MEIS1.H12RSNP.1.PS.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MEIS1.H12RSNP.1.PS.D
Gene (human)	MEIS1 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Meis1
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	D

Motif length	11
Consensus	nnnWGACAKnh
GC content	51.7%
Information content (bits; total / per base)	7.522 / 0.684
Data sources	ChIP-Seq + HT-SELEX
Aligned words	996

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	3 (16)	0.687	0.708	0.536	0.577	0.61	0.642	1.465	1.693	28.181	74.886
Mouse	18 (114)	0.74	0.824	0.577	0.702	0.685	0.787	1.813	2.453	78.44	249.585

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 1 experiments	median	0.943	0.903	0.918	0.875	0.869	0.827
Non-Methyl HT-SELEX, 1 experiments	best	0.943	0.903	0.918	0.875	0.869	0.827

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	TALE-type HD {3.1.4} (TFClass)
TF subfamily	MEIS {3.1.4.2} (TFClass)
TFClass ID	TFClass: 3.1.4.2.1
HGNC	HGNC:7000
MGI	MGI:104717
EntrezGene (human)	GeneID:4211 (SSTAR profile)
EntrezGene (mouse)	GeneID:17268 (SSTAR profile)
UniProt ID (human)	MEIS1_HUMAN
UniProt ID (mouse)	MEIS1_MOUSE
UniProt AC (human)	O00470 (TFClass)
UniProt AC (mouse)	Q60954 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	3 human, 18 mouse
HT-SELEX	1
Methyl-HT-SELEX	0

PCM	MEIS1.H12RSNP.1.PS.D.pcm
PWM	MEIS1.H12RSNP.1.PS.D.pwm
PFM	MEIS1.H12RSNP.1.PS.D.pfm
Alignment	MEIS1.H12RSNP.1.PS.D.words.tsv
Threshold to P-value map	MEIS1.H12RSNP.1.PS.D.thr
Motif in other formats
JASPAR format	MEIS1.H12RSNP.1.PS.D_jaspar_format.txt
MEME format	MEIS1.H12RSNP.1.PS.D_meme_format.meme
Transfac format	MEIS1.H12RSNP.1.PS.D_transfac_format.txt
Homer format	MEIS1.H12RSNP.1.PS.D_homer_format_0.001.txt MEIS1.H12RSNP.1.PS.D_homer_format_0.0005.txt MEIS1.H12RSNP.1.PS.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	228.0	198.0	342.0	228.0
02	348.0	178.0	260.0	210.0
03	178.0	329.0	322.0	167.0
04	100.0	19.0	95.0	782.0
05	1.0	11.0	962.0	22.0
06	804.0	1.0	191.0	0.0
07	12.0	922.0	29.0	33.0
08	830.0	17.0	43.0	106.0
09	71.0	98.0	670.0	157.0
10	198.0	297.0	321.0	180.0
11	241.0	210.0	149.0	396.0

PFM

	A	C	G	T
01	0.229	0.199	0.343	0.229
02	0.349	0.179	0.261	0.211
03	0.179	0.33	0.323	0.168
04	0.1	0.019	0.095	0.785
05	0.001	0.011	0.966	0.022
06	0.807	0.001	0.192	0.0
07	0.012	0.926	0.029	0.033
08	0.833	0.017	0.043	0.106
09	0.071	0.098	0.673	0.158
10	0.199	0.298	0.322	0.181
11	0.242	0.211	0.15	0.398

PWM

	A	C	G	T
01	-0.087	-0.227	0.315	-0.087
02	0.333	-0.333	0.043	-0.169
03	-0.333	0.277	0.256	-0.396
04	-0.902	-2.493	-0.952	1.14
05	-4.522	-2.981	1.346	-2.358
06	1.167	-4.522	-0.263	-4.979
07	-2.905	1.304	-2.099	-1.977
08	1.199	-2.594	-1.724	-0.845
09	-1.238	-0.922	0.985	-0.457
10	-0.227	0.175	0.252	-0.322
11	-0.032	-0.169	-0.509	0.461

Standard thresholds

P-value	Threshold
0.001	5.18268
0.0005	5.774585
0.0001	7.111415