MotifMEIS2.H12CORE.1.PSM.A
Gene (human)MEIS2
(GeneCards)
Gene synonyms (human)MRG1
Gene (mouse)Meis2
Gene synonyms (mouse)Mrg1, Stra10
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
A
Motif length12
ConsensusndTGACAKvbbn
GC content51.3%
Information content (bits; total / per base)10.625 / 0.885
Data sourcesChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words9680

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (7) 0.736 0.745 0.575 0.59 0.662 0.675 1.624 1.716 114.854 158.26

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 8 experiments median 0.97 0.954 0.933 0.909 0.843 0.824
best 0.997 0.995 0.994 0.991 0.989 0.984
Methyl HT-SELEX, 2 experiments median 0.97 0.954 0.933 0.909 0.843 0.824
best 0.977 0.965 0.944 0.924 0.851 0.827
Non-Methyl HT-SELEX, 6 experiments median 0.931 0.904 0.871 0.846 0.775 0.764
best 0.997 0.995 0.994 0.991 0.989 0.984

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 3.465 2.223 0.173 0.164

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.707 0.367 0.485 0.237
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyTALE-type HD {3.1.4} (TFClass)
TF subfamilyMEIS {3.1.4.2} (TFClass)
TFClass IDTFClass: 3.1.4.2.2
HGNCHGNC:7001
MGIMGI:108564
EntrezGene (human)GeneID:4212
(SSTAR profile)
EntrezGene (mouse)GeneID:17536
(SSTAR profile)
UniProt ID (human)MEIS2_HUMAN
UniProt ID (mouse)MEIS2_MOUSE
UniProt AC (human)O14770
(TFClass)
UniProt AC (mouse)P97367
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 0 mouse
HT-SELEX 6
Methyl-HT-SELEX 2
PCM
ACGT
012481.752360.752531.752305.75
022526.251442.251752.253959.25
0328.01149.024.08479.0
040.00.09680.00.0
059675.00.05.00.0
060.09680.00.00.0
078987.00.0693.00.0
08910.0991.06726.01053.0
09786.03866.04245.0783.0
101066.02236.01178.05200.0
111358.51841.54133.52346.5
121792.251919.253133.252835.25
PFM
ACGT
010.2560.2440.2620.238
020.2610.1490.1810.409
030.0030.1190.0020.876
040.00.01.00.0
050.9990.00.0010.0
060.01.00.00.0
070.9280.00.0720.0
080.0940.1020.6950.109
090.0810.3990.4390.081
100.110.2310.1220.537
110.140.190.4270.242
120.1850.1980.3240.293
PWM
ACGT
010.025-0.0250.045-0.048
020.043-0.517-0.3230.492
03-4.382-0.744-4.5231.253
04-6.962-6.9621.386-6.962
051.385-6.962-5.805-6.962
06-6.9621.386-6.962-6.962
071.311-6.962-1.248-6.962
08-0.977-0.8911.022-0.831
09-1.1230.4680.562-1.126
10-0.819-0.079-0.7190.764
11-0.577-0.2730.535-0.031
12-0.3-0.2320.2580.158
Standard thresholds
P-value Threshold
0.001 4.809515
0.0005 5.86275
0.0001 7.584505