MAFK.H12RSNP.2.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MAFK.H12RSNP.2.S.B
Gene (human)	MAFK (GeneCards)
Gene synonyms (human)
Gene (mouse)	Mafk
Gene synonyms (mouse)	Nfe2u
LOGO
LOGO (reverse complement)
Motif subtype	2
Quality	B

Motif length	12
Consensus	ndnYGCTGAbdn
GC content	50.32%
Information content (bits; total / per base)	11.612 / 0.968
Data sources	HT-SELEX
Aligned words	840

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	7 (47)	0.928	0.951	0.89	0.929	0.923	0.946	4.093	4.491	690.585	1024.0
Mouse	10 (62)	0.908	0.961	0.886	0.939	0.902	0.955	4.065	4.614	362.56	697.036

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 4 experiments	median	0.81	0.802	0.731	0.729	0.632	0.647
Non-Methyl HT-SELEX, 4 experiments	best	0.998	0.997	0.995	0.993	0.946	0.945

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	6.372	20.106	0.389	0.227

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Maf-related {1.1.3} (TFClass)
TF subfamily	Small MAF {1.1.3.2} (TFClass)
TFClass ID	TFClass: 1.1.3.2.3
HGNC	HGNC:6782
MGI	MGI:99951
EntrezGene (human)	GeneID:7975 (SSTAR profile)
EntrezGene (mouse)	GeneID:17135 (SSTAR profile)
UniProt ID (human)	MAFK_HUMAN
UniProt ID (mouse)	MAFK_MOUSE
UniProt AC (human)	O60675 (TFClass)
UniProt AC (mouse)	Q61827 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	7 human, 10 mouse
HT-SELEX	4
Methyl-HT-SELEX	0

PCM	MAFK.H12RSNP.2.S.B.pcm
PWM	MAFK.H12RSNP.2.S.B.pwm
PFM	MAFK.H12RSNP.2.S.B.pfm
Alignment	MAFK.H12RSNP.2.S.B.words.tsv
Threshold to P-value map	MAFK.H12RSNP.2.S.B.thr
Motif in other formats
JASPAR format	MAFK.H12RSNP.2.S.B_jaspar_format.txt
MEME format	MAFK.H12RSNP.2.S.B_meme_format.meme
Transfac format	MAFK.H12RSNP.2.S.B_transfac_format.txt
Homer format	MAFK.H12RSNP.2.S.B_homer_format_0.001.txt MAFK.H12RSNP.2.S.B_homer_format_0.0005.txt MAFK.H12RSNP.2.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	313.0	133.0	162.0	232.0
02	299.5	104.5	156.5	279.5
03	274.0	173.0	197.0	196.0
04	38.0	174.0	25.0	603.0
05	1.0	5.0	834.0	0.0
06	0.0	840.0	0.0	0.0
07	0.0	0.0	0.0	840.0
08	0.0	0.0	840.0	0.0
09	837.0	1.0	2.0	0.0
10	30.0	441.0	241.0	128.0
11	132.25	80.25	228.25	399.25
12	194.5	266.5	168.5	210.5

PFM

	A	C	G	T
01	0.373	0.158	0.193	0.276
02	0.357	0.124	0.186	0.333
03	0.326	0.206	0.235	0.233
04	0.045	0.207	0.03	0.718
05	0.001	0.006	0.993	0.0
06	0.0	1.0	0.0	0.0
07	0.0	0.0	0.0	1.0
08	0.0	0.0	1.0	0.0
09	0.996	0.001	0.002	0.0
10	0.036	0.525	0.287	0.152
11	0.157	0.096	0.272	0.475
12	0.232	0.317	0.201	0.251

PWM

	A	C	G	T
01	0.396	-0.452	-0.257	0.099
02	0.353	-0.69	-0.291	0.284
03	0.264	-0.192	-0.063	-0.068
04	-1.674	-0.186	-2.071	1.05
05	-4.368	-3.455	1.373	-4.834
06	-4.834	1.38	-4.834	-4.834
07	-4.834	-4.834	-4.834	1.38
08	-4.834	-4.834	1.38	-4.834
09	1.377	-4.368	-4.051	-4.834
10	-1.899	0.738	0.137	-0.49
11	-0.458	-0.949	0.083	0.639
12	-0.076	0.237	-0.218	0.002

Standard thresholds

P-value	Threshold
0.001	3.444985
0.0005	5.35307
0.0001	7.839415