MotifMEIS2.H12CORE.0.P.C
Gene (human)MEIS2
(GeneCards)
Gene synonyms (human)MRG1
Gene (mouse)Meis2
Gene synonyms (mouse)Mrg1, Stra10
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
C
Motif length13
ConsensusdWGAKWdAYKdbh
GC content36.88%
Information content (bits; total / per base)9.767 / 0.751
Data sourcesChIP-Seq
Aligned words1000

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (7) 0.812 0.855 0.755 0.793 0.796 0.85 3.005 3.49 332.143 391.347

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 8 experiments median 0.587 0.548 0.566 0.54 0.549 0.531
best 0.73 0.65 0.699 0.634 0.662 0.611
Methyl HT-SELEX, 2 experiments median 0.587 0.548 0.566 0.54 0.549 0.531
best 0.594 0.555 0.57 0.544 0.552 0.534
Non-Methyl HT-SELEX, 6 experiments median 0.592 0.552 0.579 0.546 0.561 0.538
best 0.73 0.65 0.699 0.634 0.662 0.611

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 3.031 1.887 0.069 0.1

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.492 0.067 0.063 0.02
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyTALE-type HD {3.1.4} (TFClass)
TF subfamilyMEIS {3.1.4.2} (TFClass)
TFClass IDTFClass: 3.1.4.2.2
HGNCHGNC:7001
MGIMGI:108564
EntrezGene (human)GeneID:4212
(SSTAR profile)
EntrezGene (mouse)GeneID:17536
(SSTAR profile)
UniProt ID (human)MEIS2_HUMAN
UniProt ID (mouse)MEIS2_MOUSE
UniProt AC (human)O14770
(TFClass)
UniProt AC (mouse)P97367
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 0 mouse
HT-SELEX 6
Methyl-HT-SELEX 2
PCM
ACGT
01390.0138.0278.0194.0
02222.05.043.0730.0
0351.04.0916.029.0
04963.06.024.07.0
0545.0112.0114.0729.0
06142.013.0110.0735.0
07235.039.0303.0423.0
08956.012.029.03.0
0913.0153.088.0746.0
10151.051.0581.0217.0
11310.065.0485.0140.0
1293.0462.0274.0171.0
13181.0338.0151.0330.0
PFM
ACGT
010.390.1380.2780.194
020.2220.0050.0430.73
030.0510.0040.9160.029
040.9630.0060.0240.007
050.0450.1120.1140.729
060.1420.0130.110.735
070.2350.0390.3030.423
080.9560.0120.0290.003
090.0130.1530.0880.746
100.1510.0510.5810.217
110.310.0650.4850.14
120.0930.4620.2740.171
130.1810.3380.1510.33
PWM
ACGT
010.442-0.5890.105-0.252
02-0.118-3.622-1.7281.067
03-1.563-3.7831.294-2.103
041.344-3.484-2.281-3.362
05-1.684-0.795-0.7771.066
06-0.56-2.839-0.8121.074
07-0.061-1.8210.1910.523
081.336-2.909-2.103-3.975
09-2.839-0.487-1.0321.089
10-0.5-1.5630.839-0.141
110.214-1.3280.659-0.574
12-0.9770.6110.091-0.377
13-0.320.3-0.50.276
Standard thresholds
P-value Threshold
0.001 4.80221
0.0005 5.62901
0.0001 7.279615