MEIS1.H12CORE.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MEIS1.H12CORE.0.P.B
Gene (human)	MEIS1 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Meis1
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	13
Consensus	dTGATTKAYddbh
GC content	36.48%
Information content (bits; total / per base)	10.924 / 0.84
Data sources	ChIP-Seq
Aligned words	997

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	3 (16)	0.829	0.898	0.753	0.845	0.823	0.887	2.985	3.657	141.721	284.337
Mouse	18 (114)	0.843	0.908	0.733	0.833	0.822	0.895	2.837	3.462	175.181	464.678

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 1 experiments	median	0.676	0.627	0.63	0.593	0.594	0.57
Non-Methyl HT-SELEX, 1 experiments	best	0.676	0.627	0.63	0.593	0.594	0.57

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	TALE-type HD {3.1.4} (TFClass)
TF subfamily	MEIS {3.1.4.2} (TFClass)
TFClass ID	TFClass: 3.1.4.2.1
HGNC	HGNC:7000
MGI	MGI:104717
EntrezGene (human)	GeneID:4211 (SSTAR profile)
EntrezGene (mouse)	GeneID:17268 (SSTAR profile)
UniProt ID (human)	MEIS1_HUMAN
UniProt ID (mouse)	MEIS1_MOUSE
UniProt AC (human)	O00470 (TFClass)
UniProt AC (mouse)	Q60954 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	3 human, 18 mouse
HT-SELEX	1
Methyl-HT-SELEX	0

PCM	MEIS1.H12CORE.0.P.B.pcm
PWM	MEIS1.H12CORE.0.P.B.pwm
PFM	MEIS1.H12CORE.0.P.B.pfm
Alignment	MEIS1.H12CORE.0.P.B.words.tsv
Threshold to P-value map	MEIS1.H12CORE.0.P.B.thr
Motif in other formats
JASPAR format	MEIS1.H12CORE.0.P.B_jaspar_format.txt
MEME format	MEIS1.H12CORE.0.P.B_meme_format.meme
Transfac format	MEIS1.H12CORE.0.P.B_transfac_format.txt
Homer format	MEIS1.H12CORE.0.P.B_homer_format_0.001.txt MEIS1.H12CORE.0.P.B_homer_format_0.0005.txt MEIS1.H12CORE.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	370.0	137.0	285.0	205.0
02	125.0	4.0	52.0	816.0
03	62.0	6.0	914.0	15.0
04	989.0	2.0	2.0	4.0
05	18.0	55.0	124.0	800.0
06	53.0	3.0	101.0	840.0
07	107.0	28.0	408.0	454.0
08	961.0	4.0	31.0	1.0
09	15.0	253.0	37.0	692.0
10	264.0	31.0	491.0	211.0
11	229.0	64.0	540.0	164.0
12	122.0	435.0	250.0	190.0
13	169.0	317.0	154.0	357.0

PFM

	A	C	G	T
01	0.371	0.137	0.286	0.206
02	0.125	0.004	0.052	0.818
03	0.062	0.006	0.917	0.015
04	0.992	0.002	0.002	0.004
05	0.018	0.055	0.124	0.802
06	0.053	0.003	0.101	0.843
07	0.107	0.028	0.409	0.455
08	0.964	0.004	0.031	0.001
09	0.015	0.254	0.037	0.694
10	0.265	0.031	0.492	0.212
11	0.23	0.064	0.542	0.164
12	0.122	0.436	0.251	0.191
13	0.17	0.318	0.154	0.358

PWM

	A	C	G	T
01	0.393	-0.593	0.133	-0.194
02	-0.683	-3.78	-1.541	1.181
03	-1.371	-3.481	1.294	-2.708
04	1.373	-4.21	-4.21	-3.78
05	-2.543	-1.487	-0.691	1.161
06	-1.523	-3.972	-0.893	1.21
07	-0.837	-2.133	0.49	0.597
08	1.344	-3.78	-2.037	-4.522
09	-2.708	0.015	-1.869	1.017
10	0.057	-2.037	0.675	-0.165
11	-0.084	-1.34	0.769	-0.415
12	-0.707	0.554	0.003	-0.269
13	-0.385	0.239	-0.477	0.357

Standard thresholds

P-value	Threshold
0.001	4.52186
0.0005	5.45696
0.0001	7.33441