MotifMEIS3.H12CORE.0.SM.B
Gene (human)MEIS3
(GeneCards)
Gene synonyms (human)MRG2
Gene (mouse)Meis3
Gene synonyms (mouse)Mrg2
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length8
ConsensusnTGACAbn
GC content45.97%
Information content (bits; total / per base)10.159 / 1.27
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words8090

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 6 experiments median 0.992 0.989 0.977 0.969 0.9 0.895
best 0.999 0.999 0.998 0.998 0.993 0.991
Methyl HT-SELEX, 1 experiments median 0.998 0.997 0.991 0.988 0.982 0.975
best 0.998 0.997 0.991 0.988 0.982 0.975
Non-Methyl HT-SELEX, 5 experiments median 0.988 0.983 0.967 0.955 0.879 0.872
best 0.999 0.999 0.998 0.998 0.993 0.991

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.968 0.881 0.954 0.582
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyTALE-type HD {3.1.4} (TFClass)
TF subfamilyMEIS {3.1.4.2} (TFClass)
TFClass IDTFClass: 3.1.4.2.3
HGNCHGNC:29537
MGIMGI:108519
EntrezGene (human)GeneID:56917
(SSTAR profile)
EntrezGene (mouse)GeneID:17537
(SSTAR profile)
UniProt ID (human)MEIS3_HUMAN
UniProt ID (mouse)MEIS3_MOUSE
UniProt AC (human)Q99687
(TFClass)
UniProt AC (mouse)P97368
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 5
Methyl-HT-SELEX 1
PCM
ACGT
012096.01979.01648.02367.0
020.00.00.08090.0
030.00.08090.00.0
048090.00.00.00.0
050.08090.00.00.0
068090.00.00.00.0
071449.01540.03428.01673.0
081618.752293.752682.751494.75
PFM
ACGT
010.2590.2450.2040.293
020.00.00.01.0
030.00.01.00.0
041.00.00.00.0
050.01.00.00.0
061.00.00.00.0
070.1790.190.4240.207
080.20.2840.3320.185
PWM
ACGT
010.036-0.022-0.2050.157
02-6.802-6.802-6.8021.385
03-6.802-6.8021.385-6.802
041.385-6.802-6.802-6.802
05-6.8021.385-6.802-6.802
061.385-6.802-6.802-6.802
07-0.333-0.2720.527-0.189
08-0.2220.1260.282-0.302
Standard thresholds
P-value Threshold
0.001 -0.029285
0.0005 6.760695
0.0001 7.469465