MAFK.H12INVIVO.2.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MAFK.H12INVIVO.2.S.B
Gene (human)	MAFK (GeneCards)
Gene synonyms (human)
Gene (mouse)	Mafk
Gene synonyms (mouse)	Nfe2u
LOGO
LOGO (reverse complement)
Motif subtype	2
Quality	B

Motif length	12
Consensus	nddYGCTGAbdn
GC content	49.76%
Information content (bits; total / per base)	11.611 / 0.968
Data sources	HT-SELEX
Aligned words	921

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	7 (47)	0.929	0.951	0.892	0.93	0.922	0.945	4.116	4.517	715.222	1032.62
Mouse	10 (62)	0.91	0.962	0.886	0.942	0.903	0.955	4.078	4.636	366.115	716.337

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 4 experiments	median	0.814	0.805	0.735	0.733	0.637	0.65
Non-Methyl HT-SELEX, 4 experiments	best	0.998	0.997	0.995	0.993	0.946	0.946

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	5.359	17.532	0.392	0.219

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Maf-related {1.1.3} (TFClass)
TF subfamily	Small MAF {1.1.3.2} (TFClass)
TFClass ID	TFClass: 1.1.3.2.3
HGNC	HGNC:6782
MGI	MGI:99951
EntrezGene (human)	GeneID:7975 (SSTAR profile)
EntrezGene (mouse)	GeneID:17135 (SSTAR profile)
UniProt ID (human)	MAFK_HUMAN
UniProt ID (mouse)	MAFK_MOUSE
UniProt AC (human)	O60675 (TFClass)
UniProt AC (mouse)	Q61827 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	7 human, 10 mouse
HT-SELEX	4
Methyl-HT-SELEX	0

PCM	MAFK.H12INVIVO.2.S.B.pcm
PWM	MAFK.H12INVIVO.2.S.B.pwm
PFM	MAFK.H12INVIVO.2.S.B.pfm
Alignment	MAFK.H12INVIVO.2.S.B.words.tsv
Threshold to P-value map	MAFK.H12INVIVO.2.S.B.thr
Motif in other formats
JASPAR format	MAFK.H12INVIVO.2.S.B_jaspar_format.txt
MEME format	MAFK.H12INVIVO.2.S.B_meme_format.meme
Transfac format	MAFK.H12INVIVO.2.S.B_transfac_format.txt
Homer format	MAFK.H12INVIVO.2.S.B_homer_format_0.001.txt MAFK.H12INVIVO.2.S.B_homer_format_0.0005.txt MAFK.H12INVIVO.2.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	327.5	129.5	207.5	256.5
02	335.25	124.25	166.25	295.25
03	370.0	136.0	210.0	205.0
04	35.0	188.0	18.0	680.0
05	3.0	1.0	917.0	0.0
06	0.0	921.0	0.0	0.0
07	0.0	0.0	1.0	920.0
08	0.0	0.0	921.0	0.0
09	912.0	5.0	3.0	1.0
10	62.0	430.0	296.0	133.0
11	129.0	108.0	237.0	447.0
12	216.25	315.25	164.25	225.25

PFM

	A	C	G	T
01	0.356	0.141	0.225	0.279
02	0.364	0.135	0.181	0.321
03	0.402	0.148	0.228	0.223
04	0.038	0.204	0.02	0.738
05	0.003	0.001	0.996	0.0
06	0.0	1.0	0.0	0.0
07	0.0	0.0	0.001	0.999
08	0.0	0.0	1.0	0.0
09	0.99	0.005	0.003	0.001
10	0.067	0.467	0.321	0.144
11	0.14	0.117	0.257	0.485
12	0.235	0.342	0.178	0.245

PWM

	A	C	G	T
01	0.35	-0.57	-0.103	0.107
02	0.373	-0.611	-0.323	0.247
03	0.472	-0.521	-0.091	-0.115
04	-1.844	-0.201	-2.466	1.078
05	-3.898	-4.451	1.376	-4.912
06	-4.912	1.381	-4.912	-4.912
07	-4.912	-4.912	-4.451	1.38
08	-4.912	-4.912	1.381	-4.912
09	1.371	-3.543	-3.898	-4.451
10	-1.292	0.621	0.25	-0.543
11	-0.574	-0.749	0.029	0.66
12	-0.062	0.312	-0.335	-0.022

Standard thresholds

P-value	Threshold
0.001	3.47927
0.0005	5.27934
0.0001	7.828385