MotifMEIS1.H12CORE.1.PS.A
Gene (human)MEIS1
(GeneCards)
Gene synonyms (human)
Gene (mouse)Meis1
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
A
Motif length11
ConsensusnnnWGACAKnh
GC content51.7%
Information content (bits; total / per base)7.522 / 0.684
Data sourcesChIP-Seq + HT-SELEX
Aligned words996

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 3 (16) 0.687 0.708 0.536 0.577 0.61 0.642 1.465 1.693 28.181 74.886
Mouse 18 (114) 0.74 0.824 0.577 0.702 0.685 0.787 1.813 2.453 78.44 249.585

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Non-Methyl HT-SELEX, 1 experiments median 0.943 0.903 0.918 0.875 0.869 0.827
best 0.943 0.903 0.918 0.875 0.869 0.827
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyTALE-type HD {3.1.4} (TFClass)
TF subfamilyMEIS {3.1.4.2} (TFClass)
TFClass IDTFClass: 3.1.4.2.1
HGNCHGNC:7000
MGIMGI:104717
EntrezGene (human)GeneID:4211
(SSTAR profile)
EntrezGene (mouse)GeneID:17268
(SSTAR profile)
UniProt ID (human)MEIS1_HUMAN
UniProt ID (mouse)MEIS1_MOUSE
UniProt AC (human)O00470
(TFClass)
UniProt AC (mouse)Q60954
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 3 human, 18 mouse
HT-SELEX 1
Methyl-HT-SELEX 0
PCM
ACGT
01228.0198.0342.0228.0
02348.0178.0260.0210.0
03178.0329.0322.0167.0
04100.019.095.0782.0
051.011.0962.022.0
06804.01.0191.00.0
0712.0922.029.033.0
08830.017.043.0106.0
0971.098.0670.0157.0
10198.0297.0321.0180.0
11241.0210.0149.0396.0
PFM
ACGT
010.2290.1990.3430.229
020.3490.1790.2610.211
030.1790.330.3230.168
040.10.0190.0950.785
050.0010.0110.9660.022
060.8070.0010.1920.0
070.0120.9260.0290.033
080.8330.0170.0430.106
090.0710.0980.6730.158
100.1990.2980.3220.181
110.2420.2110.150.398
PWM
ACGT
01-0.087-0.2270.315-0.087
020.333-0.3330.043-0.169
03-0.3330.2770.256-0.396
04-0.902-2.493-0.9521.14
05-4.522-2.9811.346-2.358
061.167-4.522-0.263-4.979
07-2.9051.304-2.099-1.977
081.199-2.594-1.724-0.845
09-1.238-0.9220.985-0.457
10-0.2270.1750.252-0.322
11-0.032-0.169-0.5090.461
Standard thresholds
P-value Threshold
0.001 5.18268
0.0005 5.774585
0.0001 7.111415