MAFK.H12RSNP.0.PS.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MAFK.H12RSNP.0.PS.A
Gene (human)	MAFK (GeneCards)
Gene synonyms (human)
Gene (mouse)	Mafk
Gene synonyms (mouse)	Nfe2u
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	18
Consensus	ddWWnTGCTGASWYRKSW
GC content	42.96%
Information content (bits; total / per base)	17.757 / 0.986
Data sources	ChIP-Seq + HT-SELEX
Aligned words	826

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	7 (47)	0.962	0.986	0.946	0.98	0.955	0.982	6.135	7.467	856.585	1171.886
Mouse	10 (62)	0.937	0.981	0.928	0.972	0.935	0.975	6.508	7.95	420.005	748.959

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 4 experiments	median	0.818	0.819	0.746	0.752	0.638	0.66
Non-Methyl HT-SELEX, 4 experiments	best	1.0	1.0	0.999	0.999	0.965	0.966

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	13.569	33.549	0.428	0.305

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Maf-related {1.1.3} (TFClass)
TF subfamily	Small MAF {1.1.3.2} (TFClass)
TFClass ID	TFClass: 1.1.3.2.3
HGNC	HGNC:6782
MGI	MGI:99951
EntrezGene (human)	GeneID:7975 (SSTAR profile)
EntrezGene (mouse)	GeneID:17135 (SSTAR profile)
UniProt ID (human)	MAFK_HUMAN
UniProt ID (mouse)	MAFK_MOUSE
UniProt AC (human)	O60675 (TFClass)
UniProt AC (mouse)	Q61827 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	7 human, 10 mouse
HT-SELEX	4
Methyl-HT-SELEX	0

PCM	MAFK.H12RSNP.0.PS.A.pcm
PWM	MAFK.H12RSNP.0.PS.A.pwm
PFM	MAFK.H12RSNP.0.PS.A.pfm
Alignment	MAFK.H12RSNP.0.PS.A.words.tsv
Threshold to P-value map	MAFK.H12RSNP.0.PS.A.thr
Motif in other formats
JASPAR format	MAFK.H12RSNP.0.PS.A_jaspar_format.txt
MEME format	MAFK.H12RSNP.0.PS.A_meme_format.meme
Transfac format	MAFK.H12RSNP.0.PS.A_transfac_format.txt
Homer format	MAFK.H12RSNP.0.PS.A_homer_format_0.001.txt MAFK.H12RSNP.0.PS.A_homer_format_0.0005.txt MAFK.H12RSNP.0.PS.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	364.0	94.0	192.0	176.0
02	405.0	37.0	148.0	236.0
03	497.0	18.0	41.0	270.0
04	406.0	49.0	35.0	336.0
05	226.0	173.0	133.0	294.0
06	28.0	25.0	1.0	772.0
07	1.0	0.0	825.0	0.0
08	54.0	772.0	0.0	0.0
09	5.0	1.0	0.0	820.0
10	0.0	0.0	810.0	16.0
11	819.0	1.0	2.0	4.0
12	30.0	421.0	308.0	67.0
13	87.0	59.0	31.0	649.0
14	101.0	548.0	44.0	133.0
15	607.0	4.0	115.0	100.0
16	65.0	23.0	546.0	192.0
17	20.0	640.0	119.0	47.0
18	536.0	88.0	85.0	117.0

PFM

	A	C	G	T
01	0.441	0.114	0.232	0.213
02	0.49	0.045	0.179	0.286
03	0.602	0.022	0.05	0.327
04	0.492	0.059	0.042	0.407
05	0.274	0.209	0.161	0.356
06	0.034	0.03	0.001	0.935
07	0.001	0.0	0.999	0.0
08	0.065	0.935	0.0	0.0
09	0.006	0.001	0.0	0.993
10	0.0	0.0	0.981	0.019
11	0.992	0.001	0.002	0.005
12	0.036	0.51	0.373	0.081
13	0.105	0.071	0.038	0.786
14	0.122	0.663	0.053	0.161
15	0.735	0.005	0.139	0.121
16	0.079	0.028	0.661	0.232
17	0.024	0.775	0.144	0.057
18	0.649	0.107	0.103	0.142

PWM

	A	C	G	T
01	0.563	-0.777	-0.072	-0.158
02	0.67	-1.683	-0.33	0.133
03	0.874	-2.359	-1.585	0.266
04	0.672	-1.413	-1.736	0.484
05	0.09	-0.175	-0.436	0.351
06	-1.948	-2.055	-4.353	1.313
07	-4.353	-4.82	1.379	-4.82
08	-1.319	1.313	-4.82	-4.82
09	-3.439	-4.353	-4.82	1.373
10	-4.82	-4.82	1.361	-2.466
11	1.372	-4.353	-4.036	-3.602
12	-1.883	0.708	0.397	-1.109
13	-0.853	-1.233	-1.852	1.14
14	-0.707	0.971	-1.517	-0.436
15	1.073	-3.602	-0.579	-0.717
16	-1.139	-2.132	0.967	-0.072
17	-2.262	1.126	-0.545	-1.453
18	0.949	-0.842	-0.876	-0.562

Standard thresholds

P-value	Threshold
0.001	1.32371
0.0005	2.72471
0.0001	5.64831