MEIS1.H12INVIVO.1.PS.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MEIS1.H12INVIVO.1.PS.A
Gene (human)	MEIS1 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Meis1
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	A

Motif length	11
Consensus	nnbTGACAKvh
GC content	53.21%
Information content (bits; total / per base)	8.733 / 0.794
Data sources	ChIP-Seq + HT-SELEX
Aligned words	855

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	3 (16)	0.676	0.695	0.521	0.563	0.595	0.63	1.429	1.677	28.006	74.409
Mouse	18 (114)	0.735	0.824	0.578	0.7	0.692	0.797	1.885	2.54	78.848	266.77

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 1 experiments	median	0.94	0.898	0.915	0.87	0.866	0.823
Non-Methyl HT-SELEX, 1 experiments	best	0.94	0.898	0.915	0.87	0.866	0.823

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	TALE-type HD {3.1.4} (TFClass)
TF subfamily	MEIS {3.1.4.2} (TFClass)
TFClass ID	TFClass: 3.1.4.2.1
HGNC	HGNC:7000
MGI	MGI:104717
EntrezGene (human)	GeneID:4211 (SSTAR profile)
EntrezGene (mouse)	GeneID:17268 (SSTAR profile)
UniProt ID (human)	MEIS1_HUMAN
UniProt ID (mouse)	MEIS1_MOUSE
UniProt AC (human)	O00470 (TFClass)
UniProt AC (mouse)	Q60954 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	3 human, 18 mouse
HT-SELEX	1
Methyl-HT-SELEX	0

PCM	MEIS1.H12INVIVO.1.PS.A.pcm
PWM	MEIS1.H12INVIVO.1.PS.A.pwm
PFM	MEIS1.H12INVIVO.1.PS.A.pfm
Alignment	MEIS1.H12INVIVO.1.PS.A.words.tsv
Threshold to P-value map	MEIS1.H12INVIVO.1.PS.A.thr
Motif in other formats
JASPAR format	MEIS1.H12INVIVO.1.PS.A_jaspar_format.txt
MEME format	MEIS1.H12INVIVO.1.PS.A_meme_format.meme
Transfac format	MEIS1.H12INVIVO.1.PS.A_transfac_format.txt
Homer format	MEIS1.H12INVIVO.1.PS.A_homer_format_0.001.txt MEIS1.H12INVIVO.1.PS.A_homer_format_0.0005.txt MEIS1.H12INVIVO.1.PS.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	141.0	198.0	308.0	208.0
02	300.0	177.0	246.0	132.0
03	67.0	345.0	294.0	149.0
04	102.0	15.0	46.0	692.0
05	1.0	6.0	848.0	0.0
06	734.0	0.0	121.0	0.0
07	8.0	813.0	6.0	28.0
08	772.0	2.0	8.0	73.0
09	57.0	75.0	600.0	123.0
10	176.0	288.0	284.0	107.0
11	178.0	174.0	150.0	353.0

PFM

	A	C	G	T
01	0.165	0.232	0.36	0.243
02	0.351	0.207	0.288	0.154
03	0.078	0.404	0.344	0.174
04	0.119	0.018	0.054	0.809
05	0.001	0.007	0.992	0.0
06	0.858	0.0	0.142	0.0
07	0.009	0.951	0.007	0.033
08	0.903	0.002	0.009	0.085
09	0.067	0.088	0.702	0.144
10	0.206	0.337	0.332	0.125
11	0.208	0.204	0.175	0.413

PWM

	A	C	G	T
01	-0.412	-0.076	0.363	-0.027
02	0.337	-0.187	0.139	-0.477
03	-1.143	0.476	0.317	-0.357
04	-0.731	-2.558	-1.508	1.169
05	-4.384	-3.333	1.372	-4.849
06	1.228	-4.849	-0.563	-4.849
07	-3.102	1.33	-3.333	-1.982
08	1.278	-4.068	-3.102	-1.059
09	-1.3	-1.033	1.027	-0.547
10	-0.193	0.296	0.282	-0.684
11	-0.181	-0.204	-0.351	0.499

Standard thresholds

P-value	Threshold
0.001	5.161755
0.0005	5.892175
0.0001	7.313675