MotifMITF.H12INVIVO.0.P.B
Gene (human)MITF
(GeneCards)
Gene synonyms (human)BHLHE32
Gene (mouse)Mitf
Gene synonyms (mouse)Bw, Mi, Vit
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length11
ConsensusvbChYGTGACh
GC content57.23%
Information content (bits; total / per base)11.198 / 1.018
Data sourcesChIP-Seq
Aligned words1000

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 10 (58) 0.887 0.996 0.807 0.987 0.856 0.997 3.558 7.97 189.136 1120.62
Mouse 1 (5) 0.821 0.832 0.723 0.738 0.777 0.793 2.584 2.649 177.222 191.886

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 17.184 12.587 0.287 0.235
TF superclassBasic domains {1} (TFClass)
TF classBasic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF familybHLH-ZIP {1.2.6} (TFClass)
TF subfamilyTFE3 {1.2.6.1} (TFClass)
TFClass IDTFClass: 1.2.6.1.4
HGNCHGNC:7105
MGIMGI:104554
EntrezGene (human)GeneID:4286
(SSTAR profile)
EntrezGene (mouse)GeneID:17342
(SSTAR profile)
UniProt ID (human)MITF_HUMAN
UniProt ID (mouse)MITF_MOUSE
UniProt AC (human)O75030
(TFClass)
UniProt AC (mouse)Q08874
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 10 human, 1 mouse
HT-SELEX 0
Methyl-HT-SELEX 0
PCM
ACGT
01330.0187.0366.0117.0
0274.0261.0255.0410.0
0310.0983.04.03.0
04578.0104.088.0230.0
055.0674.065.0256.0
06139.072.0788.01.0
077.01.028.0964.0
080.03.0995.02.0
09953.018.015.014.0
105.0845.034.0116.0
11156.0402.0107.0335.0
PFM
ACGT
010.330.1870.3660.117
020.0740.2610.2550.41
030.010.9830.0040.003
040.5780.1040.0880.23
050.0050.6740.0650.256
060.1390.0720.7880.001
070.0070.0010.0280.964
080.00.0030.9950.002
090.9530.0180.0150.014
100.0050.8450.0340.116
110.1560.4020.1070.335
PWM
ACGT
010.276-0.2880.379-0.752
02-1.2010.0430.020.492
03-3.0661.364-3.783-3.975
040.834-0.867-1.032-0.083
05-3.6220.987-1.3280.024
06-0.582-1.2281.143-4.525
07-3.362-4.525-2.1361.345
08-4.982-3.9751.376-4.213
091.333-2.546-2.711-2.773
10-3.6221.213-1.952-0.76
11-0.4670.472-0.840.291
Standard thresholds
P-value Threshold
0.001 4.34378
0.0005 5.383285
0.0001 7.47678