MEIS1.H12INVIVO.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MEIS1.H12INVIVO.0.P.B
Gene (human)	MEIS1 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Meis1
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	12
Consensus	dTGATTKATKdb
GC content	30.61%
Information content (bits; total / per base)	11.12 / 0.927
Data sources	ChIP-Seq
Aligned words	1000

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	3 (16)	0.819	0.886	0.744	0.838	0.84	0.892	3.264	4.033	151.222	314.796
Mouse	18 (114)	0.823	0.9	0.729	0.832	0.827	0.902	2.957	3.651	179.194	412.456

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 1 experiments	median	0.618	0.578	0.586	0.558	0.56	0.543
Non-Methyl HT-SELEX, 1 experiments	best	0.618	0.578	0.586	0.558	0.56	0.543

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	TALE-type HD {3.1.4} (TFClass)
TF subfamily	MEIS {3.1.4.2} (TFClass)
TFClass ID	TFClass: 3.1.4.2.1
HGNC	HGNC:7000
MGI	MGI:104717
EntrezGene (human)	GeneID:4211 (SSTAR profile)
EntrezGene (mouse)	GeneID:17268 (SSTAR profile)
UniProt ID (human)	MEIS1_HUMAN
UniProt ID (mouse)	MEIS1_MOUSE
UniProt AC (human)	O00470 (TFClass)
UniProt AC (mouse)	Q60954 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	3 human, 18 mouse
HT-SELEX	1
Methyl-HT-SELEX	0

PCM	MEIS1.H12INVIVO.0.P.B.pcm
PWM	MEIS1.H12INVIVO.0.P.B.pwm
PFM	MEIS1.H12INVIVO.0.P.B.pfm
Alignment	MEIS1.H12INVIVO.0.P.B.words.tsv
Threshold to P-value map	MEIS1.H12INVIVO.0.P.B.thr
Motif in other formats
JASPAR format	MEIS1.H12INVIVO.0.P.B_jaspar_format.txt
MEME format	MEIS1.H12INVIVO.0.P.B_meme_format.meme
Transfac format	MEIS1.H12INVIVO.0.P.B_transfac_format.txt
Homer format	MEIS1.H12INVIVO.0.P.B_homer_format_0.001.txt MEIS1.H12INVIVO.0.P.B_homer_format_0.0005.txt MEIS1.H12INVIVO.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	466.0	100.0	249.0	185.0
02	189.0	3.0	20.0	788.0
03	63.0	2.0	920.0	15.0
04	989.0	2.0	7.0	2.0
05	53.0	55.0	58.0	834.0
06	106.0	7.0	87.0	800.0
07	165.0	41.0	241.0	553.0
08	973.0	7.0	13.0	7.0
09	20.0	98.0	31.0	851.0
10	144.0	34.0	523.0	299.0
11	285.0	58.0	461.0	196.0
12	116.0	410.0	246.0	228.0

PFM

	A	C	G	T
01	0.466	0.1	0.249	0.185
02	0.189	0.003	0.02	0.788
03	0.063	0.002	0.92	0.015
04	0.989	0.002	0.007	0.002
05	0.053	0.055	0.058	0.834
06	0.106	0.007	0.087	0.8
07	0.165	0.041	0.241	0.553
08	0.973	0.007	0.013	0.007
09	0.02	0.098	0.031	0.851
10	0.144	0.034	0.523	0.299
11	0.285	0.058	0.461	0.196
12	0.116	0.41	0.246	0.228

PWM

	A	C	G	T
01	0.62	-0.906	-0.004	-0.299
02	-0.278	-3.975	-2.45	1.143
03	-1.358	-4.213	1.298	-2.711
04	1.37	-4.213	-3.362	-4.213
05	-1.526	-1.49	-1.439	1.2
06	-0.849	-3.362	-1.043	1.158
07	-0.412	-1.774	-0.036	0.79
08	1.354	-3.362	-2.839	-3.362
09	-2.45	-0.926	-2.04	1.22
10	-0.547	-1.952	0.735	0.178
11	0.13	-1.439	0.609	-0.241
12	-0.76	0.492	-0.016	-0.091

Standard thresholds

P-value	Threshold
0.001	4.46001
0.0005	5.38963
0.0001	7.303575