Motif | MEIS2.H12CORE.0.P.C |
Gene (human) | MEIS2 (GeneCards) |
Gene synonyms (human) | MRG1 |
Gene (mouse) | Meis2 |
Gene synonyms (mouse) | Mrg1, Stra10 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | C |
Motif | MEIS2.H12CORE.0.P.C |
Gene (human) | MEIS2 (GeneCards) |
Gene synonyms (human) | MRG1 |
Gene (mouse) | Meis2 |
Gene synonyms (mouse) | Mrg1, Stra10 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | C |
Motif length | 13 |
Consensus | dWGAKWdAYKdbh |
GC content | 36.88% |
Information content (bits; total / per base) | 9.767 / 0.751 |
Data sources | ChIP-Seq |
Aligned words | 1000 |
ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
---|---|---|---|---|---|---|---|---|---|---|---|
Human | 1 (7) | 0.812 | 0.855 | 0.755 | 0.793 | 0.796 | 0.85 | 3.005 | 3.49 | 332.143 | 391.347 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 8 experiments | median | 0.587 | 0.548 | 0.566 | 0.54 | 0.549 | 0.531 |
best | 0.73 | 0.65 | 0.699 | 0.634 | 0.662 | 0.611 | |
Methyl HT-SELEX, 2 experiments | median | 0.587 | 0.548 | 0.566 | 0.54 | 0.549 | 0.531 |
best | 0.594 | 0.555 | 0.57 | 0.544 | 0.552 | 0.534 | |
Non-Methyl HT-SELEX, 6 experiments | median | 0.592 | 0.552 | 0.579 | 0.546 | 0.561 | 0.538 |
best | 0.73 | 0.65 | 0.699 | 0.634 | 0.662 | 0.611 |
rSNP benchmarking, ADASTRA | odds-ratio | -log-Fisher's P | Pearson r | Kendall tau |
---|---|---|---|---|
# | 3.031 | 1.887 | 0.069 | 0.1 |
rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
---|---|---|---|---|
batch 1 | 0.492 | 0.067 | 0.063 | 0.02 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Homeo domain factors {3.1} (TFClass) |
TF family | TALE-type HD {3.1.4} (TFClass) |
TF subfamily | MEIS {3.1.4.2} (TFClass) |
TFClass ID | TFClass: 3.1.4.2.2 |
HGNC | HGNC:7001 |
MGI | MGI:108564 |
EntrezGene (human) | GeneID:4212 (SSTAR profile) |
EntrezGene (mouse) | GeneID:17536 (SSTAR profile) |
UniProt ID (human) | MEIS2_HUMAN |
UniProt ID (mouse) | MEIS2_MOUSE |
UniProt AC (human) | O14770 (TFClass) |
UniProt AC (mouse) | P97367 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 1 human, 0 mouse |
HT-SELEX | 6 |
Methyl-HT-SELEX | 2 |
PCM | MEIS2.H12CORE.0.P.C.pcm |
PWM | MEIS2.H12CORE.0.P.C.pwm |
PFM | MEIS2.H12CORE.0.P.C.pfm |
Alignment | MEIS2.H12CORE.0.P.C.words.tsv |
Threshold to P-value map | MEIS2.H12CORE.0.P.C.thr |
Motif in other formats | |
JASPAR format | MEIS2.H12CORE.0.P.C_jaspar_format.txt |
MEME format | MEIS2.H12CORE.0.P.C_meme_format.meme |
Transfac format | MEIS2.H12CORE.0.P.C_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 390.0 | 138.0 | 278.0 | 194.0 |
02 | 222.0 | 5.0 | 43.0 | 730.0 |
03 | 51.0 | 4.0 | 916.0 | 29.0 |
04 | 963.0 | 6.0 | 24.0 | 7.0 |
05 | 45.0 | 112.0 | 114.0 | 729.0 |
06 | 142.0 | 13.0 | 110.0 | 735.0 |
07 | 235.0 | 39.0 | 303.0 | 423.0 |
08 | 956.0 | 12.0 | 29.0 | 3.0 |
09 | 13.0 | 153.0 | 88.0 | 746.0 |
10 | 151.0 | 51.0 | 581.0 | 217.0 |
11 | 310.0 | 65.0 | 485.0 | 140.0 |
12 | 93.0 | 462.0 | 274.0 | 171.0 |
13 | 181.0 | 338.0 | 151.0 | 330.0 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.39 | 0.138 | 0.278 | 0.194 |
02 | 0.222 | 0.005 | 0.043 | 0.73 |
03 | 0.051 | 0.004 | 0.916 | 0.029 |
04 | 0.963 | 0.006 | 0.024 | 0.007 |
05 | 0.045 | 0.112 | 0.114 | 0.729 |
06 | 0.142 | 0.013 | 0.11 | 0.735 |
07 | 0.235 | 0.039 | 0.303 | 0.423 |
08 | 0.956 | 0.012 | 0.029 | 0.003 |
09 | 0.013 | 0.153 | 0.088 | 0.746 |
10 | 0.151 | 0.051 | 0.581 | 0.217 |
11 | 0.31 | 0.065 | 0.485 | 0.14 |
12 | 0.093 | 0.462 | 0.274 | 0.171 |
13 | 0.181 | 0.338 | 0.151 | 0.33 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.442 | -0.589 | 0.105 | -0.252 |
02 | -0.118 | -3.622 | -1.728 | 1.067 |
03 | -1.563 | -3.783 | 1.294 | -2.103 |
04 | 1.344 | -3.484 | -2.281 | -3.362 |
05 | -1.684 | -0.795 | -0.777 | 1.066 |
06 | -0.56 | -2.839 | -0.812 | 1.074 |
07 | -0.061 | -1.821 | 0.191 | 0.523 |
08 | 1.336 | -2.909 | -2.103 | -3.975 |
09 | -2.839 | -0.487 | -1.032 | 1.089 |
10 | -0.5 | -1.563 | 0.839 | -0.141 |
11 | 0.214 | -1.328 | 0.659 | -0.574 |
12 | -0.977 | 0.611 | 0.091 | -0.377 |
13 | -0.32 | 0.3 | -0.5 | 0.276 |
P-value | Threshold |
---|---|
0.001 | 4.80221 |
0.0005 | 5.62901 |
0.0001 | 7.279615 |