MEIS1.H12INVITRO.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MEIS1.H12INVITRO.0.P.B
Gene (human)	MEIS1 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Meis1
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	12
Consensus	vnWGAYdRMWKd
GC content	42.87%
Information content (bits; total / per base)	8.504 / 0.709
Data sources	ChIP-Seq
Aligned words	981

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	3 (16)	0.72	0.769	0.569	0.62	0.655	0.699	1.712	1.888	53.769	114.959
Mouse	18 (114)	0.779	0.896	0.613	0.808	0.717	0.87	2.0	3.367	118.684	215.268

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 1 experiments	median	0.778	0.703	0.762	0.687	0.718	0.659
Non-Methyl HT-SELEX, 1 experiments	best	0.778	0.703	0.762	0.687	0.718	0.659

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	TALE-type HD {3.1.4} (TFClass)
TF subfamily	MEIS {3.1.4.2} (TFClass)
TFClass ID	TFClass: 3.1.4.2.1
HGNC	HGNC:7000
MGI	MGI:104717
EntrezGene (human)	GeneID:4211 (SSTAR profile)
EntrezGene (mouse)	GeneID:17268 (SSTAR profile)
UniProt ID (human)	MEIS1_HUMAN
UniProt ID (mouse)	MEIS1_MOUSE
UniProt AC (human)	O00470 (TFClass)
UniProt AC (mouse)	Q60954 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	3 human, 18 mouse
HT-SELEX	1
Methyl-HT-SELEX	0

PCM	MEIS1.H12INVITRO.0.P.B.pcm
PWM	MEIS1.H12INVITRO.0.P.B.pwm
PFM	MEIS1.H12INVITRO.0.P.B.pfm
Alignment	MEIS1.H12INVITRO.0.P.B.words.tsv
Threshold to P-value map	MEIS1.H12INVITRO.0.P.B.thr
Motif in other formats
JASPAR format	MEIS1.H12INVITRO.0.P.B_jaspar_format.txt
MEME format	MEIS1.H12INVITRO.0.P.B_meme_format.meme
Transfac format	MEIS1.H12INVITRO.0.P.B_transfac_format.txt
Homer format	MEIS1.H12INVITRO.0.P.B_homer_format_0.001.txt MEIS1.H12INVITRO.0.P.B_homer_format_0.0005.txt MEIS1.H12INVITRO.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	346.0	181.0	312.0	142.0
02	264.0	225.0	350.0	142.0
03	167.0	4.0	67.0	743.0
04	27.0	22.0	923.0	9.0
05	905.0	27.0	30.0	19.0
06	37.0	372.0	66.0	506.0
07	376.0	5.0	229.0	371.0
08	230.0	16.0	678.0	57.0
09	745.0	143.0	65.0	28.0
10	80.0	55.0	62.0	784.0
11	93.0	61.0	581.0	246.0
12	275.0	114.0	459.0	133.0

PFM

	A	C	G	T
01	0.353	0.185	0.318	0.145
02	0.269	0.229	0.357	0.145
03	0.17	0.004	0.068	0.757
04	0.028	0.022	0.941	0.009
05	0.923	0.028	0.031	0.019
06	0.038	0.379	0.067	0.516
07	0.383	0.005	0.233	0.378
08	0.234	0.016	0.691	0.058
09	0.759	0.146	0.066	0.029
10	0.082	0.056	0.063	0.799
11	0.095	0.062	0.592	0.251
12	0.28	0.116	0.468	0.136

PWM

	A	C	G	T
01	0.342	-0.301	0.239	-0.541
02	0.073	-0.086	0.354	-0.541
03	-0.381	-3.765	-1.279	1.104
04	-2.152	-2.343	1.32	-3.137
05	1.301	-2.152	-2.052	-2.478
06	-1.853	0.414	-1.294	0.721
07	0.425	-3.604	-0.068	0.412
08	-0.064	-2.634	1.012	-1.436
09	1.106	-0.534	-1.309	-2.117
10	-1.106	-1.471	-1.355	1.157
11	-0.958	-1.371	0.858	0.003
12	0.114	-0.758	0.624	-0.606

Standard thresholds

P-value	Threshold
0.001	4.96416
0.0005	5.691735
0.0001	7.16044