| Motif | MEIS3.H12RSNP.0.SM.B |
| Gene (human) | MEIS3 (GeneCards) |
| Gene synonyms (human) | MRG2 |
| Gene (mouse) | Meis3 |
| Gene synonyms (mouse) | Mrg2 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | B |
| Motif | MEIS3.H12RSNP.0.SM.B |
| Gene (human) | MEIS3 (GeneCards) |
| Gene synonyms (human) | MRG2 |
| Gene (mouse) | Meis3 |
| Gene synonyms (mouse) | Mrg2 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | B |
| Motif length | 9 |
| Consensus | hTGACAGvb |
| GC content | 49.97% |
| Information content (bits; total / per base) | 11.782 / 1.309 |
| Data sources | HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 2178 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 6 experiments | median | 0.989 | 0.983 | 0.975 | 0.964 | 0.899 | 0.894 |
| best | 0.995 | 0.992 | 0.989 | 0.983 | 0.983 | 0.974 | |
| Methyl HT-SELEX, 1 experiments | median | 0.99 | 0.984 | 0.983 | 0.972 | 0.975 | 0.96 |
| best | 0.99 | 0.984 | 0.983 | 0.972 | 0.975 | 0.96 | |
| Non-Methyl HT-SELEX, 5 experiments | median | 0.988 | 0.982 | 0.968 | 0.956 | 0.879 | 0.871 |
| best | 0.995 | 0.992 | 0.989 | 0.983 | 0.983 | 0.974 | |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 1 | 0.973 | 0.894 | 0.948 | 0.605 |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Homeo domain factors {3.1} (TFClass) |
| TF family | TALE-type HD {3.1.4} (TFClass) |
| TF subfamily | MEIS {3.1.4.2} (TFClass) |
| TFClass ID | TFClass: 3.1.4.2.3 |
| HGNC | HGNC:29537 |
| MGI | MGI:108519 |
| EntrezGene (human) | GeneID:56917 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:17537 (SSTAR profile) |
| UniProt ID (human) | MEIS3_HUMAN |
| UniProt ID (mouse) | MEIS3_MOUSE |
| UniProt AC (human) | Q99687 (TFClass) |
| UniProt AC (mouse) | P97368 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 0 mouse |
| HT-SELEX | 5 |
| Methyl-HT-SELEX | 1 |
| PCM | MEIS3.H12RSNP.0.SM.B.pcm |
| PWM | MEIS3.H12RSNP.0.SM.B.pwm |
| PFM | MEIS3.H12RSNP.0.SM.B.pfm |
| Alignment | MEIS3.H12RSNP.0.SM.B.words.tsv |
| Threshold to P-value map | MEIS3.H12RSNP.0.SM.B.thr |
| Motif in other formats | |
| JASPAR format | MEIS3.H12RSNP.0.SM.B_jaspar_format.txt |
| MEME format | MEIS3.H12RSNP.0.SM.B_meme_format.meme |
| Transfac format | MEIS3.H12RSNP.0.SM.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 452.75 | 393.75 | 374.75 | 956.75 |
| 02 | 20.0 | 12.0 | 17.0 | 2129.0 |
| 03 | 0.0 | 0.0 | 2178.0 | 0.0 |
| 04 | 2178.0 | 0.0 | 0.0 | 0.0 |
| 05 | 0.0 | 2178.0 | 0.0 | 0.0 |
| 06 | 2178.0 | 0.0 | 0.0 | 0.0 |
| 07 | 65.0 | 49.0 | 1964.0 | 100.0 |
| 08 | 207.5 | 870.5 | 902.5 | 197.5 |
| 09 | 324.25 | 444.25 | 411.25 | 998.25 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.208 | 0.181 | 0.172 | 0.439 |
| 02 | 0.009 | 0.006 | 0.008 | 0.978 |
| 03 | 0.0 | 0.0 | 1.0 | 0.0 |
| 04 | 1.0 | 0.0 | 0.0 | 0.0 |
| 05 | 0.0 | 1.0 | 0.0 | 0.0 |
| 06 | 1.0 | 0.0 | 0.0 | 0.0 |
| 07 | 0.03 | 0.022 | 0.902 | 0.046 |
| 08 | 0.095 | 0.4 | 0.414 | 0.091 |
| 09 | 0.149 | 0.204 | 0.189 | 0.458 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.184 | -0.323 | -0.372 | 0.562 |
| 02 | -3.216 | -3.67 | -3.363 | 1.361 |
| 03 | -5.65 | -5.65 | 1.384 | -5.65 |
| 04 | 1.384 | -5.65 | -5.65 | -5.65 |
| 05 | -5.65 | 1.384 | -5.65 | -5.65 |
| 06 | 1.384 | -5.65 | -5.65 | -5.65 |
| 07 | -2.1 | -2.373 | 1.28 | -1.679 |
| 08 | -0.959 | 0.468 | 0.504 | -1.008 |
| 09 | -0.516 | -0.203 | -0.28 | 0.605 |
| P-value | Threshold |
|---|---|
| 0.001 | 3.569405 |
| 0.0005 | 4.857785 |
| 0.0001 | 8.01311 |