Motif | MEIS2.H12CORE.1.PSM.A |
Gene (human) | MEIS2 (GeneCards) |
Gene synonyms (human) | MRG1 |
Gene (mouse) | Meis2 |
Gene synonyms (mouse) | Mrg1, Stra10 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 1 |
Quality | A |
Motif | MEIS2.H12CORE.1.PSM.A |
Gene (human) | MEIS2 (GeneCards) |
Gene synonyms (human) | MRG1 |
Gene (mouse) | Meis2 |
Gene synonyms (mouse) | Mrg1, Stra10 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 1 |
Quality | A |
Motif length | 12 |
Consensus | ndTGACAKvbbn |
GC content | 51.3% |
Information content (bits; total / per base) | 10.625 / 0.885 |
Data sources | ChIP-Seq + HT-SELEX + Methyl-HT-SELEX |
Aligned words | 9680 |
ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
---|---|---|---|---|---|---|---|---|---|---|---|
Human | 1 (7) | 0.736 | 0.745 | 0.575 | 0.59 | 0.662 | 0.675 | 1.624 | 1.716 | 114.854 | 158.26 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 8 experiments | median | 0.97 | 0.954 | 0.933 | 0.909 | 0.843 | 0.824 |
best | 0.997 | 0.995 | 0.994 | 0.991 | 0.989 | 0.984 | |
Methyl HT-SELEX, 2 experiments | median | 0.97 | 0.954 | 0.933 | 0.909 | 0.843 | 0.824 |
best | 0.977 | 0.965 | 0.944 | 0.924 | 0.851 | 0.827 | |
Non-Methyl HT-SELEX, 6 experiments | median | 0.931 | 0.904 | 0.871 | 0.846 | 0.775 | 0.764 |
best | 0.997 | 0.995 | 0.994 | 0.991 | 0.989 | 0.984 |
rSNP benchmarking, ADASTRA | odds-ratio | -log-Fisher's P | Pearson r | Kendall tau |
---|---|---|---|---|
# | 3.465 | 2.223 | 0.173 | 0.164 |
rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
---|---|---|---|---|
batch 1 | 0.707 | 0.367 | 0.485 | 0.237 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Homeo domain factors {3.1} (TFClass) |
TF family | TALE-type HD {3.1.4} (TFClass) |
TF subfamily | MEIS {3.1.4.2} (TFClass) |
TFClass ID | TFClass: 3.1.4.2.2 |
HGNC | HGNC:7001 |
MGI | MGI:108564 |
EntrezGene (human) | GeneID:4212 (SSTAR profile) |
EntrezGene (mouse) | GeneID:17536 (SSTAR profile) |
UniProt ID (human) | MEIS2_HUMAN |
UniProt ID (mouse) | MEIS2_MOUSE |
UniProt AC (human) | O14770 (TFClass) |
UniProt AC (mouse) | P97367 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 1 human, 0 mouse |
HT-SELEX | 6 |
Methyl-HT-SELEX | 2 |
PCM | MEIS2.H12CORE.1.PSM.A.pcm |
PWM | MEIS2.H12CORE.1.PSM.A.pwm |
PFM | MEIS2.H12CORE.1.PSM.A.pfm |
Alignment | MEIS2.H12CORE.1.PSM.A.words.tsv |
Threshold to P-value map | MEIS2.H12CORE.1.PSM.A.thr |
Motif in other formats | |
JASPAR format | MEIS2.H12CORE.1.PSM.A_jaspar_format.txt |
MEME format | MEIS2.H12CORE.1.PSM.A_meme_format.meme |
Transfac format | MEIS2.H12CORE.1.PSM.A_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 2481.75 | 2360.75 | 2531.75 | 2305.75 |
02 | 2526.25 | 1442.25 | 1752.25 | 3959.25 |
03 | 28.0 | 1149.0 | 24.0 | 8479.0 |
04 | 0.0 | 0.0 | 9680.0 | 0.0 |
05 | 9675.0 | 0.0 | 5.0 | 0.0 |
06 | 0.0 | 9680.0 | 0.0 | 0.0 |
07 | 8987.0 | 0.0 | 693.0 | 0.0 |
08 | 910.0 | 991.0 | 6726.0 | 1053.0 |
09 | 786.0 | 3866.0 | 4245.0 | 783.0 |
10 | 1066.0 | 2236.0 | 1178.0 | 5200.0 |
11 | 1358.5 | 1841.5 | 4133.5 | 2346.5 |
12 | 1792.25 | 1919.25 | 3133.25 | 2835.25 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.256 | 0.244 | 0.262 | 0.238 |
02 | 0.261 | 0.149 | 0.181 | 0.409 |
03 | 0.003 | 0.119 | 0.002 | 0.876 |
04 | 0.0 | 0.0 | 1.0 | 0.0 |
05 | 0.999 | 0.0 | 0.001 | 0.0 |
06 | 0.0 | 1.0 | 0.0 | 0.0 |
07 | 0.928 | 0.0 | 0.072 | 0.0 |
08 | 0.094 | 0.102 | 0.695 | 0.109 |
09 | 0.081 | 0.399 | 0.439 | 0.081 |
10 | 0.11 | 0.231 | 0.122 | 0.537 |
11 | 0.14 | 0.19 | 0.427 | 0.242 |
12 | 0.185 | 0.198 | 0.324 | 0.293 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.025 | -0.025 | 0.045 | -0.048 |
02 | 0.043 | -0.517 | -0.323 | 0.492 |
03 | -4.382 | -0.744 | -4.523 | 1.253 |
04 | -6.962 | -6.962 | 1.386 | -6.962 |
05 | 1.385 | -6.962 | -5.805 | -6.962 |
06 | -6.962 | 1.386 | -6.962 | -6.962 |
07 | 1.311 | -6.962 | -1.248 | -6.962 |
08 | -0.977 | -0.891 | 1.022 | -0.831 |
09 | -1.123 | 0.468 | 0.562 | -1.126 |
10 | -0.819 | -0.079 | -0.719 | 0.764 |
11 | -0.577 | -0.273 | 0.535 | -0.031 |
12 | -0.3 | -0.232 | 0.258 | 0.158 |
P-value | Threshold |
---|---|
0.001 | 4.809515 |
0.0005 | 5.86275 |
0.0001 | 7.584505 |