MotifMCR.H12INVIVO.1.SM.D
Gene (human)NR3C2
(GeneCards)
Gene synonyms (human)MCR, MLR
Gene (mouse)Nr3c2
Gene synonyms (mouse)Mlr
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
D
Motif length9
ConsensusndYGTWCbn
GC content47.62%
Information content (bits; total / per base)6.726 / 0.747
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9404

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.881 0.826 0.816 0.769 0.749 0.717
best 0.919 0.867 0.91 0.855 0.891 0.835
Methyl HT-SELEX, 1 experiments median 0.919 0.867 0.91 0.855 0.891 0.835
best 0.919 0.867 0.91 0.855 0.891 0.835
Non-Methyl HT-SELEX, 3 experiments median 0.88 0.814 0.761 0.737 0.652 0.653
best 0.882 0.839 0.871 0.802 0.847 0.78
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classNuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF familySteroid hormone receptors {2.1.1} (TFClass)
TF subfamilyGR-like (NR3C) {2.1.1.1} (TFClass)
TFClass IDTFClass: 2.1.1.1.2
HGNCHGNC:7979
MGIMGI:99459
EntrezGene (human)GeneID:4306
(SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)MCR_HUMAN
UniProt ID (mouse)MCR_MOUSE
UniProt AC (human)P08235
(TFClass)
UniProt AC (mouse)Q8VII8
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
012401.252271.251728.253003.25
023675.51179.52696.51852.5
03749.02292.0343.06020.0
04654.056.08465.0229.0
050.01.03.09400.0
062822.0700.0514.05368.0
0730.09110.047.0217.0
08922.54109.51710.52661.5
091607.753456.751622.752716.75
PFM
ACGT
010.2550.2420.1840.319
020.3910.1250.2870.197
030.080.2440.0360.64
040.070.0060.90.024
050.00.00.01.0
060.30.0740.0550.571
070.0030.9690.0050.023
080.0980.4370.1820.283
090.1710.3680.1730.289
PWM
ACGT
010.021-0.034-0.3070.245
020.446-0.6890.137-0.238
03-1.142-0.025-1.9190.94
04-1.277-3.6981.28-2.32
05-6.936-6.574-6.0981.385
060.182-1.209-1.5170.825
07-4.2891.354-3.866-2.373
08-0.9340.558-0.3180.124
09-0.380.385-0.370.144
Standard thresholds
P-value Threshold
0.001 5.35271
0.0005 5.803535
0.0001 6.52913