MotifMEIS3.H12INVIVO.1.S.D
Gene (human)MEIS3
(GeneCards)
Gene synonyms (human)MRG2
Gene (mouse)Meis3
Gene synonyms (mouse)Mrg2
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
D
Motif length20
ConsensusnhTGACAGSTKKhMvvnnnn
GC content49.32%
Information content (bits; total / per base)15.337 / 0.767
Data sourcesHT-SELEX
Aligned words2236

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 6 experiments median 0.986 0.979 0.956 0.944 0.865 0.856
best 0.994 0.992 0.988 0.981 0.978 0.967
Methyl HT-SELEX, 1 experiments median 0.99 0.984 0.981 0.97 0.967 0.952
best 0.99 0.984 0.981 0.97 0.967 0.952
Non-Methyl HT-SELEX, 5 experiments median 0.982 0.975 0.94 0.923 0.842 0.83
best 0.994 0.992 0.988 0.981 0.978 0.967

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.832 0.644 0.789 0.505
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyTALE-type HD {3.1.4} (TFClass)
TF subfamilyMEIS {3.1.4.2} (TFClass)
TFClass IDTFClass: 3.1.4.2.3
HGNCHGNC:29537
MGIMGI:108519
EntrezGene (human)GeneID:56917
(SSTAR profile)
EntrezGene (mouse)GeneID:17537
(SSTAR profile)
UniProt ID (human)MEIS3_HUMAN
UniProt ID (mouse)MEIS3_MOUSE
UniProt AC (human)Q99687
(TFClass)
UniProt AC (mouse)P97368
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 5
Methyl-HT-SELEX 1
PCM
ACGT
01708.5603.5495.5428.5
02720.75670.75234.75609.75
0376.0130.027.02003.0
042.00.02234.00.0
052092.01.010.0133.0
060.02234.00.02.0
072233.00.03.00.0
0850.0167.01992.027.0
0936.01603.0552.045.0
1032.0230.041.01933.0
11103.091.01421.0621.0
12129.0116.0516.01475.0
13262.01327.0242.0405.0
141380.0478.0157.0221.0
151125.0436.0368.0307.0
16875.0469.0555.0337.0
17527.0693.0597.0419.0
18449.0489.0540.0758.0
19416.75512.75619.75686.75
20422.25536.25662.25615.25
PFM
ACGT
010.3170.270.2220.192
020.3220.30.1050.273
030.0340.0580.0120.896
040.0010.00.9990.0
050.9360.00.0040.059
060.00.9990.00.001
070.9990.00.0010.0
080.0220.0750.8910.012
090.0160.7170.2470.02
100.0140.1030.0180.864
110.0460.0410.6360.278
120.0580.0520.2310.66
130.1170.5930.1080.181
140.6170.2140.070.099
150.5030.1950.1650.137
160.3910.210.2480.151
170.2360.310.2670.187
180.2010.2190.2420.339
190.1860.2290.2770.307
200.1890.240.2960.275
PWM
ACGT
010.2360.076-0.12-0.265
020.2530.182-0.8630.087
03-1.974-1.447-2.9651.274
04-4.961-5.6731.383-5.673
051.317-5.255-3.851-1.425
06-5.6731.383-5.673-4.961
071.382-5.673-4.735-5.673
08-2.38-1.21.268-2.965
09-2.6941.051-0.013-2.481
10-2.805-0.883-2.571.238
11-1.676-1.7980.9310.105
12-1.455-1.56-0.080.968
13-0.7540.863-0.833-0.321
140.902-0.156-1.261-0.923
150.698-0.248-0.416-0.596
160.447-0.175-0.007-0.504
17-0.0590.2140.066-0.287
18-0.218-0.133-0.0340.304
19-0.292-0.0860.1030.205
20-0.279-0.0410.1690.096
Standard thresholds
P-value Threshold
0.001 2.33116
0.0005 3.69626
0.0001 6.45171