MotifMEF2D.H12INVITRO.1.M.C
Gene (human)MEF2D
(GeneCards)
Gene synonyms (human)
Gene (mouse)Mef2d
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
C
Motif length16
ConsensusnMYvdWTTWGGhWvvn
GC content42.47%
Information content (bits; total / per base)10.548 / 0.659
Data sourcesMethyl-HT-SELEX
Aligned words6470

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (7) 0.577 0.588 0.399 0.406 0.514 0.533 1.091 1.155 10.215 12.31
Mouse 8 (46) 0.603 0.637 0.409 0.455 0.519 0.578 1.1 1.311 30.452 45.796

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 3 experiments median 0.686 0.615 0.636 0.592 0.574 0.561
best 0.949 0.93 0.842 0.824 0.699 0.711
Methyl HT-SELEX, 1 experiments median 0.949 0.93 0.842 0.824 0.699 0.711
best 0.949 0.93 0.842 0.824 0.699 0.711
Non-Methyl HT-SELEX, 2 experiments median 0.627 0.579 0.589 0.56 0.547 0.54
best 0.686 0.615 0.636 0.592 0.574 0.561
TF superclassalpha-Helices exposed by beta-structures {5} (TFClass)
TF classMADS box factors {5.1} (TFClass)
TF familyRegulators of differentiation {5.1.1} (TFClass)
TF subfamilyMEF2 {5.1.1.1} (TFClass)
TFClass IDTFClass: 5.1.1.1.4
HGNCHGNC:6997
MGIMGI:99533
EntrezGene (human)GeneID:4209
(SSTAR profile)
EntrezGene (mouse)GeneID:17261
(SSTAR profile)
UniProt ID (human)MEF2D_HUMAN
UniProt ID (mouse)MEF2D_MOUSE
UniProt AC (human)Q14814
(TFClass)
UniProt AC (mouse)Q63943
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 8 mouse
HT-SELEX 2
Methyl-HT-SELEX 1
PCM
ACGT
011190.01215.01935.02130.0
021328.254112.25510.25519.25
03223.04344.0269.01634.0
042562.01758.01150.01000.0
052787.01109.01262.01312.0
064540.094.0386.01450.0
07709.028.067.05666.0
081989.05.073.04403.0
093122.020.00.03328.0
10354.05.06111.00.0
111.01.06468.00.0
123446.0894.0623.01507.0
134295.0435.0640.01100.0
142508.02028.01000.0934.0
151218.252368.251899.25984.25
161747.251220.251939.251563.25
PFM
ACGT
010.1840.1880.2990.329
020.2050.6360.0790.08
030.0340.6710.0420.253
040.3960.2720.1780.155
050.4310.1710.1950.203
060.7020.0150.060.224
070.110.0040.010.876
080.3070.0010.0110.681
090.4830.0030.00.514
100.0550.0010.9450.0
110.00.01.00.0
120.5330.1380.0960.233
130.6640.0670.0990.17
140.3880.3130.1550.144
150.1880.3660.2940.152
160.270.1890.30.242
PWM
ACGT
01-0.306-0.2860.1790.275
02-0.1970.932-1.151-1.133
03-1.9730.987-1.7870.01
040.4590.083-0.341-0.48
050.544-0.377-0.248-0.209
061.031-2.824-1.428-0.109
07-0.823-3.982-3.1531.253
080.206-5.417-3.071.001
090.657-4.29-6.6040.721
10-1.515-5.4171.328-6.604
11-6.229-6.2291.385-6.604
120.756-0.592-0.952-0.071
130.976-1.31-0.925-0.385
140.4380.226-0.48-0.548
15-0.2830.3810.16-0.496
160.077-0.2810.181-0.034
Standard thresholds
P-value Threshold
0.001 4.70911
0.0005 5.64171
0.0001 7.39816