MEOX1.H12CORE.0.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MEOX1.H12CORE.0.SM.B
Gene (human)	MEOX1 (GeneCards)
Gene synonyms (human)	MOX1
Gene (mouse)	Meox1
Gene synonyms (mouse)	Mox-1, Mox1
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	13
Consensus	nvvbTAATKAbbn
GC content	38.08%
Information content (bits; total / per base)	11.113 / 0.855
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	9750

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.89	0.858	0.811	0.788	0.748	0.733
Overall, 4 experiments	best	0.979	0.967	0.963	0.944	0.929	0.904
Methyl HT-SELEX, 1 experiments	median	0.979	0.967	0.963	0.944	0.929	0.904
Methyl HT-SELEX, 1 experiments	best	0.979	0.967	0.963	0.944	0.929	0.904
Non-Methyl HT-SELEX, 3 experiments	median	0.826	0.788	0.692	0.68	0.601	0.61
Non-Methyl HT-SELEX, 3 experiments	best	0.955	0.928	0.931	0.897	0.896	0.857

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.611	0.188	0.552	0.301

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	HOX-related {3.1.1} (TFClass)
TF subfamily	MEOX {3.1.1.14} (TFClass)
TFClass ID	TFClass: 3.1.1.14.1
HGNC	HGNC:7013
MGI	MGI:103220
EntrezGene (human)	GeneID:4222 (SSTAR profile)
EntrezGene (mouse)	GeneID:17285 (SSTAR profile)
UniProt ID (human)	MEOX1_HUMAN
UniProt ID (mouse)	MEOX1_MOUSE
UniProt AC (human)	P50221 (TFClass)
UniProt AC (mouse)	P32442 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	3
Methyl-HT-SELEX	1

PCM	MEOX1.H12CORE.0.SM.B.pcm
PWM	MEOX1.H12CORE.0.SM.B.pwm
PFM	MEOX1.H12CORE.0.SM.B.pfm
Alignment	MEOX1.H12CORE.0.SM.B.words.tsv
Threshold to P-value map	MEOX1.H12CORE.0.SM.B.thr
Motif in other formats
JASPAR format	MEOX1.H12CORE.0.SM.B_jaspar_format.txt
MEME format	MEOX1.H12CORE.0.SM.B_meme_format.meme
Transfac format	MEOX1.H12CORE.0.SM.B_transfac_format.txt
Homer format	MEOX1.H12CORE.0.SM.B_homer_format_0.001.txt MEOX1.H12CORE.0.SM.B_homer_format_0.0005.txt MEOX1.H12CORE.0.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2632.0	2390.0	2595.0	2133.0
02	2015.25	4404.25	1893.25	1437.25
03	2256.0	2667.0	4422.0	405.0
04	447.0	4327.0	1680.0	3296.0
05	0.0	3.0	0.0	9747.0
06	9686.0	0.0	64.0	0.0
07	9750.0	0.0	0.0	0.0
08	0.0	179.0	0.0	9571.0
09	0.0	361.0	2905.0	6484.0
10	8184.0	55.0	1430.0	81.0
11	791.0	4675.0	2516.0	1768.0
12	1225.0	3336.0	3321.0	1868.0
13	2249.0	2734.0	2305.0	2462.0

PFM

	A	C	G	T
01	0.27	0.245	0.266	0.219
02	0.207	0.452	0.194	0.147
03	0.231	0.274	0.454	0.042
04	0.046	0.444	0.172	0.338
05	0.0	0.0	0.0	1.0
06	0.993	0.0	0.007	0.0
07	1.0	0.0	0.0	0.0
08	0.0	0.018	0.0	0.982
09	0.0	0.037	0.298	0.665
10	0.839	0.006	0.147	0.008
11	0.081	0.479	0.258	0.181
12	0.126	0.342	0.341	0.192
13	0.231	0.28	0.236	0.253

PWM

	A	C	G	T
01	0.077	-0.02	0.063	-0.133
02	-0.19	0.591	-0.252	-0.528
03	-0.077	0.09	0.595	-1.79
04	-1.692	0.573	-0.372	0.301
05	-6.968	-6.133	-6.968	1.385
06	1.379	-6.968	-3.606	-6.968
07	1.386	-6.968	-6.968	-6.968
08	-6.968	-2.6	-6.968	1.367
09	-6.968	-1.904	0.175	0.978
10	1.211	-3.751	-0.533	-3.377
11	-1.123	0.651	0.032	-0.321
12	-0.687	0.314	0.309	-0.266
13	-0.08	0.115	-0.056	0.01

Standard thresholds

P-value	Threshold
0.001	4.14671
0.0005	5.63142
0.0001	7.77722