MCR.H12INVITRO.1.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MCR.H12INVITRO.1.SM.B
Gene (human)	NR3C2 (GeneCards)
Gene synonyms (human)	MCR, MLR
Gene (mouse)	Nr3c2
Gene synonyms (mouse)	Mlr
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	9
Consensus	ndYGTWCbn
GC content	47.62%
Information content (bits; total / per base)	6.726 / 0.747
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	9404

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.881	0.826	0.816	0.769	0.749	0.717
Overall, 4 experiments	best	0.919	0.867	0.91	0.855	0.891	0.835
Methyl HT-SELEX, 1 experiments	median	0.919	0.867	0.91	0.855	0.891	0.835
Methyl HT-SELEX, 1 experiments	best	0.919	0.867	0.91	0.855	0.891	0.835
Non-Methyl HT-SELEX, 3 experiments	median	0.88	0.814	0.761	0.737	0.652	0.653
Non-Methyl HT-SELEX, 3 experiments	best	0.882	0.839	0.871	0.802	0.847	0.78

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	Nuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF family	Steroid hormone receptors {2.1.1} (TFClass)
TF subfamily	GR-like (NR3C) {2.1.1.1} (TFClass)
TFClass ID	TFClass: 2.1.1.1.2
HGNC	HGNC:7979
MGI	MGI:99459
EntrezGene (human)	GeneID:4306 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	MCR_HUMAN
UniProt ID (mouse)	MCR_MOUSE
UniProt AC (human)	P08235 (TFClass)
UniProt AC (mouse)	Q8VII8 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	3
Methyl-HT-SELEX	1

PCM	MCR.H12INVITRO.1.SM.B.pcm
PWM	MCR.H12INVITRO.1.SM.B.pwm
PFM	MCR.H12INVITRO.1.SM.B.pfm
Alignment	MCR.H12INVITRO.1.SM.B.words.tsv
Threshold to P-value map	MCR.H12INVITRO.1.SM.B.thr
Motif in other formats
JASPAR format	MCR.H12INVITRO.1.SM.B_jaspar_format.txt
MEME format	MCR.H12INVITRO.1.SM.B_meme_format.meme
Transfac format	MCR.H12INVITRO.1.SM.B_transfac_format.txt
Homer format	MCR.H12INVITRO.1.SM.B_homer_format_0.001.txt MCR.H12INVITRO.1.SM.B_homer_format_0.0005.txt MCR.H12INVITRO.1.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2401.25	2271.25	1728.25	3003.25
02	3675.5	1179.5	2696.5	1852.5
03	749.0	2292.0	343.0	6020.0
04	654.0	56.0	8465.0	229.0
05	0.0	1.0	3.0	9400.0
06	2822.0	700.0	514.0	5368.0
07	30.0	9110.0	47.0	217.0
08	922.5	4109.5	1710.5	2661.5
09	1607.75	3456.75	1622.75	2716.75

PFM

	A	C	G	T
01	0.255	0.242	0.184	0.319
02	0.391	0.125	0.287	0.197
03	0.08	0.244	0.036	0.64
04	0.07	0.006	0.9	0.024
05	0.0	0.0	0.0	1.0
06	0.3	0.074	0.055	0.571
07	0.003	0.969	0.005	0.023
08	0.098	0.437	0.182	0.283
09	0.171	0.368	0.173	0.289

PWM

	A	C	G	T
01	0.021	-0.034	-0.307	0.245
02	0.446	-0.689	0.137	-0.238
03	-1.142	-0.025	-1.919	0.94
04	-1.277	-3.698	1.28	-2.32
05	-6.936	-6.574	-6.098	1.385
06	0.182	-1.209	-1.517	0.825
07	-4.289	1.354	-3.866	-2.373
08	-0.934	0.558	-0.318	0.124
09	-0.38	0.385	-0.37	0.144

Standard thresholds

P-value	Threshold
0.001	5.35271
0.0005	5.803535
0.0001	6.52913