MotifMEF2B.H12CORE.1.SM.B
Gene (human)MEF2B
(GeneCards)
Gene synonyms (human)XMEF2
Gene (mouse)Mef2b
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length18
ConsensusnhGWTWCCWWAThbGGhh
GC content42.12%
Information content (bits; total / per base)15.516 / 0.862
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words7295

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 16 (100) 0.696 0.761 0.532 0.611 0.623 0.692 1.578 1.904 50.947 144.229

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 3 experiments median 0.98 0.974 0.91 0.896 0.787 0.785
best 0.999 0.998 0.988 0.985 0.918 0.914
Methyl HT-SELEX, 1 experiments median 0.999 0.998 0.988 0.985 0.918 0.914
best 0.999 0.998 0.988 0.985 0.918 0.914
Non-Methyl HT-SELEX, 2 experiments median 0.753 0.752 0.706 0.704 0.641 0.645
best 0.98 0.974 0.91 0.896 0.787 0.785

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 1.855 1.938 0.103 0.068

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.799 0.338 0.43 0.24
batch 2 0.778 0.365 0.585 0.467
TF superclassalpha-Helices exposed by beta-structures {5} (TFClass)
TF classMADS box factors {5.1} (TFClass)
TF familyRegulators of differentiation {5.1.1} (TFClass)
TF subfamilyMEF2 {5.1.1.1} (TFClass)
TFClass IDTFClass: 5.1.1.1.2
HGNCHGNC:6995
MGIMGI:104526
EntrezGene (human)GeneID:100271849
(SSTAR profile)
GeneID:4207
(SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)MEF2B_HUMAN
UniProt ID (mouse)MEF2B_MOUSE
UniProt AC (human)Q02080
(TFClass)
UniProt AC (mouse)O55087
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 16 human, 0 mouse
HT-SELEX 2
Methyl-HT-SELEX 1
PCM
ACGT
011829.51601.52325.51538.5
02716.02990.0553.03036.0
03218.0362.06537.0178.0
04807.0232.0441.05815.0
05362.091.0142.06700.0
065036.0132.0864.01263.0
071.07293.00.01.0
081.06993.02.0299.0
095079.0582.0443.01191.0
102419.0334.0311.04231.0
116175.011.027.01082.0
121433.0126.041.05695.0
132197.01178.0683.03237.0
14903.01050.01920.03422.0
151189.016.06042.048.0
16242.0128.06087.0838.0
172770.752405.75837.751280.75
183067.51390.51130.51706.5
PFM
ACGT
010.2510.220.3190.211
020.0980.410.0760.416
030.030.050.8960.024
040.1110.0320.060.797
050.050.0120.0190.918
060.690.0180.1180.173
070.01.00.00.0
080.00.9590.00.041
090.6960.080.0610.163
100.3320.0460.0430.58
110.8460.0020.0040.148
120.1960.0170.0060.781
130.3010.1610.0940.444
140.1240.1440.2630.469
150.1630.0020.8280.007
160.0330.0180.8340.115
170.380.330.1150.176
180.420.1910.1550.234
PWM
ACGT
010.003-0.130.243-0.17
02-0.9330.494-1.190.509
03-2.115-1.6121.276-2.316
04-0.814-2.054-1.4161.159
05-1.612-2.975-2.5391.3
061.015-2.61-0.746-0.367
07-6.3391.385-6.711-6.339
08-6.3391.343-6.069-1.802
091.023-1.14-1.411-0.425
100.282-1.692-1.7630.841
111.219-4.928-4.135-0.521
12-0.241-2.656-3.7431.138
130.186-0.436-0.980.573
14-0.702-0.5510.0510.629
15-0.427-4.6071.197-3.593
16-2.012-2.6411.204-0.776
170.4180.277-0.776-0.353
180.519-0.271-0.477-0.066
Standard thresholds
P-value Threshold
0.001 2.57061
0.0005 3.83511
0.0001 6.41411