MotifMEF2C.H12CORE.0.P.B
Gene (human)MEF2C
(GeneCards)
Gene synonyms (human)
Gene (mouse)Mef2c
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length14
ConsensusndbYTAWTTYWGKv
GC content35.61%
Information content (bits; total / per base)10.067 / 0.719
Data sourcesChIP-Seq
Aligned words848

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 2 (12) 0.751 0.858 0.652 0.768 0.779 0.887 2.719 3.392 126.926 248.523
Mouse 12 (78) 0.834 0.899 0.755 0.833 0.839 0.893 3.125 3.53 163.914 426.114

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.906 0.868 0.806 0.776 0.674 0.679
best 0.909 0.872 0.812 0.781 0.683 0.685
Methyl HT-SELEX, 1 experiments median 0.903 0.865 0.799 0.77 0.665 0.673
best 0.903 0.865 0.799 0.77 0.665 0.673
Non-Methyl HT-SELEX, 1 experiments median 0.909 0.872 0.812 0.781 0.683 0.685
best 0.909 0.872 0.812 0.781 0.683 0.685

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.801 0.136 0.852 0.636
batch 2 0.582 0.024 0.356 0.21
TF superclassalpha-Helices exposed by beta-structures {5} (TFClass)
TF classMADS box factors {5.1} (TFClass)
TF familyRegulators of differentiation {5.1.1} (TFClass)
TF subfamilyMEF2 {5.1.1.1} (TFClass)
TFClass IDTFClass: 5.1.1.1.3
HGNCHGNC:6996
MGIMGI:99458
EntrezGene (human)GeneID:4208
(SSTAR profile)
EntrezGene (mouse)GeneID:17260
(SSTAR profile)
UniProt ID (human)MEF2C_HUMAN
UniProt ID (mouse)MEF2C_MOUSE
UniProt AC (human)Q06413
(TFClass)
UniProt AC (mouse)Q8CFN5
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 2 human, 12 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
01233.0123.0205.0287.0
02236.061.0190.0361.0
0388.095.0292.0373.0
0433.0632.058.0125.0
056.0148.08.0686.0
06704.048.037.059.0
07128.047.014.0659.0
08133.013.027.0675.0
0938.079.015.0716.0
10119.0216.033.0480.0
11224.043.084.0497.0
12117.06.0710.015.0
1364.050.0630.0104.0
14396.0259.0105.088.0
PFM
ACGT
010.2750.1450.2420.338
020.2780.0720.2240.426
030.1040.1120.3440.44
040.0390.7450.0680.147
050.0070.1750.0090.809
060.830.0570.0440.07
070.1510.0550.0170.777
080.1570.0150.0320.796
090.0450.0930.0180.844
100.140.2550.0390.566
110.2640.0510.0990.586
120.1380.0070.8370.018
130.0750.0590.7430.123
140.4670.3050.1240.104
PWM
ACGT
010.094-0.539-0.0330.301
020.106-1.226-0.1090.529
03-0.868-0.7930.3180.562
04-1.8181.087-1.275-0.523
05-3.325-0.356-3.0941.169
061.195-1.459-1.709-1.259
07-0.499-1.479-2.6121.129
08-0.462-2.678-2.0081.153
09-1.684-0.974-2.551.212
10-0.5710.019-1.8180.813
110.055-1.565-0.9140.847
12-0.588-3.3251.203-2.55
13-1.18-1.4191.084-0.704
140.6210.199-0.695-0.868
Standard thresholds
P-value Threshold
0.001 4.68451
0.0005 5.48691
0.0001 7.15611