MBNL2.H12CORE.0.S.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MBNL2.H12CORE.0.S.C
Gene (human)	MBNL2 (GeneCards)
Gene synonyms (human)	MBLL, MBLL39, MLP1
Gene (mouse)	Mbnl2
Gene synonyms (mouse)	Kiaa4072
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	C

Motif length	14
Consensus	nhYhCGCTTYvbbb
GC content	55.14%
Information content (bits; total / per base)	11.125 / 0.795
Data sources	HT-SELEX
Aligned words	6395

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 1 experiments	median	0.86	0.792	0.82	0.756	0.755	0.707
Non-Methyl HT-SELEX, 1 experiments	best	0.86	0.792	0.82	0.756	0.755	0.707

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.71	0.335	0.511	0.205
batch 2	0.605	0.168	0.412	0.329

TF superclass	Yet undefined DNA-binding domains {0} (TFClass)
TF class	Uncharacterized {0.0} (TFClass)
TF family	Unannotated {0.0.9} (TFClass)
TF subfamily	{0.0.9.0} (TFClass)
TFClass ID	TFClass: 0.0.9.0.6
HGNC	HGNC:16746
MGI	MGI:2145597
EntrezGene (human)	GeneID:10150 (SSTAR profile)
EntrezGene (mouse)	GeneID:105559 (SSTAR profile)
UniProt ID (human)	MBNL2_HUMAN
UniProt ID (mouse)	MBNL2_MOUSE
UniProt AC (human)	Q5VZF2 (TFClass)
UniProt AC (mouse)	Q8C181 (TFClass)
GRECO-DB-TF	no

ChIP-Seq	0 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	0

PCM	MBNL2.H12CORE.0.S.C.pcm
PWM	MBNL2.H12CORE.0.S.C.pwm
PFM	MBNL2.H12CORE.0.S.C.pfm
Alignment	MBNL2.H12CORE.0.S.C.words.tsv
Threshold to P-value map	MBNL2.H12CORE.0.S.C.thr
Motif in other formats
JASPAR format	MBNL2.H12CORE.0.S.C_jaspar_format.txt
MEME format	MBNL2.H12CORE.0.S.C_meme_format.meme
Transfac format	MBNL2.H12CORE.0.S.C_transfac_format.txt
Homer format	MBNL2.H12CORE.0.S.C_homer_format_0.001.txt MBNL2.H12CORE.0.S.C_homer_format_0.0005.txt MBNL2.H12CORE.0.S.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1253.25	2256.25	1250.25	1635.25
02	1076.5	2544.5	634.5	2139.5
03	1212.0	2601.0	61.0	2521.0
04	2256.0	1003.0	196.0	2940.0
05	74.0	4849.0	1.0	1471.0
06	0.0	0.0	6395.0	0.0
07	0.0	6395.0	0.0	0.0
08	0.0	842.0	0.0	5553.0
09	0.0	0.0	0.0	6395.0
10	797.0	4556.0	4.0	1038.0
11	1166.0	2743.0	1930.0	556.0
12	734.0	3412.0	937.0	1312.0
13	906.75	2400.75	1083.75	2003.75
14	1015.5	2172.5	1101.5	2105.5

PFM

	A	C	G	T
01	0.196	0.353	0.196	0.256
02	0.168	0.398	0.099	0.335
03	0.19	0.407	0.01	0.394
04	0.353	0.157	0.031	0.46
05	0.012	0.758	0.0	0.23
06	0.0	0.0	1.0	0.0
07	0.0	1.0	0.0	0.0
08	0.0	0.132	0.0	0.868
09	0.0	0.0	0.0	1.0
10	0.125	0.712	0.001	0.162
11	0.182	0.429	0.302	0.087
12	0.115	0.534	0.147	0.205
13	0.142	0.375	0.169	0.313
14	0.159	0.34	0.172	0.329

PWM

	A	C	G	T
01	-0.243	0.344	-0.245	0.023
02	-0.395	0.464	-0.922	0.291
03	-0.277	0.486	-3.232	0.455
04	0.344	-0.465	-2.089	0.609
05	-3.045	1.109	-6.218	-0.083
06	-6.594	-6.594	1.385	-6.594
07	-6.594	1.385	-6.594	-6.594
08	-6.594	-0.64	-6.594	1.244
09	-6.594	-6.594	-6.594	1.385
10	-0.695	1.046	-5.555	-0.431
11	-0.315	0.539	0.188	-1.054
12	-0.777	0.757	-0.533	-0.197
13	-0.566	0.406	-0.388	0.226
14	-0.453	0.306	-0.372	0.275

Standard thresholds

P-value	Threshold
0.001	4.49506
0.0005	5.73411
0.0001	7.61441