MGAP.H12INVIVO.0.P.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MGAP.H12INVIVO.0.P.C
Gene (human)	MGA (GeneCards)
Gene synonyms (human)	KIAA0518, MAD5
Gene (mouse)	Mga
Gene synonyms (mouse)	Kiaa4252
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	C

Motif length	11
Consensus	vdSCACGWGSb
GC content	66.16%
Information content (bits; total / per base)	10.816 / 0.983
Data sources	ChIP-Seq
Aligned words	1000

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (7)	0.865	0.919	0.752	0.847	0.82	0.859	2.604	2.86	195.638	243.268

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.595	0.556	0.576	0.546	0.554	0.536
Non-Methyl HT-SELEX, 2 experiments	best	0.601	0.559	0.581	0.55	0.556	0.538

TF superclass	Basic domains {1} (TFClass)
TF class	Basic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF family	bHLH-ZIP {1.2.6} (TFClass)
TF subfamily	MAD {1.2.6.7} (TFClass)
TFClass ID	TFClass: 1.2.6.7.4
HGNC	HGNC:14010
MGI	MGI:1352483
EntrezGene (human)	GeneID:23269 (SSTAR profile)
EntrezGene (mouse)	GeneID:29808 (SSTAR profile)
UniProt ID (human)	MGAP_HUMAN
UniProt ID (mouse)	MGAP_MOUSE
UniProt AC (human)	Q8IWI9 (TFClass)
UniProt AC (mouse)	A2AWL7 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 0 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	MGAP.H12INVIVO.0.P.C.pcm
PWM	MGAP.H12INVIVO.0.P.C.pwm
PFM	MGAP.H12INVIVO.0.P.C.pfm
Alignment	MGAP.H12INVIVO.0.P.C.words.tsv
Threshold to P-value map	MGAP.H12INVIVO.0.P.C.thr
Motif in other formats
JASPAR format	MGAP.H12INVIVO.0.P.C_jaspar_format.txt
MEME format	MGAP.H12INVIVO.0.P.C_meme_format.meme
Transfac format	MGAP.H12INVIVO.0.P.C_transfac_format.txt
Homer format	MGAP.H12INVIVO.0.P.C_homer_format_0.001.txt MGAP.H12INVIVO.0.P.C_homer_format_0.0005.txt MGAP.H12INVIVO.0.P.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	234.0	266.0	432.0	68.0
02	473.0	72.0	302.0	153.0
03	132.0	147.0	642.0	79.0
04	12.0	983.0	5.0	0.0
05	974.0	2.0	19.0	5.0
06	5.0	823.0	44.0	128.0
07	122.0	7.0	867.0	4.0
08	139.0	134.0	4.0	723.0
09	8.0	3.0	975.0	14.0
10	83.0	97.0	756.0	64.0
11	109.0	446.0	252.0	193.0

PFM

	A	C	G	T
01	0.234	0.266	0.432	0.068
02	0.473	0.072	0.302	0.153
03	0.132	0.147	0.642	0.079
04	0.012	0.983	0.005	0.0
05	0.974	0.002	0.019	0.005
06	0.005	0.823	0.044	0.128
07	0.122	0.007	0.867	0.004
08	0.139	0.134	0.004	0.723
09	0.008	0.003	0.975	0.014
10	0.083	0.097	0.756	0.064
11	0.109	0.446	0.252	0.193

PWM

	A	C	G	T
01	-0.066	0.062	0.544	-1.284
02	0.634	-1.228	0.188	-0.487
03	-0.633	-0.526	0.939	-1.137
04	-2.909	1.364	-3.622	-4.982
05	1.355	-4.213	-2.497	-3.622
06	-3.622	1.187	-1.706	-0.663
07	-0.71	-3.362	1.239	-3.783
08	-0.582	-0.618	-3.783	1.057
09	-3.253	-3.975	1.356	-2.773
10	-1.089	-0.936	1.102	-1.343
11	-0.821	0.576	0.008	-0.257

Standard thresholds

P-value	Threshold
0.001	4.557515
0.0005	5.51162
0.0001	7.37383