MAFK.H12INVITRO.1.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MAFK.H12INVITRO.1.P.B
Gene (human)	MAFK (GeneCards)
Gene synonyms (human)
Gene (mouse)	Mafk
Gene synonyms (mouse)	Nfe2u
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	12
Consensus	WhTGCTGASTYA
GC content	43.3%
Information content (bits; total / per base)	15.99 / 1.332
Data sources	ChIP-Seq
Aligned words	731

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	7 (47)	0.951	0.976	0.915	0.958	0.932	0.962	4.791	5.363	772.886	1037.523
Mouse	10 (62)	0.924	0.973	0.904	0.957	0.918	0.966	4.861	5.62	389.238	718.495

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 4 experiments	median	0.815	0.806	0.735	0.732	0.633	0.649
Non-Methyl HT-SELEX, 4 experiments	best	0.999	0.998	0.994	0.992	0.95	0.948

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	6.043	20.031	0.399	0.242

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Maf-related {1.1.3} (TFClass)
TF subfamily	Small MAF {1.1.3.2} (TFClass)
TFClass ID	TFClass: 1.1.3.2.3
HGNC	HGNC:6782
MGI	MGI:99951
EntrezGene (human)	GeneID:7975 (SSTAR profile)
EntrezGene (mouse)	GeneID:17135 (SSTAR profile)
UniProt ID (human)	MAFK_HUMAN
UniProt ID (mouse)	MAFK_MOUSE
UniProt AC (human)	O60675 (TFClass)
UniProt AC (mouse)	Q61827 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	7 human, 10 mouse
HT-SELEX	4
Methyl-HT-SELEX	0

PCM	MAFK.H12INVITRO.1.P.B.pcm
PWM	MAFK.H12INVITRO.1.P.B.pwm
PFM	MAFK.H12INVITRO.1.P.B.pfm
Alignment	MAFK.H12INVITRO.1.P.B.words.tsv
Threshold to P-value map	MAFK.H12INVITRO.1.P.B.thr
Motif in other formats
JASPAR format	MAFK.H12INVITRO.1.P.B_jaspar_format.txt
MEME format	MAFK.H12INVITRO.1.P.B_meme_format.meme
Transfac format	MAFK.H12INVITRO.1.P.B_transfac_format.txt
Homer format	MAFK.H12INVITRO.1.P.B_homer_format_0.001.txt MAFK.H12INVITRO.1.P.B_homer_format_0.0005.txt MAFK.H12INVITRO.1.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	342.0	24.0	34.0	331.0
02	203.0	141.0	88.0	299.0
03	10.0	15.0	0.0	706.0
04	0.0	0.0	731.0	0.0
05	22.0	709.0	0.0	0.0
06	0.0	3.0	0.0	728.0
07	0.0	0.0	718.0	13.0
08	727.0	0.0	1.0	3.0
09	24.0	399.0	262.0	46.0
10	54.0	26.0	12.0	639.0
11	72.0	553.0	21.0	85.0
12	623.0	10.0	51.0	47.0

PFM

	A	C	G	T
01	0.468	0.033	0.047	0.453
02	0.278	0.193	0.12	0.409
03	0.014	0.021	0.0	0.966
04	0.0	0.0	1.0	0.0
05	0.03	0.97	0.0	0.0
06	0.0	0.004	0.0	0.996
07	0.0	0.0	0.982	0.018
08	0.995	0.0	0.001	0.004
09	0.033	0.546	0.358	0.063
10	0.074	0.036	0.016	0.874
11	0.098	0.756	0.029	0.116
12	0.852	0.014	0.07	0.064

PWM

	A	C	G	T
01	0.623	-1.973	-1.643	0.59
02	0.104	-0.257	-0.721	0.489
03	-2.762	-2.405	-4.717	1.345
04	-4.717	-4.717	1.38	-4.717
05	-2.054	1.349	-4.717	-4.717
06	-4.717	-3.681	-4.717	1.375
07	-4.717	-4.717	1.362	-2.533
08	1.374	-4.717	-4.243	-3.681
09	-1.973	0.776	0.358	-1.353
10	-1.198	-1.898	-2.603	1.245
11	-0.918	1.101	-2.097	-0.755
12	1.22	-2.762	-1.253	-1.332

Standard thresholds

P-value	Threshold
0.001	1.896915
0.0005	3.27521
0.0001	6.185405