.128
030.1120.3380.1590.392
040.0070.0070.0020.984
050.9760.00.0230.001
061.00.00.00.0
070.00.0010.00.999
080.00.0080.0050.987
090.8570.0190.1070.017
100.1840.0510.7650.0
110.9330.0050.0560.006
120.00.0020.0020.996
130.0030.0380.0020.958
140.9710.0040.0110.015
150.3820.1820.30.136
160.1560.3780.2040.262
PWM
ACGT
010.1370.114-0.128-0.159
02-0.005-0.270.548-0.668
03-0.8060.301-0.4530.449
04-3.498-3.531-4.8721.369
051.361-6.15-2.364-5.764
061.385-6.787-6.787-6.787
07-6.787-5.091-6.7871.384
08-6.787-3.388-3.8771.372
091.232-2.584-0.852-2.646
10-0.308-1.5821.118-6.15
111.316-3.806-1.489-3.699
12-6.15-4.588-4.7491.381
13-4.367-1.882-4.8721.342
141.356-4.154-3.116-2.815
150.423-0.3150.182-0.609
16-0.4720.413-0.2040.048
Standard thresholds
P-value Threshold
0.001 -2.06819
0.0005 -0.23934
0.0001 3.58521