MGAP.H12INVIVO.1.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MGAP.H12INVIVO.1.S.B
Gene (human)	MGA (GeneCards)
Gene synonyms (human)	KIAA0518, MAD5
Gene (mouse)	Mga
Gene synonyms (mouse)	Kiaa4252
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	18
Consensus	nRSGTGTGAWWWYYMvSR
GC content	45.84%
Information content (bits; total / per base)	18.418 / 1.023
Data sources	HT-SELEX
Aligned words	883

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (7)	0.55	0.558	0.361	0.371	0.54	0.587	1.174	1.292	0	0.06

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.867	0.873	0.72	0.738	0.613	0.642
Non-Methyl HT-SELEX, 2 experiments	best	0.997	0.997	0.827	0.845	0.668	0.708

TF superclass	Basic domains {1} (TFClass)
TF class	Basic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF family	bHLH-ZIP {1.2.6} (TFClass)
TF subfamily	MAD {1.2.6.7} (TFClass)
TFClass ID	TFClass: 1.2.6.7.4
HGNC	HGNC:14010
MGI	MGI:1352483
EntrezGene (human)	GeneID:23269 (SSTAR profile)
EntrezGene (mouse)	GeneID:29808 (SSTAR profile)
UniProt ID (human)	MGAP_HUMAN
UniProt ID (mouse)	MGAP_MOUSE
UniProt AC (human)	Q8IWI9 (TFClass)
UniProt AC (mouse)	A2AWL7 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 0 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	MGAP.H12INVIVO.1.S.B.pcm
PWM	MGAP.H12INVIVO.1.S.B.pwm
PFM	MGAP.H12INVIVO.1.S.B.pfm
Alignment	MGAP.H12INVIVO.1.S.B.words.tsv
Threshold to P-value map	MGAP.H12INVIVO.1.S.B.thr
Motif in other formats
JASPAR format	MGAP.H12INVIVO.1.S.B_jaspar_format.txt
MEME format	MGAP.H12INVIVO.1.S.B_meme_format.meme
Transfac format	MGAP.H12INVIVO.1.S.B_transfac_format.txt
Homer format	MGAP.H12INVIVO.1.S.B_homer_format_0.001.txt MGAP.H12INVIVO.1.S.B_homer_format_0.0005.txt MGAP.H12INVIVO.1.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	248.5	170.5	268.5	195.5
02	591.75	55.75	168.75	66.75
03	71.0	86.0	687.0	39.0
04	4.0	8.0	866.0	5.0
05	0.0	43.0	0.0	840.0
06	0.0	0.0	883.0	0.0
07	8.0	30.0	3.0	842.0
08	7.0	3.0	852.0	21.0
09	866.0	2.0	11.0	4.0
10	683.0	35.0	51.0	114.0
11	437.0	55.0	55.0	336.0
12	148.0	54.0	47.0	634.0
13	98.0	122.0	52.0	611.0
14	74.0	130.0	36.0	643.0
15	141.0	601.0	81.0	60.0
16	450.0	116.0	227.0	90.0
17	37.75	694.75	111.75	38.75
18	147.0	71.0	609.0	56.0

PFM

	A	C	G	T
01	0.281	0.193	0.304	0.221
02	0.67	0.063	0.191	0.076
03	0.08	0.097	0.778	0.044
04	0.005	0.009	0.981	0.006
05	0.0	0.049	0.0	0.951
06	0.0	0.0	1.0	0.0
07	0.009	0.034	0.003	0.954
08	0.008	0.003	0.965	0.024
09	0.981	0.002	0.012	0.005
10	0.773	0.04	0.058	0.129
11	0.495	0.062	0.062	0.381
12	0.168	0.061	0.053	0.718
13	0.111	0.138	0.059	0.692
14	0.084	0.147	0.041	0.728
15	0.16	0.681	0.092	0.068
16	0.51	0.131	0.257	0.102
17	0.043	0.787	0.127	0.044
18	0.166	0.08	0.69	0.063

PWM

	A	C	G	T
01	0.118	-0.256	0.194	-0.12
02	0.981	-1.354	-0.266	-1.179
03	-1.118	-0.931	1.13	-1.699
04	-3.665	-3.133	1.361	-3.503
05	-4.877	-1.605	-4.877	1.331
06	-4.877	-4.877	1.381	-4.877
07	-3.133	-1.948	-3.858	1.333
08	-3.242	-3.858	1.345	-2.283
09	1.361	-4.097	-2.863	-3.665
10	1.124	-1.802	-1.44	-0.654
11	0.679	-1.367	-1.367	0.417
12	-0.396	-1.385	-1.519	1.05
13	-0.803	-0.587	-1.421	1.013
14	-1.078	-0.524	-1.775	1.064
15	-0.444	0.997	-0.99	-1.282
16	0.708	-0.637	0.028	-0.886
17	-1.73	1.141	-0.673	-1.705
18	-0.403	-1.118	1.01	-1.349

Standard thresholds

P-value	Threshold
0.001	1.39696
0.0005	2.73621
0.0001	5.54766