MAX.H12CORE.0.PS.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MAX.H12CORE.0.PS.A
Gene (human)	MAX (GeneCards)
Gene synonyms (human)	BHLHD4
Gene (mouse)	Max
Gene synonyms (mouse)	Myn
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	11
Consensus	ndRbCACGTGn
GC content	56.89%
Information content (bits; total / per base)	11.745 / 1.068
Data sources	ChIP-Seq + HT-SELEX
Aligned words	9832

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	39 (261)	0.872	0.971	0.785	0.935	0.818	0.944	2.729	3.997	222.602	647.387
Mouse	6 (39)	0.857	0.936	0.757	0.897	0.803	0.906	2.601	3.755	184.699	516.602

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 6 experiments	median	0.993	0.989	0.99	0.984	0.967	0.96
Overall, 6 experiments	best	0.999	0.998	0.998	0.996	0.994	0.99
Methyl HT-SELEX, 1 experiments	median	0.946	0.911	0.925	0.884	0.894	0.85
Methyl HT-SELEX, 1 experiments	best	0.946	0.911	0.925	0.884	0.894	0.85
Non-Methyl HT-SELEX, 5 experiments	median	0.996	0.993	0.991	0.987	0.969	0.965
Non-Methyl HT-SELEX, 5 experiments	best	0.999	0.998	0.998	0.996	0.994	0.99

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	27.829	22.986	0.314	0.258

TF superclass	Basic domains {1} (TFClass)
TF class	Basic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF family	bHLH-ZIP {1.2.6} (TFClass)
TF subfamily	MYC {1.2.6.5} (TFClass)
TFClass ID	TFClass: 1.2.6.5.5
HGNC	HGNC:6913
MGI	MGI:96921
EntrezGene (human)	GeneID:4149 (SSTAR profile)
EntrezGene (mouse)	GeneID:17187 (SSTAR profile)
UniProt ID (human)	MAX_HUMAN
UniProt ID (mouse)	MAX_MOUSE
UniProt AC (human)	P61244 (TFClass)
UniProt AC (mouse)	P28574 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	39 human, 6 mouse
HT-SELEX	5
Methyl-HT-SELEX	1

PCM	MAX.H12CORE.0.PS.A.pcm
PWM	MAX.H12CORE.0.PS.A.pwm
PFM	MAX.H12CORE.0.PS.A.pfm
Alignment	MAX.H12CORE.0.PS.A.words.tsv
Threshold to P-value map	MAX.H12CORE.0.PS.A.thr
Motif in other formats
JASPAR format	MAX.H12CORE.0.PS.A_jaspar_format.txt
MEME format	MAX.H12CORE.0.PS.A_meme_format.meme
Transfac format	MAX.H12CORE.0.PS.A_transfac_format.txt
Homer format	MAX.H12CORE.0.PS.A_homer_format_0.001.txt MAX.H12CORE.0.PS.A_homer_format_0.0005.txt MAX.H12CORE.0.PS.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2468.0	2041.0	2445.0	2878.0
02	3528.0	1153.0	2219.0	2932.0
03	5997.0	243.0	2539.0	1053.0
04	989.0	3391.0	3597.0	1855.0
05	0.0	9832.0	0.0	0.0
06	9832.0	0.0	0.0	0.0
07	0.0	9547.0	0.0	285.0
08	1.0	0.0	9831.0	0.0
09	73.0	555.0	0.0	9204.0
10	93.75	106.75	8906.75	724.75
11	2429.0	2310.0	2812.0	2281.0

PFM

	A	C	G	T
01	0.251	0.208	0.249	0.293
02	0.359	0.117	0.226	0.298
03	0.61	0.025	0.258	0.107
04	0.101	0.345	0.366	0.189
05	0.0	1.0	0.0	0.0
06	1.0	0.0	0.0	0.0
07	0.0	0.971	0.0	0.029
08	0.0	0.0	1.0	0.0
09	0.007	0.056	0.0	0.936
10	0.01	0.011	0.906	0.074
11	0.247	0.235	0.286	0.232

PWM

	A	C	G	T
01	0.004	-0.186	-0.005	0.158
02	0.361	-0.756	-0.102	0.176
03	0.891	-2.306	0.032	-0.846
04	-0.909	0.322	0.38	-0.281
05	-6.976	1.386	-6.976	-6.976
06	1.386	-6.976	-6.976	-6.976
07	-6.976	1.356	-6.976	-2.148
08	-6.615	-6.976	1.385	-6.976
09	-3.487	-1.485	-6.976	1.32
10	-3.243	-3.116	1.287	-1.219
11	-0.012	-0.062	0.134	-0.075

Standard thresholds

P-value	Threshold
0.001	3.67894
0.0005	5.12072
0.0001	7.809175