MITF.H12CORE.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MITF.H12CORE.0.P.B
Gene (human)	MITF (GeneCards)
Gene synonyms (human)	BHLHE32
Gene (mouse)	Mitf
Gene synonyms (mouse)	Bw, Mi, Vit
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	11
Consensus	vbChYGTGACh
GC content	57.31%
Information content (bits; total / per base)	11.198 / 1.018
Data sources	ChIP-Seq
Aligned words	1000

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	10 (58)	0.886	0.996	0.806	0.987	0.855	0.997	3.538	7.95	189.29	1122.921
Mouse	1 (5)	0.821	0.831	0.722	0.737	0.778	0.793	2.582	2.649	171.824	189.143

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	23.314	13.744	0.297	0.242

TF superclass	Basic domains {1} (TFClass)
TF class	Basic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF family	bHLH-ZIP {1.2.6} (TFClass)
TF subfamily	TFE3 {1.2.6.1} (TFClass)
TFClass ID	TFClass: 1.2.6.1.4
HGNC	HGNC:7105
MGI	MGI:104554
EntrezGene (human)	GeneID:4286 (SSTAR profile)
EntrezGene (mouse)	GeneID:17342 (SSTAR profile)
UniProt ID (human)	MITF_HUMAN
UniProt ID (mouse)	MITF_MOUSE
UniProt AC (human)	O75030 (TFClass)
UniProt AC (mouse)	Q08874 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	10 human, 1 mouse
HT-SELEX	0
Methyl-HT-SELEX	0

PCM	MITF.H12CORE.0.P.B.pcm
PWM	MITF.H12CORE.0.P.B.pwm
PFM	MITF.H12CORE.0.P.B.pfm
Alignment	MITF.H12CORE.0.P.B.words.tsv
Threshold to P-value map	MITF.H12CORE.0.P.B.thr
Motif in other formats
JASPAR format	MITF.H12CORE.0.P.B_jaspar_format.txt
MEME format	MITF.H12CORE.0.P.B_meme_format.meme
Transfac format	MITF.H12CORE.0.P.B_transfac_format.txt
Homer format	MITF.H12CORE.0.P.B_homer_format_0.001.txt MITF.H12CORE.0.P.B_homer_format_0.0005.txt MITF.H12CORE.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	334.0	192.0	367.0	107.0
02	78.0	284.0	251.0	387.0
03	9.0	987.0	2.0	2.0
04	563.0	102.0	90.0	245.0
05	4.0	674.0	81.0	241.0
06	161.0	64.0	774.0	1.0
07	8.0	1.0	31.0	960.0
08	0.0	4.0	995.0	1.0
09	956.0	16.0	17.0	11.0
10	3.0	849.0	30.0	118.0
11	158.0	397.0	96.0	349.0

PFM

	A	C	G	T
01	0.334	0.192	0.367	0.107
02	0.078	0.284	0.251	0.387
03	0.009	0.987	0.002	0.002
04	0.563	0.102	0.09	0.245
05	0.004	0.674	0.081	0.241
06	0.161	0.064	0.774	0.001
07	0.008	0.001	0.031	0.96
08	0.0	0.004	0.995	0.001
09	0.956	0.016	0.017	0.011
10	0.003	0.849	0.03	0.118
11	0.158	0.397	0.096	0.349

PWM

	A	C	G	T
01	0.288	-0.262	0.382	-0.84
02	-1.15	0.127	0.004	0.435
03	-3.156	1.368	-4.213	-4.213
04	0.808	-0.887	-1.01	-0.02
05	-3.783	0.987	-1.113	-0.036
06	-0.436	-1.343	1.125	-4.525
07	-3.253	-4.525	-2.04	1.34
08	-4.982	-3.783	1.376	-4.525
09	1.336	-2.653	-2.598	-2.985
10	-3.975	1.218	-2.071	-0.743
11	-0.455	0.46	-0.946	0.332

Standard thresholds

P-value	Threshold
0.001	4.329745
0.0005	5.388245
0.0001	7.481975