MAX.H12INVIVO.0.PS.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MAX.H12INVIVO.0.PS.A
Gene (human)	MAX (GeneCards)
Gene synonyms (human)	BHLHD4
Gene (mouse)	Max
Gene synonyms (mouse)	Myn
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	11
Consensus	vvvCACGYGSh
GC content	67.78%
Information content (bits; total / per base)	10.727 / 0.975
Data sources	ChIP-Seq + HT-SELEX
Aligned words	999

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	39 (261)	0.898	0.969	0.817	0.928	0.838	0.937	2.882	3.687	279.959	647.481
Mouse	6 (39)	0.883	0.939	0.789	0.884	0.823	0.885	2.696	3.239	215.509	511.495

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 6 experiments	median	0.99	0.981	0.986	0.977	0.959	0.951
Overall, 6 experiments	best	0.998	0.996	0.996	0.993	0.991	0.984
Methyl HT-SELEX, 1 experiments	median	0.941	0.898	0.929	0.884	0.898	0.853
Methyl HT-SELEX, 1 experiments	best	0.941	0.898	0.929	0.884	0.898	0.853
Non-Methyl HT-SELEX, 5 experiments	median	0.994	0.988	0.988	0.982	0.966	0.953
Non-Methyl HT-SELEX, 5 experiments	best	0.998	0.996	0.996	0.993	0.991	0.984

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	19.954	22.219	0.278	0.25

TF superclass	Basic domains {1} (TFClass)
TF class	Basic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF family	bHLH-ZIP {1.2.6} (TFClass)
TF subfamily	MYC {1.2.6.5} (TFClass)
TFClass ID	TFClass: 1.2.6.5.5
HGNC	HGNC:6913
MGI	MGI:96921
EntrezGene (human)	GeneID:4149 (SSTAR profile)
EntrezGene (mouse)	GeneID:17187 (SSTAR profile)
UniProt ID (human)	MAX_HUMAN
UniProt ID (mouse)	MAX_MOUSE
UniProt AC (human)	P61244 (TFClass)
UniProt AC (mouse)	P28574 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	39 human, 6 mouse
HT-SELEX	5
Methyl-HT-SELEX	1

PCM	MAX.H12INVIVO.0.PS.A.pcm
PWM	MAX.H12INVIVO.0.PS.A.pwm
PFM	MAX.H12INVIVO.0.PS.A.pfm
Alignment	MAX.H12INVIVO.0.PS.A.words.tsv
Threshold to P-value map	MAX.H12INVIVO.0.PS.A.thr
Motif in other formats
JASPAR format	MAX.H12INVIVO.0.PS.A_jaspar_format.txt
MEME format	MAX.H12INVIVO.0.PS.A_meme_format.meme
Transfac format	MAX.H12INVIVO.0.PS.A_transfac_format.txt
Homer format	MAX.H12INVIVO.0.PS.A_homer_format_0.001.txt MAX.H12INVIVO.0.PS.A_homer_format_0.0005.txt MAX.H12INVIVO.0.PS.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	194.0	242.0	496.0	67.0
02	355.0	314.0	235.0	95.0
03	151.0	191.0	581.0	76.0
04	32.0	962.0	5.0	0.0
05	969.0	2.0	18.0	10.0
06	1.0	913.0	29.0	56.0
07	102.0	8.0	880.0	9.0
08	99.0	150.0	3.0	747.0
09	6.0	5.0	969.0	19.0
10	88.0	107.0	719.0	85.0
11	177.0	449.0	170.0	203.0

PFM

	A	C	G	T
01	0.194	0.242	0.496	0.067
02	0.355	0.314	0.235	0.095
03	0.151	0.191	0.582	0.076
04	0.032	0.963	0.005	0.0
05	0.97	0.002	0.018	0.01
06	0.001	0.914	0.029	0.056
07	0.102	0.008	0.881	0.009
08	0.099	0.15	0.003	0.748
09	0.006	0.005	0.97	0.019
10	0.088	0.107	0.72	0.085
11	0.177	0.449	0.17	0.203

PWM

	A	C	G	T
01	-0.251	-0.031	0.683	-1.297
02	0.35	0.228	-0.06	-0.955
03	-0.499	-0.266	0.84	-1.174
04	-2.009	1.343	-3.621	-4.981
05	1.351	-4.212	-2.545	-3.065
06	-4.524	1.291	-2.102	-1.472
07	-0.886	-3.252	1.255	-3.155
08	-0.915	-0.505	-3.974	1.091
09	-3.483	-3.621	1.351	-2.496
10	-1.031	-0.839	1.053	-1.065
11	-0.341	0.584	-0.381	-0.206

Standard thresholds

P-value	Threshold
0.001	4.554185
0.0005	5.509065
0.0001	7.36079