MotifMEIS2.H12INVITRO.0.P.C
Gene (human)MEIS2
(GeneCards)
Gene synonyms (human)MRG1
Gene (mouse)Meis2
Gene synonyms (mouse)Mrg1, Stra10
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
C
Motif length10
ConsensusTGAbWdRYdd
GC content35.33%
Information content (bits; total / per base)7.959 / 0.796
Data sourcesChIP-Seq
Aligned words873

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (7) 0.777 0.826 0.684 0.718 0.751 0.809 2.429 2.828 258.959 313.523

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 8 experiments median 0.745 0.662 0.716 0.647 0.66 0.616
best 0.895 0.825 0.89 0.821 0.873 0.807
Methyl HT-SELEX, 2 experiments median 0.745 0.662 0.716 0.647 0.66 0.616
best 0.747 0.663 0.722 0.651 0.664 0.62
Non-Methyl HT-SELEX, 6 experiments median 0.713 0.648 0.685 0.63 0.64 0.604
best 0.895 0.825 0.89 0.821 0.873 0.807

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 5.398 3.533 0.137 0.165

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.521 0.081 0.209 0.05
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyTALE-type HD {3.1.4} (TFClass)
TF subfamilyMEIS {3.1.4.2} (TFClass)
TFClass IDTFClass: 3.1.4.2.2
HGNCHGNC:7001
MGIMGI:108564
EntrezGene (human)GeneID:4212
(SSTAR profile)
EntrezGene (mouse)GeneID:17536
(SSTAR profile)
UniProt ID (human)MEIS2_HUMAN
UniProt ID (mouse)MEIS2_MOUSE
UniProt AC (human)O14770
(TFClass)
UniProt AC (mouse)P97367
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 0 mouse
HT-SELEX 6
Methyl-HT-SELEX 2
PCM
ACGT
0175.01.015.0782.0
0218.02.0844.09.0
03805.028.026.014.0
0438.0257.0118.0460.0
05298.016.080.0479.0
06156.072.0354.0291.0
07691.069.085.028.0
0879.0152.051.0591.0
09187.037.0425.0224.0
10255.077.0375.0166.0
PFM
ACGT
010.0860.0010.0170.896
020.0210.0020.9670.01
030.9220.0320.030.016
040.0440.2940.1350.527
050.3410.0180.0920.549
060.1790.0820.4050.333
070.7920.0790.0970.032
080.090.1740.0580.677
090.2140.0420.4870.257
100.2920.0880.430.19
PWM
ACGT
01-1.054-4.403-2.5781.271
02-2.413-4.0871.347-3.024
031.3-2.002-2.072-2.64
04-1.7120.162-0.6080.742
050.309-2.52-0.990.782
06-0.333-1.0930.4810.286
071.147-1.135-0.931-2.002
08-1.003-0.358-1.4290.991
09-0.153-1.7380.6630.026
100.155-1.0280.538-0.271
Standard thresholds
P-value Threshold
0.001 5.08359
0.0005 5.78063
0.0001 7.10673