| Motif | MAX.H12INVIVO.2.S.C |
| Gene (human) | MAX (GeneCards) |
| Gene synonyms (human) | BHLHD4 |
| Gene (mouse) | Max |
| Gene synonyms (mouse) | Myn |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 2 |
| Quality | C |
| Motif | MAX.H12INVIVO.2.S.C |
| Gene (human) | MAX (GeneCards) |
| Gene synonyms (human) | BHLHD4 |
| Gene (mouse) | Max |
| Gene synonyms (mouse) | Myn |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 2 |
| Quality | C |
| Motif length | 25 |
| Consensus | nbMMSKKKnhhdSCACGTGvbnnnn |
| GC content | 57.9% |
| Information content (bits; total / per base) | 18.076 / 0.723 |
| Data sources | HT-SELEX |
| Aligned words | 267 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 39 (261) | 0.833 | 0.949 | 0.75 | 0.908 | 0.756 | 0.887 | 2.464 | 3.323 | 141.26 | 455.921 |
| Mouse | 6 (39) | 0.828 | 0.9 | 0.736 | 0.852 | 0.749 | 0.83 | 2.387 | 2.941 | 128.886 | 365.119 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 6 experiments | median | 0.996 | 0.994 | 0.982 | 0.978 | 0.911 | 0.89 |
| best | 1.0 | 0.999 | 0.999 | 0.998 | 0.996 | 0.995 | |
| Methyl HT-SELEX, 1 experiments | median | 0.959 | 0.94 | 0.924 | 0.895 | 0.862 | 0.831 |
| best | 0.959 | 0.94 | 0.924 | 0.895 | 0.862 | 0.831 | |
| Non-Methyl HT-SELEX, 5 experiments | median | 0.997 | 0.996 | 0.988 | 0.982 | 0.96 | 0.949 |
| best | 1.0 | 0.999 | 0.999 | 0.998 | 0.996 | 0.995 | |
| rSNP benchmarking, ADASTRA | odds-ratio | -log-Fisher's P | Pearson r | Kendall tau |
|---|---|---|---|---|
| # | 28.632 | 23.366 | 0.287 | 0.253 |
| TF superclass | Basic domains {1} (TFClass) |
| TF class | Basic helix-loop-helix factors (bHLH) {1.2} (TFClass) |
| TF family | bHLH-ZIP {1.2.6} (TFClass) |
| TF subfamily | MYC {1.2.6.5} (TFClass) |
| TFClass ID | TFClass: 1.2.6.5.5 |
| HGNC | HGNC:6913 |
| MGI | MGI:96921 |
| EntrezGene (human) | GeneID:4149 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:17187 (SSTAR profile) |
| UniProt ID (human) | MAX_HUMAN |
| UniProt ID (mouse) | MAX_MOUSE |
| UniProt AC (human) | P61244 (TFClass) |
| UniProt AC (mouse) | P28574 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 39 human, 6 mouse |
| HT-SELEX | 5 |
| Methyl-HT-SELEX | 1 |
| PCM | MAX.H12INVIVO.2.S.C.pcm |
| PWM | MAX.H12INVIVO.2.S.C.pwm |
| PFM | MAX.H12INVIVO.2.S.C.pfm |
| Alignment | MAX.H12INVIVO.2.S.C.words.tsv |
| Threshold to P-value map | MAX.H12INVIVO.2.S.C.thr |
| Motif in other formats | |
| JASPAR format | MAX.H12INVIVO.2.S.C_jaspar_format.txt |
| MEME format | MAX.H12INVIVO.2.S.C_meme_format.meme |
| Transfac format | MAX.H12INVIVO.2.S.C_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 73.25 | 68.25 | 74.25 | 51.25 |
| 02 | 40.0 | 127.0 | 54.0 | 46.0 |
| 03 | 70.0 | 165.0 | 21.0 | 11.0 |
| 04 | 168.0 | 54.0 | 34.0 | 11.0 |
| 05 | 3.0 | 185.0 | 62.0 | 17.0 |
