MotifMEIS2.H12INVITRO.2.SM.B
Gene (human)MEIS2
(GeneCards)
Gene synonyms (human)MRG1
Gene (mouse)Meis2
Gene synonyms (mouse)Mrg1, Stra10
LOGO
LOGO (reverse complement)
Motif subtype2
Quality
B
Motif length14
ConsensusnWTGACAGSTKdhv
GC content48.39%
Information content (bits; total / per base)16.129 / 1.152
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words616

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (7) 0.679 0.69 0.542 0.561 0.611 0.639 1.489 1.632 72.796 105.387

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 8 experiments median 0.964 0.948 0.905 0.882 0.794 0.783
best 0.997 0.996 0.993 0.989 0.985 0.978
Methyl HT-SELEX, 2 experiments median 0.964 0.948 0.905 0.882 0.794 0.783
best 0.973 0.96 0.921 0.902 0.795 0.792
Non-Methyl HT-SELEX, 6 experiments median 0.911 0.886 0.842 0.817 0.741 0.732
best 0.997 0.996 0.993 0.989 0.985 0.978

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 5.732 3.646 0.181 0.183

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.685 0.333 0.405 0.177
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyTALE-type HD {3.1.4} (TFClass)
TF subfamilyMEIS {3.1.4.2} (TFClass)
TFClass IDTFClass: 3.1.4.2.2
HGNCHGNC:7001
MGIMGI:108564
EntrezGene (human)GeneID:4212
(SSTAR profile)
EntrezGene (mouse)GeneID:17536
(SSTAR profile)
UniProt ID (human)MEIS2_HUMAN
UniProt ID (mouse)MEIS2_MOUSE
UniProt AC (human)O14770
(TFClass)
UniProt AC (mouse)P97367
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 0 mouse
HT-SELEX 6
Methyl-HT-SELEX 2
PCM
ACGT
01148.25148.25132.25187.25
02112.552.550.5400.5
030.00.00.0616.0
040.00.0616.00.0
05616.00.00.00.0
060.0616.00.00.0
07616.00.00.00.0
080.00.0613.03.0
097.0395.0212.02.0
106.073.014.0523.0
1145.032.0372.0167.0
12132.045.0152.0287.0
1378.5353.551.5132.5
14295.25167.2577.2576.25
PFM
ACGT
010.2410.2410.2150.304
020.1830.0850.0820.65
030.00.00.01.0
040.00.01.00.0
051.00.00.00.0
060.01.00.00.0
071.00.00.00.0
080.00.00.9950.005
090.0110.6410.3440.003
100.010.1190.0230.849
110.0730.0520.6040.271
120.2140.0730.2470.466
130.1270.5740.0840.215
140.4790.2720.1250.124
PWM
ACGT
01-0.038-0.038-0.1510.194
02-0.31-1.056-1.0940.949
03-4.574-4.574-4.5741.379
04-4.574-4.5741.379-4.574
051.379-4.574-4.574-4.574
06-4.5741.379-4.574-4.574
071.379-4.574-4.574-4.574
08-4.574-4.5741.374-3.52
09-2.8950.9360.317-3.765
10-3.018-0.735-2.31.215
11-1.206-1.5330.8760.08
12-0.152-1.206-0.0130.618
13-0.6640.825-1.075-0.149
140.6460.082-0.68-0.692
Standard thresholds
P-value Threshold
0.001 1.37952
0.0005 2.91001
0.0001 5.85332