MEIS1.H12INVITRO.1.PS.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MEIS1.H12INVITRO.1.PS.A
Gene (human)	MEIS1 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Meis1
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	A

Motif length	10
Consensus	nhTGACARvn
GC content	48.47%
Information content (bits; total / per base)	10.543 / 1.054
Data sources	ChIP-Seq + HT-SELEX
Aligned words	2378

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	3 (16)	0.681	0.725	0.534	0.574	0.594	0.633	1.35	1.431	41.001	93.921
Mouse	18 (114)	0.714	0.813	0.565	0.698	0.654	0.75	1.556	2.021	75.746	220.886

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 1 experiments	median	0.943	0.906	0.921	0.879	0.866	0.826
Non-Methyl HT-SELEX, 1 experiments	best	0.943	0.906	0.921	0.879	0.866	0.826

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	TALE-type HD {3.1.4} (TFClass)
TF subfamily	MEIS {3.1.4.2} (TFClass)
TFClass ID	TFClass: 3.1.4.2.1
HGNC	HGNC:7000
MGI	MGI:104717
EntrezGene (human)	GeneID:4211 (SSTAR profile)
EntrezGene (mouse)	GeneID:17268 (SSTAR profile)
UniProt ID (human)	MEIS1_HUMAN
UniProt ID (mouse)	MEIS1_MOUSE
UniProt AC (human)	O00470 (TFClass)
UniProt AC (mouse)	Q60954 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	3 human, 18 mouse
HT-SELEX	1
Methyl-HT-SELEX	0

PCM	MEIS1.H12INVITRO.1.PS.A.pcm
PWM	MEIS1.H12INVITRO.1.PS.A.pwm
PFM	MEIS1.H12INVITRO.1.PS.A.pfm
Alignment	MEIS1.H12INVITRO.1.PS.A.words.tsv
Threshold to P-value map	MEIS1.H12INVITRO.1.PS.A.thr
Motif in other formats
JASPAR format	MEIS1.H12INVITRO.1.PS.A_jaspar_format.txt
MEME format	MEIS1.H12INVITRO.1.PS.A_meme_format.meme
Transfac format	MEIS1.H12INVITRO.1.PS.A_transfac_format.txt
Homer format	MEIS1.H12INVITRO.1.PS.A_homer_format_0.001.txt MEIS1.H12INVITRO.1.PS.A_homer_format_0.0005.txt MEIS1.H12INVITRO.1.PS.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	544.25	761.25	500.25	572.25
02	598.25	722.25	206.25	851.25
03	67.0	5.0	8.0	2298.0
04	0.0	0.0	2378.0	0.0
05	2378.0	0.0	0.0	0.0
06	0.0	2378.0	0.0	0.0
07	2371.0	0.0	7.0	0.0
08	405.0	164.0	1414.0	395.0
09	337.0	778.0	990.0	273.0
10	419.25	715.25	499.25	744.25

PFM

	A	C	G	T
01	0.229	0.32	0.21	0.241
02	0.252	0.304	0.087	0.358
03	0.028	0.002	0.003	0.966
04	0.0	0.0	1.0	0.0
05	1.0	0.0	0.0	0.0
06	0.0	1.0	0.0	0.0
07	0.997	0.0	0.003	0.0
08	0.17	0.069	0.595	0.166
09	0.142	0.327	0.416	0.115
10	0.176	0.301	0.21	0.313

PWM

	A	C	G	T
01	-0.088	0.247	-0.172	-0.038
02	0.006	0.194	-1.053	0.358
03	-2.158	-4.453	-4.094	1.35
04	-5.726	-5.726	1.384	-5.726
05	1.384	-5.726	-5.726	-5.726
06	-5.726	1.384	-5.726	-5.726
07	1.381	-5.726	-4.2	-5.726
08	-0.382	-1.279	0.865	-0.407
09	-0.565	0.268	0.509	-0.774
10	-0.348	0.184	-0.174	0.224

Standard thresholds

P-value	Threshold
0.001	4.482635
0.0005	6.186265
0.0001	7.67648