MGAP.H12CORE.0.P.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MGAP.H12CORE.0.P.C
Gene (human)	MGA (GeneCards)
Gene synonyms (human)	KIAA0518, MAD5
Gene (mouse)	Mga
Gene synonyms (mouse)	Kiaa4252
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	C

Motif length	10
Consensus	dKCACGYGKb
GC content	67.41%
Information content (bits; total / per base)	10.49 / 1.049
Data sources	ChIP-Seq
Aligned words	999

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (7)	0.858	0.898	0.744	0.82	0.814	0.835	2.515	2.653	205.509	229.824

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.607	0.563	0.582	0.551	0.558	0.539
Non-Methyl HT-SELEX, 2 experiments	best	0.62	0.57	0.592	0.558	0.564	0.544

TF superclass	Basic domains {1} (TFClass)
TF class	Basic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF family	bHLH-ZIP {1.2.6} (TFClass)
TF subfamily	MAD {1.2.6.7} (TFClass)
TFClass ID	TFClass: 1.2.6.7.4
HGNC	HGNC:14010
MGI	MGI:1352483
EntrezGene (human)	GeneID:23269 (SSTAR profile)
EntrezGene (mouse)	GeneID:29808 (SSTAR profile)
UniProt ID (human)	MGAP_HUMAN
UniProt ID (mouse)	MGAP_MOUSE
UniProt AC (human)	Q8IWI9 (TFClass)
UniProt AC (mouse)	A2AWL7 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 0 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	MGAP.H12CORE.0.P.C.pcm
PWM	MGAP.H12CORE.0.P.C.pwm
PFM	MGAP.H12CORE.0.P.C.pfm
Alignment	MGAP.H12CORE.0.P.C.words.tsv
Threshold to P-value map	MGAP.H12CORE.0.P.C.thr
Motif in other formats
JASPAR format	MGAP.H12CORE.0.P.C_jaspar_format.txt
MEME format	MGAP.H12CORE.0.P.C_meme_format.meme
Transfac format	MGAP.H12CORE.0.P.C_transfac_format.txt
Homer format	MGAP.H12CORE.0.P.C_homer_format_0.001.txt MGAP.H12CORE.0.P.C_homer_format_0.0005.txt MGAP.H12CORE.0.P.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	453.0	97.0	340.0	109.0
02	92.0	112.0	678.0	117.0
03	8.0	983.0	8.0	0.0
04	961.0	3.0	31.0	4.0
05	5.0	813.0	109.0	72.0
06	103.0	8.0	874.0	14.0
07	152.0	158.0	7.0	682.0
08	6.0	2.0	975.0	16.0
09	69.0	71.0	768.0	91.0
10	103.0	439.0	258.0	199.0

PFM

	A	C	G	T
01	0.453	0.097	0.34	0.109
02	0.092	0.112	0.679	0.117
03	0.008	0.984	0.008	0.0
04	0.962	0.003	0.031	0.004
05	0.005	0.814	0.109	0.072
06	0.103	0.008	0.875	0.014
07	0.152	0.158	0.007	0.683
08	0.006	0.002	0.976	0.016
09	0.069	0.071	0.769	0.091
10	0.103	0.439	0.258	0.199

PWM

	A	C	G	T
01	0.592	-0.935	0.307	-0.82
02	-0.987	-0.794	0.994	-0.751
03	-3.252	1.365	-3.252	-4.981
04	1.342	-3.974	-2.039	-3.782
05	-3.621	1.176	-0.82	-1.227
06	-0.876	-3.252	1.248	-2.772
07	-0.492	-0.454	-3.361	1.0
08	-3.483	-4.212	1.357	-2.652
09	-1.269	-1.241	1.119	-0.998
10	-0.876	0.561	0.032	-0.225

Standard thresholds

P-value	Threshold
0.001	4.644985
0.0005	5.570495
0.0001	7.32033