MotifMCR.H12CORE.0.S.B
Gene (human)NR3C2
(GeneCards)
Gene synonyms (human)MCR, MLR
Gene (mouse)Nr3c2
Gene synonyms (mouse)Mlr
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length17
ConsensusnRGdACAhARTGThCYn
GC content44.48%
Information content (bits; total / per base)18.23 / 1.072
Data sourcesHT-SELEX
Aligned words9484

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.968 0.95 0.856 0.849 0.764 0.763
best 0.982 0.978 0.962 0.945 0.91 0.889
Methyl HT-SELEX, 1 experiments median 0.982 0.971 0.962 0.945 0.91 0.889
best 0.982 0.971 0.962 0.945 0.91 0.889
Non-Methyl HT-SELEX, 3 experiments median 0.958 0.929 0.78 0.8 0.649 0.681
best 0.979 0.978 0.931 0.898 0.88 0.845
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classNuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF familySteroid hormone receptors {2.1.1} (TFClass)
TF subfamilyGR-like (NR3C) {2.1.1.1} (TFClass)
TFClass IDTFClass: 2.1.1.1.2
HGNCHGNC:7979
MGIMGI:99459
EntrezGene (human)GeneID:4306
(SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)MCR_HUMAN
UniProt ID (mouse)MCR_MOUSE
UniProt AC (human)P08235
(TFClass)
UniProt AC (mouse)Q8VII8
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
012171.751677.753405.752228.75
023651.0488.04604.0741.0
0382.020.09345.037.0
044812.0553.01522.02597.0
059426.021.016.021.0
0620.09425.017.022.0
078682.022.0594.0186.0
082119.03450.0954.02961.0
096788.00.02696.00.0
106517.0526.01415.01026.0
11233.0325.029.08897.0
1226.07.09444.07.0
1316.08.06.09454.0
142887.01630.0345.04622.0
1534.09370.014.066.0
16848.754548.75446.753639.75
172799.03050.01734.01901.0
PFM
ACGT
010.2290.1770.3590.235
020.3850.0510.4850.078
030.0090.0020.9850.004
040.5070.0580.160.274
050.9940.0020.0020.002
060.0020.9940.0020.002
070.9150.0020.0630.02
080.2230.3640.1010.312
090.7160.00.2840.0
100.6870.0550.1490.108
110.0250.0340.0030.938
120.0030.0010.9960.001
130.0020.0010.0010.997
140.3040.1720.0360.487
150.0040.9880.0010.007
160.0890.480.0470.384
170.2950.3220.1830.2
PWM
ACGT
01-0.088-0.3450.362-0.062
020.431-1.5770.663-1.161
03-3.338-4.6681.371-4.101
040.707-1.453-0.4430.091
051.379-4.624-4.866-4.624
06-4.6681.379-4.812-4.582
071.297-4.582-1.381-2.534
08-0.1120.375-0.9090.222
091.051-6.9440.128-6.944
101.01-1.502-0.516-0.836
11-2.311-1.981-4.3291.322
12-4.43-5.5431.381-5.543
13-4.866-5.441-5.6571.382
140.197-0.374-1.9220.667
15-4.1811.373-4.982-3.548
16-1.0260.651-1.6650.428
170.1660.252-0.313-0.221
Standard thresholds
P-value Threshold
0.001 -0.71054
0.0005 0.96651
0.0001 4.52496