MotifMAX.H12INVIVO.2.S.C
Gene (human)MAX
(GeneCards)
Gene synonyms (human)BHLHD4
Gene (mouse)Max
Gene synonyms (mouse)Myn
LOGO
LOGO (reverse complement)
Motif subtype2
Quality
C
Motif length25
ConsensusnbMMSKKKnhhdSCACGTGvbnnnn
GC content57.9%
Information content (bits; total / per base)18.076 / 0.723
Data sourcesHT-SELEX
Aligned words267

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 39 (261) 0.833 0.949 0.75 0.908 0.756 0.887 2.464 3.323 141.26 455.921
Mouse 6 (39) 0.828 0.9 0.736 0.852 0.749 0.83 2.387 2.941 128.886 365.119

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 6 experiments median 0.996 0.994 0.982 0.978 0.911 0.89
best 1.0 0.999 0.999 0.998 0.996 0.995
Methyl HT-SELEX, 1 experiments median 0.959 0.94 0.924 0.895 0.862 0.831
best 0.959 0.94 0.924 0.895 0.862 0.831
Non-Methyl HT-SELEX, 5 experiments median 0.997 0.996 0.988 0.982 0.96 0.949
best 1.0 0.999 0.999 0.998 0.996 0.995

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 28.632 23.366 0.287 0.253
TF superclassBasic domains {1} (TFClass)
TF classBasic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF familybHLH-ZIP {1.2.6} (TFClass)
TF subfamilyMYC {1.2.6.5} (TFClass)
TFClass IDTFClass: 1.2.6.5.5
HGNCHGNC:6913
MGIMGI:96921
EntrezGene (human)GeneID:4149
(SSTAR profile)
EntrezGene (mouse)GeneID:17187
(SSTAR profile)
UniProt ID (human)MAX_HUMAN
UniProt ID (mouse)MAX_MOUSE
UniProt AC (human)P61244
(TFClass)
UniProt AC (mouse)P28574
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 39 human, 6 mouse
HT-SELEX 5
Methyl-HT-SELEX 1
PCM
ACGT
0173.2568.2574.2551.25
0240.0127.054.046.0
0370.0165.021.011.0
04168.054.034.011.0
053.0185.062.017.0
069.09.0195.054.0
079.031.046.0181.0
0810.017.0208.032.0
0960.086.053.068.0
1070.050.040.0107.0
11112.042.033.080.0
12115.045.059.048.0
1314.0149.068.036.0
140.0267.00.00.0
15267.00.00.00.0
160.0267.00.00.0
170.00.0267.00.0
180.01.00.0266.0
190.00.0266.01.0
2059.077.0108.023.0
2129.055.031.0152.0
2259.077.037.094.0
2360.092.047.068.0
2463.25103.2548.2552.25
2559.585.560.561.5
PFM
ACGT
010.2740.2560.2780.192
020.150.4760.2020.172
030.2620.6180.0790.041
040.6290.2020.1270.041
050.0110.6930.2320.064
060.0340.0340.730.202
070.0340.1160.1720.678
080.0370.0640.7790.12
090.2250.3220.1990.255
100.2620.1870.150.401
110.4190.1570.1240.3
120.4310.1690.2210.18
130.0520.5580.2550.135
140.01.00.00.0
151.00.00.00.0
160.01.00.00.0
170.00.01.00.0
180.00.0040.00.996
190.00.00.9960.004
200.2210.2880.4040.086
210.1090.2060.1160.569
220.2210.2880.1390.352
230.2250.3450.1760.255
240.2370.3870.1810.196
250.2230.320.2270.23
PWM
ACGT
010.0910.0220.104-0.258
02-0.4980.633-0.207-0.363
030.0470.893-1.113-1.704
040.911-0.207-0.655-1.704
05-2.7411.006-0.072-1.309
06-1.88-1.881.058-0.207
07-1.88-0.744-0.3630.985
08-1.788-1.3091.123-0.713
09-0.1040.249-0.2250.018
100.047-0.282-0.4980.464
110.509-0.451-0.6840.178
120.535-0.384-0.121-0.322
13-1.4880.7920.018-0.6
14-3.8871.371-3.887-3.887
151.371-3.887-3.887-3.887
16-3.8871.371-3.887-3.887
17-3.887-3.8871.371-3.887
18-3.887-3.348-3.8871.367
19-3.887-3.8871.367-3.348
20-0.1210.140.473-1.027
21-0.807-0.189-0.7440.811
22-0.1210.14-0.5740.336
23-0.1040.315-0.3420.018
24-0.0530.429-0.317-0.239
25-0.1120.243-0.096-0.08
Standard thresholds
P-value Threshold
0.001 1.49111
0.0005 2.86351
0.0001 5.73281