| 06 | 9.0 | 9.0 | 195.0 | 54.0 |
| 07 | 9.0 | 31.0 | 46.0 | 181.0 |
| 08 | 10.0 | 17.0 | 208.0 | 32.0 |
| 09 | 60.0 | 86.0 | 53.0 | 68.0 |
| 10 | 70.0 | 50.0 | 40.0 | 107.0 |
| 11 | 112.0 | 42.0 | 33.0 | 80.0 |
| 12 | 115.0 | 45.0 | 59.0 | 48.0 |
| 13 | 14.0 | 149.0 | 68.0 | 36.0 |
| 14 | 0.0 | 267.0 | 0.0 | 0.0 |
| 15 | 267.0 | 0.0 | 0.0 | 0.0 |
| 16 | 0.0 | 267.0 | 0.0 | 0.0 |
| 17 | 0.0 | 0.0 | 267.0 | 0.0 |
| 18 | 0.0 | 1.0 | 0.0 | 266.0 |
| 19 | 0.0 | 0.0 | 266.0 | 1.0 |
| 20 | 59.0 | 77.0 | 108.0 | 23.0 |
| 21 | 29.0 | 55.0 | 31.0 | 152.0 |
| 22 | 59.0 | 77.0 | 37.0 | 94.0 |
| 23 | 60.0 | 92.0 | 47.0 | 68.0 |
| 24 | 63.25 | 103.25 | 48.25 | 52.25 |
| 25 | 59.5 | 85.5 | 60.5 | 61.5 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.274 | 0.256 | 0.278 | 0.192 |
| 02 | 0.15 | 0.476 | 0.202 | 0.172 |
| 03 | 0.262 | 0.618 | 0.079 | 0.041 |
| 04 | 0.629 | 0.202 | 0.127 | 0.041 |
| 05 | 0.011 | 0.693 | 0.232 | 0.064 |
| 06 | 0.034 | 0.034 | 0.73 | 0.202 |
| 07 | 0.034 | 0.116 | 0.172 | 0.678 |
| 08 | 0.037 | 0.064 | 0.779 | 0.12 |
| 09 | 0.225 | 0.322 | 0.199 | 0.255 |
| 10 | 0.262 | 0.187 | 0.15 | 0.401 |
| 11 | 0.419 | 0.157 | 0.124 | 0.3 |
| 12 | 0.431 | 0.169 | 0.221 | 0.18 |
| 13 | 0.052 | 0.558 | 0.255 | 0.135 |
| 14 | 0.0 | 1.0 | 0.0 | 0.0 |
| 15 | 1.0 | 0.0 | 0.0 | 0.0 |
| 16 | 0.0 | 1.0 | 0.0 | 0.0 |
| 17 | 0.0 | 0.0 | 1.0 | 0.0 |
| 18 | 0.0 | 0.004 | 0.0 | 0.996 |
| 19 | 0.0 | 0.0 | 0.996 | 0.004 |
| 20 | 0.221 | 0.288 | 0.404 | 0.086 |
| 21 | 0.109 | 0.206 | 0.116 | 0.569 |
| 22 | 0.221 | 0.288 | 0.139 | 0.352 |
| 23 | 0.225 | 0.345 | 0.176 | 0.255 |
| 24 | 0.237 | 0.387 | 0.181 | 0.196 |
| 25 | 0.223 | 0.32 | 0.227 | 0.23 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.091 | 0.022 | 0.104 | -0.258 |
| 02 | -0.498 | 0.633 | -0.207 | -0.363 |
| 03 | 0.047 | 0.893 | -1.113 | -1.704 |
| 04 | 0.911 | -0.207 | -0.655 | -1.704 |
| 05 | -2.741 | 1.006 | -0.072 | -1.309 |
| 06 | -1.88 | -1.88 | 1.058 | -0.207 |
| 07 | -1.88 | -0.744 | -0.363 | 0.985 |
| 08 | -1.788 | -1.309 | 1.123 | -0.713 |
| 09 | -0.104 | 0.249 | -0.225 | 0.018 |
| 10 | 0.047 | -0.282 | -0.498 | 0.464 |
| 11 | 0.509 | -0.451 | -0.684 | 0.178 |
| 12 | 0.535 | -0.384 | -0.121 | -0.322 |
| 13 | -1.488 | 0.792 | 0.018 | -0.6 |
| 14 | -3.887 | 1.371 | -3.887 | -3.887 |
| 15 | 1.371 | -3.887 | -3.887 | -3.887 |
| 16 | -3.887 | 1.371 | -3.887 | -3.887 |
| 17 | -3.887 | -3.887 | 1.371 | -3.887 |
| 18 | -3.887 | -3.348 | -3.887 | 1.367 |
| 19 | -3.887 | -3.887 | 1.367 | -3.348 |
| 20 | -0.121 | 0.14 | 0.473 | -1.027 |
| 21 | -0.807 | -0.189 | -0.744 | 0.811 |
| 22 | -0.121 | 0.14 | -0.574 | 0.336 |
| 23 | -0.104 | 0.315 | -0.342 | 0.018 |
| 24 | -0.053 | 0.429 | -0.317 | -0.239 |
| 25 | -0.112 | 0.243 | -0.096 | -0.08 |
| P-value | Threshold |
|---|---|
| 0.001 | 1.49111 |
| 0.0005 | 2.86351 |
| 0.0001 | 5.73281 |