MAX.H12RSNP.0.PS.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MAX.H12RSNP.0.PS.A
Gene (human)	MAX (GeneCards)
Gene synonyms (human)	BHLHD4
Gene (mouse)	Max
Gene synonyms (mouse)	Myn
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	10
Consensus	vCACGTGGbb
GC content	71.52%
Information content (bits; total / per base)	12.007 / 1.201
Data sources	ChIP-Seq + HT-SELEX
Aligned words	1000

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	39 (261)	0.89	0.964	0.803	0.917	0.823	0.923	2.777	3.452	274.699	643.602
Mouse	6 (39)	0.875	0.932	0.779	0.872	0.812	0.874	2.598	3.099	219.456	500.62

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 6 experiments	median	0.989	0.98	0.984	0.973	0.96	0.95
Overall, 6 experiments	best	0.997	0.995	0.995	0.992	0.991	0.984
Methyl HT-SELEX, 1 experiments	median	0.934	0.887	0.922	0.873	0.887	0.84
Methyl HT-SELEX, 1 experiments	best	0.934	0.887	0.922	0.873	0.887	0.84
Non-Methyl HT-SELEX, 5 experiments	median	0.994	0.989	0.986	0.979	0.962	0.956
Non-Methyl HT-SELEX, 5 experiments	best	0.997	0.995	0.995	0.992	0.991	0.984

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	31.332	25.123	0.283	0.252

TF superclass	Basic domains {1} (TFClass)
TF class	Basic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF family	bHLH-ZIP {1.2.6} (TFClass)
TF subfamily	MYC {1.2.6.5} (TFClass)
TFClass ID	TFClass: 1.2.6.5.5
HGNC	HGNC:6913
MGI	MGI:96921
EntrezGene (human)	GeneID:4149 (SSTAR profile)
EntrezGene (mouse)	GeneID:17187 (SSTAR profile)
UniProt ID (human)	MAX_HUMAN
UniProt ID (mouse)	MAX_MOUSE
UniProt AC (human)	P61244 (TFClass)
UniProt AC (mouse)	P28574 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	39 human, 6 mouse
HT-SELEX	5
Methyl-HT-SELEX	1

PCM	MAX.H12RSNP.0.PS.A.pcm
PWM	MAX.H12RSNP.0.PS.A.pwm
PFM	MAX.H12RSNP.0.PS.A.pfm
Alignment	MAX.H12RSNP.0.PS.A.words.tsv
Threshold to P-value map	MAX.H12RSNP.0.PS.A.thr
Motif in other formats
JASPAR format	MAX.H12RSNP.0.PS.A_jaspar_format.txt
MEME format	MAX.H12RSNP.0.PS.A_meme_format.meme
Transfac format	MAX.H12RSNP.0.PS.A_transfac_format.txt
Homer format	MAX.H12RSNP.0.PS.A_homer_format_0.001.txt MAX.H12RSNP.0.PS.A_homer_format_0.0005.txt MAX.H12RSNP.0.PS.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	190.0	220.0	509.0	81.0
02	8.0	991.0	1.0	0.0
03	987.0	2.0	7.0	4.0
04	6.0	953.0	18.0	23.0
05	48.0	7.0	945.0	0.0
06	59.0	124.0	2.0	815.0
07	0.0	2.0	992.0	6.0
08	53.0	133.0	802.0	12.0
09	63.0	452.0	243.0	242.0
10	82.0	485.0	264.0	169.0

PFM

	A	C	G	T
01	0.19	0.22	0.509	0.081
02	0.008	0.991	0.001	0.0
03	0.987	0.002	0.007	0.004
04	0.006	0.953	0.018	0.023
05	0.048	0.007	0.945	0.0
06	0.059	0.124	0.002	0.815
07	0.0	0.002	0.992	0.006
08	0.053	0.133	0.802	0.012
09	0.063	0.452	0.243	0.242
10	0.082	0.485	0.264	0.169

PWM

	A	C	G	T
01	-0.272	-0.127	0.707	-1.113
02	-3.253	1.372	-4.525	-4.982
03	1.368	-4.213	-3.362	-3.783
04	-3.484	1.333	-2.546	-2.32
05	-1.622	-3.362	1.325	-4.982
06	-1.422	-0.694	-4.213	1.177
07	-4.982	-4.213	1.373	-3.484
08	-1.526	-0.625	1.161	-2.909
09	-1.358	0.589	-0.028	-0.032
10	-1.101	0.659	0.054	-0.388

Standard thresholds

P-value	Threshold
0.001	3.944015
0.0005	5.030535
0.0001	7.428515