MotifMAX.H12INVIVO.1.M.C
Gene (human)MAX
(GeneCards)
Gene synonyms (human)BHLHD4
Gene (mouse)Max
Gene synonyms (mouse)Myn
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
C
Motif length14
ConsensusnnvvCATGTGvbhn
GC content48.7%
Information content (bits; total / per base)12.384 / 0.885
Data sourcesMethyl-HT-SELEX
Aligned words6199

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 39 (261) 0.836 0.919 0.653 0.769 0.771 0.9 2.076 2.871 105.155 415.187
Mouse 6 (39) 0.814 0.886 0.626 0.717 0.765 0.868 2.263 2.674 136.167 332.658

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 6 experiments median 0.981 0.963 0.978 0.96 0.948 0.929
best 0.988 0.976 0.989 0.977 0.983 0.969
Methyl HT-SELEX, 1 experiments median 0.974 0.956 0.964 0.941 0.936 0.91
best 0.974 0.956 0.964 0.941 0.936 0.91
Non-Methyl HT-SELEX, 5 experiments median 0.981 0.966 0.978 0.961 0.96 0.931
best 0.988 0.976 0.989 0.977 0.983 0.969

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 4.178 7.511 0.237 0.155
TF superclassBasic domains {1} (TFClass)
TF classBasic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF familybHLH-ZIP {1.2.6} (TFClass)
TF subfamilyMYC {1.2.6.5} (TFClass)
TFClass IDTFClass: 1.2.6.5.5
HGNCHGNC:6913
MGIMGI:96921
EntrezGene (human)GeneID:4149
(SSTAR profile)
EntrezGene (mouse)GeneID:17187
(SSTAR profile)
UniProt ID (human)MAX_HUMAN
UniProt ID (mouse)MAX_MOUSE
UniProt AC (human)P61244
(TFClass)
UniProt AC (mouse)P28574
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 39 human, 6 mouse
HT-SELEX 5
Methyl-HT-SELEX 1
PCM
ACGT
011382.51384.51503.51928.5
022003.25865.251321.252009.25
033284.01028.01031.0856.0
041687.02416.01973.0123.0
050.06199.00.00.0
066199.00.00.00.0
070.0611.00.05588.0
080.00.06199.00.0
091.0256.00.05942.0
100.01.06119.079.0
111248.02720.01183.01048.0
12639.01223.0941.03396.0
131605.51624.5768.52200.5
141864.251435.251459.251440.25
PFM
ACGT
010.2230.2230.2430.311
020.3230.140.2130.324
030.530.1660.1660.138
040.2720.390.3180.02
050.01.00.00.0
061.00.00.00.0
070.00.0990.00.901
080.00.01.00.0
090.00.0410.00.959
100.00.00.9870.013
110.2010.4390.1910.169
120.1030.1970.1520.548
130.2590.2620.1240.355
140.3010.2320.2350.232
PWM
ACGT
01-0.114-0.113-0.030.218
020.256-0.582-0.1590.259
030.75-0.41-0.407-0.592
040.0850.4440.241-2.517
05-6.5671.385-6.567-6.567
061.385-6.567-6.567-6.567
07-6.567-0.929-6.5671.282
08-6.567-6.5671.385-6.567
09-6.189-1.794-6.5671.343
10-6.567-6.1891.372-2.951
11-0.2160.562-0.27-0.391
12-0.884-0.236-0.4980.784
130.0350.047-0.70.35
140.185-0.077-0.06-0.073
Standard thresholds
P-value Threshold
0.001 2.39071
0.0005 4.61256
0.0001 7.730115