MEOX1.H12RSNP.0.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MEOX1.H12RSNP.0.SM.B
Gene (human)	MEOX1 (GeneCards)
Gene synonyms (human)	MOX1
Gene (mouse)	Meox1
Gene synonyms (mouse)	Mox-1, Mox1
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	13
Consensus	nnvbTAATKAbnn
GC content	33.27%
Information content (bits; total / per base)	10.518 / 0.809
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	2480

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.882	0.848	0.805	0.78	0.742	0.725
Overall, 4 experiments	best	0.975	0.959	0.958	0.936	0.919	0.892
Methyl HT-SELEX, 1 experiments	median	0.975	0.959	0.958	0.936	0.919	0.892
Methyl HT-SELEX, 1 experiments	best	0.975	0.959	0.958	0.936	0.919	0.892
Non-Methyl HT-SELEX, 3 experiments	median	0.821	0.786	0.687	0.677	0.6	0.609
Non-Methyl HT-SELEX, 3 experiments	best	0.943	0.91	0.923	0.882	0.884	0.841

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.628	0.184	0.582	0.351

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	HOX-related {3.1.1} (TFClass)
TF subfamily	MEOX {3.1.1.14} (TFClass)
TFClass ID	TFClass: 3.1.1.14.1
HGNC	HGNC:7013
MGI	MGI:103220
EntrezGene (human)	GeneID:4222 (SSTAR profile)
EntrezGene (mouse)	GeneID:17285 (SSTAR profile)
UniProt ID (human)	MEOX1_HUMAN
UniProt ID (mouse)	MEOX1_MOUSE
UniProt AC (human)	P50221 (TFClass)
UniProt AC (mouse)	P32442 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	3
Methyl-HT-SELEX	1

PCM	MEOX1.H12RSNP.0.SM.B.pcm
PWM	MEOX1.H12RSNP.0.SM.B.pwm
PFM	MEOX1.H12RSNP.0.SM.B.pfm
Alignment	MEOX1.H12RSNP.0.SM.B.words.tsv
Threshold to P-value map	MEOX1.H12RSNP.0.SM.B.thr
Motif in other formats
JASPAR format	MEOX1.H12RSNP.0.SM.B_jaspar_format.txt
MEME format	MEOX1.H12RSNP.0.SM.B_meme_format.meme
Transfac format	MEOX1.H12RSNP.0.SM.B_transfac_format.txt
Homer format	MEOX1.H12RSNP.0.SM.B_homer_format_0.001.txt MEOX1.H12RSNP.0.SM.B_homer_format_0.0005.txt MEOX1.H12RSNP.0.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	694.5	568.5	679.5	537.5
02	617.75	780.75	619.75	461.75
03	714.0	608.0	905.0	253.0
04	78.0	852.0	560.0	990.0
05	1.0	5.0	4.0	2470.0
06	2474.0	6.0	0.0	0.0
07	2479.0	0.0	1.0	0.0
08	0.0	3.0	2.0	2475.0
09	10.0	108.0	630.0	1732.0
10	2034.0	84.0	310.0	52.0
11	279.0	943.0	539.0	719.0
12	477.0	758.0	637.0	608.0
13	635.5	598.5	523.5	722.5

PFM

	A	C	G	T
01	0.28	0.229	0.274	0.217
02	0.249	0.315	0.25	0.186
03	0.288	0.245	0.365	0.102
04	0.031	0.344	0.226	0.399
05	0.0	0.002	0.002	0.996
06	0.998	0.002	0.0	0.0
07	1.0	0.0	0.0	0.0
08	0.0	0.001	0.001	0.998
09	0.004	0.044	0.254	0.698
10	0.82	0.034	0.125	0.021
11	0.113	0.38	0.217	0.29
12	0.192	0.306	0.257	0.245
13	0.256	0.241	0.211	0.291

PWM

	A	C	G	T
01	0.113	-0.086	0.091	-0.142
02	-0.004	0.23	-0.0	-0.294
03	0.141	-0.019	0.377	-0.892
04	-2.051	0.317	-0.101	0.467
05	-5.35	-4.494	-4.649	1.38
06	1.382	-4.359	-5.763	-5.763
07	1.384	-5.763	-5.35	-5.763
08	-5.763	-4.833	-5.058	1.382
09	-3.952	-1.733	0.016	1.025
10	1.186	-1.979	-0.69	-2.445
11	-0.795	0.418	-0.14	0.148
12	-0.261	0.2	0.027	-0.019
13	0.025	-0.035	-0.169	0.153

Standard thresholds

P-value	Threshold
0.001	4.66621
0.0005	5.84531
0.0001	7.817315