| Motif | MCR.H12CORE.1.SM.B |
| Gene (human) | NR3C2 (GeneCards) |
| Gene synonyms (human) | MCR, MLR |
| Gene (mouse) | Nr3c2 |
| Gene synonyms (mouse) | Mlr |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 1 |
| Quality | B |
| Motif | MCR.H12CORE.1.SM.B |
| Gene (human) | NR3C2 (GeneCards) |
| Gene synonyms (human) | MCR, MLR |
| Gene (mouse) | Nr3c2 |
| Gene synonyms (mouse) | Mlr |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 1 |
| Quality | B |
| Motif length | 9 |
| Consensus | ndYGTWCbn |
| GC content | 47.62% |
| Information content (bits; total / per base) | 6.726 / 0.747 |
| Data sources | HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 9404 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 4 experiments | median | 0.881 | 0.826 | 0.816 | 0.769 | 0.749 | 0.717 |
| best | 0.919 | 0.867 | 0.91 | 0.855 | 0.891 | 0.835 | |
| Methyl HT-SELEX, 1 experiments | median | 0.919 | 0.867 | 0.91 | 0.855 | 0.891 | 0.835 |
| best | 0.919 | 0.867 | 0.91 | 0.855 | 0.891 | 0.835 | |
| Non-Methyl HT-SELEX, 3 experiments | median | 0.88 | 0.814 | 0.761 | 0.737 | 0.652 | 0.653 |
| best | 0.882 | 0.839 | 0.871 | 0.802 | 0.847 | 0.78 | |
| TF superclass | Zinc-coordinating DNA-binding domains {2} (TFClass) |
| TF class | Nuclear receptors with C4 zinc fingers {2.1} (TFClass) |
| TF family | Steroid hormone receptors {2.1.1} (TFClass) |
| TF subfamily | GR-like (NR3C) {2.1.1.1} (TFClass) |
| TFClass ID | TFClass: 2.1.1.1.2 |
| HGNC | HGNC:7979 |
| MGI | MGI:99459 |
| EntrezGene (human) | GeneID:4306 (SSTAR profile) |
| EntrezGene (mouse) | |
| UniProt ID (human) | MCR_HUMAN |
| UniProt ID (mouse) | MCR_MOUSE |
| UniProt AC (human) | P08235 (TFClass) |
| UniProt AC (mouse) | Q8VII8 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 0 mouse |
| HT-SELEX | 3 |
| Methyl-HT-SELEX | 1 |
| PCM | MCR.H12CORE.1.SM.B.pcm |
| PWM | MCR.H12CORE.1.SM.B.pwm |
| PFM | MCR.H12CORE.1.SM.B.pfm |
| Alignment | MCR.H12CORE.1.SM.B.words.tsv |
| Threshold to P-value map | MCR.H12CORE.1.SM.B.thr |
| Motif in other formats | |
| JASPAR format | MCR.H12CORE.1.SM.B_jaspar_format.txt |
| MEME format | MCR.H12CORE.1.SM.B_meme_format.meme |
| Transfac format | MCR.H12CORE.1.SM.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 2401.25 | 2271.25 | 1728.25 | 3003.25 |
| 02 | 3675.5 | 1179.5 | 2696.5 | 1852.5 |
| 03 | 749.0 | 2292.0 | 343.0 | 6020.0 |
| 04 | 654.0 | 56.0 | 8465.0 | 229.0 |
| 05 | 0.0 | 1.0 | 3.0 | 9400.0 |
| 06 | 2822.0 | 700.0 | 514.0 | 5368.0 |
| 07 | 30.0 | 9110.0 | 47.0 | 217.0 |
| 08 | 922.5 | 4109.5 | 1710.5 | 2661.5 |
| 09 | 1607.75 | 3456.75 | 1622.75 | 2716.75 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.255 | 0.242 | 0.184 | 0.319 |
| 02 | 0.391 | 0.125 | 0.287 | 0.197 |
| 03 | 0.08 | 0.244 | 0.036 | 0.64 |
| 04 | 0.07 | 0.006 | 0.9 | 0.024 |
| 05 | 0.0 | 0.0 | 0.0 | 1.0 |
| 06 | 0.3 | 0.074 | 0.055 | 0.571 |
| 07 | 0.003 | 0.969 | 0.005 | 0.023 |
| 08 | 0.098 | 0.437 | 0.182 | 0.283 |
| 09 | 0.171 | 0.368 | 0.173 | 0.289 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.021 | -0.034 | -0.307 | 0.245 |
| 02 | 0.446 | -0.689 | 0.137 | -0.238 |
| 03 | -1.142 | -0.025 | -1.919 | 0.94 |
| 04 | -1.277 | -3.698 | 1.28 | -2.32 |
| 05 | -6.936 | -6.574 | -6.098 | 1.385 |
| 06 | 0.182 | -1.209 | -1.517 | 0.825 |
| 07 | -4.289 | 1.354 | -3.866 | -2.373 |
| 08 | -0.934 | 0.558 | -0.318 | 0.124 |
| 09 | -0.38 | 0.385 | -0.37 | 0.144 |
| P-value | Threshold |
|---|---|
| 0.001 | 5.35271 |
| 0.0005 | 5.803535 |
| 0.0001 | 6.52913 |