MAFK.H12INVIVO.0.PS.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MAFK.H12INVIVO.0.PS.A
Gene (human)	MAFK (GeneCards)
Gene synonyms (human)
Gene (mouse)	Mafk
Gene synonyms (mouse)	Nfe2u
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	20
Consensus	nddWWdYGCTGASKYMRSvn
GC content	45.95%
Information content (bits; total / per base)	14.701 / 0.735
Data sources	ChIP-Seq + HT-SELEX
Aligned words	9832

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	7 (47)	0.969	0.99	0.951	0.983	0.965	0.989	5.809	7.12	865.301	1223.301
Mouse	10 (62)	0.943	0.985	0.935	0.976	0.941	0.979	6.205	7.569	417.159	742.337

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 4 experiments	median	0.825	0.824	0.725	0.732	0.618	0.642
Non-Methyl HT-SELEX, 4 experiments	best	1.0	1.0	0.999	0.999	0.927	0.935

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	9.297	28.334	0.423	0.292

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Maf-related {1.1.3} (TFClass)
TF subfamily	Small MAF {1.1.3.2} (TFClass)
TFClass ID	TFClass: 1.1.3.2.3
HGNC	HGNC:6782
MGI	MGI:99951
EntrezGene (human)	GeneID:7975 (SSTAR profile)
EntrezGene (mouse)	GeneID:17135 (SSTAR profile)
UniProt ID (human)	MAFK_HUMAN
UniProt ID (mouse)	MAFK_MOUSE
UniProt AC (human)	O60675 (TFClass)
UniProt AC (mouse)	Q61827 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	7 human, 10 mouse
HT-SELEX	4
Methyl-HT-SELEX	0

PCM	MAFK.H12INVIVO.0.PS.A.pcm
PWM	MAFK.H12INVIVO.0.PS.A.pwm
PFM	MAFK.H12INVIVO.0.PS.A.pfm
Alignment	MAFK.H12INVIVO.0.PS.A.words.tsv
Threshold to P-value map	MAFK.H12INVIVO.0.PS.A.thr
Motif in other formats
JASPAR format	MAFK.H12INVIVO.0.PS.A_jaspar_format.txt
MEME format	MAFK.H12INVIVO.0.PS.A_meme_format.meme
Transfac format	MAFK.H12INVIVO.0.PS.A_transfac_format.txt
Homer format	MAFK.H12INVIVO.0.PS.A_homer_format_0.001.txt MAFK.H12INVIVO.0.PS.A_homer_format_0.0005.txt MAFK.H12INVIVO.0.PS.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	3428.75	2155.75	2283.75	1963.75
02	4435.5	1483.5	1985.5	1927.5
03	5067.0	794.0	1406.0	2565.0
04	4787.0	524.0	757.0	3764.0
05	4347.0	769.0	554.0	4162.0
06	3429.0	1425.0	1574.0	3404.0
07	518.0	1746.0	171.0	7397.0
08	200.0	266.0	9238.0	128.0
09	222.0	9425.0	97.0	88.0
10	122.0	248.0	132.0	9330.0
11	171.0	98.0	9142.0	421.0
12	9435.0	204.0	79.0	114.0
13	378.0	5894.0	2935.0	625.0
14	649.0	444.0	1758.0	6981.0
15	1260.0	6283.0	375.0	1914.0
16	6927.0	1314.0	847.0	744.0
17	1517.0	387.0	7015.0	913.0
18	530.0	6680.0	1882.0	740.0
19	4464.5	2001.5	1959.5	1406.5
20	3021.25	1938.25	2077.25	2795.25

PFM

	A	C	G	T
01	0.349	0.219	0.232	0.2
02	0.451	0.151	0.202	0.196
03	0.515	0.081	0.143	0.261
04	0.487	0.053	0.077	0.383
05	0.442	0.078	0.056	0.423
06	0.349	0.145	0.16	0.346
07	0.053	0.178	0.017	0.752
08	0.02	0.027	0.94	0.013
09	0.023	0.959	0.01	0.009
10	0.012	0.025	0.013	0.949
11	0.017	0.01	0.93	0.043
12	0.96	0.021	0.008	0.012
13	0.038	0.599	0.299	0.064
14	0.066	0.045	0.179	0.71
15	0.128	0.639	0.038	0.195
16	0.705	0.134	0.086	0.076
17	0.154	0.039	0.713	0.093
18	0.054	0.679	0.191	0.075
19	0.454	0.204	0.199	0.143
20	0.307	0.197	0.211	0.284

PWM

	A	C	G	T
01	0.333	-0.131	-0.073	-0.224
02	0.59	-0.504	-0.213	-0.243
03	0.723	-1.128	-0.558	0.043
04	0.666	-1.542	-1.176	0.426
05	0.57	-1.16	-1.487	0.526
06	0.333	-0.544	-0.445	0.325
07	-1.554	-0.342	-2.653	1.101
08	-2.498	-2.216	1.323	-2.938
09	-2.395	1.343	-3.21	-3.305
10	-2.985	-2.285	-2.908	1.333
11	-2.653	-3.2	1.313	-1.76
12	1.344	-2.479	-3.41	-3.052
13	-1.867	0.874	0.177	-1.367
14	-1.329	-1.707	-0.335	1.043
15	-0.667	0.938	-1.875	-0.25
16	1.035	-0.625	-1.064	-1.193
17	-0.482	-1.844	1.048	-0.989
18	-1.531	0.999	-0.267	-1.198
19	0.596	-0.205	-0.226	-0.558
20	0.206	-0.237	-0.168	0.128

Standard thresholds

P-value	Threshold
0.001	3.23086
0.0005	4.32046
0.0001	6.61411