MAFK.H12INVITRO.0.PS.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MAFK.H12INVITRO.0.PS.A
Gene (human)	MAFK (GeneCards)
Gene synonyms (human)
Gene (mouse)	Mafk
Gene synonyms (mouse)	Nfe2u
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	18
Consensus	ddWdnTGCTGASYMRKCW
GC content	46.12%
Information content (bits; total / per base)	17.386 / 0.966
Data sources	ChIP-Seq + HT-SELEX
Aligned words	1000

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	7 (47)	0.957	0.979	0.939	0.973	0.947	0.975	5.946	7.192	854.796	1138.237
Mouse	10 (62)	0.936	0.981	0.926	0.973	0.932	0.975	6.593	7.99	418.006	737.444

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 4 experiments	median	0.826	0.824	0.753	0.756	0.647	0.666
Non-Methyl HT-SELEX, 4 experiments	best	1.0	1.0	1.0	0.999	0.966	0.967

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	11.473	31.389	0.428	0.303

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Maf-related {1.1.3} (TFClass)
TF subfamily	Small MAF {1.1.3.2} (TFClass)
TFClass ID	TFClass: 1.1.3.2.3
HGNC	HGNC:6782
MGI	MGI:99951
EntrezGene (human)	GeneID:7975 (SSTAR profile)
EntrezGene (mouse)	GeneID:17135 (SSTAR profile)
UniProt ID (human)	MAFK_HUMAN
UniProt ID (mouse)	MAFK_MOUSE
UniProt AC (human)	O60675 (TFClass)
UniProt AC (mouse)	Q61827 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	7 human, 10 mouse
HT-SELEX	4
Methyl-HT-SELEX	0

PCM	MAFK.H12INVITRO.0.PS.A.pcm
PWM	MAFK.H12INVITRO.0.PS.A.pwm
PFM	MAFK.H12INVITRO.0.PS.A.pfm
Alignment	MAFK.H12INVITRO.0.PS.A.words.tsv
Threshold to P-value map	MAFK.H12INVITRO.0.PS.A.thr
Motif in other formats
JASPAR format	MAFK.H12INVITRO.0.PS.A_jaspar_format.txt
MEME format	MAFK.H12INVITRO.0.PS.A_meme_format.meme
Transfac format	MAFK.H12INVITRO.0.PS.A_transfac_format.txt
Homer format	MAFK.H12INVITRO.0.PS.A_homer_format_0.001.txt MAFK.H12INVITRO.0.PS.A_homer_format_0.0005.txt MAFK.H12INVITRO.0.PS.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	419.0	140.0	267.0	174.0
02	525.0	72.0	184.0	219.0
03	609.0	23.0	66.0	302.0
04	496.0	70.0	93.0	341.0
05	242.0	292.0	199.0	267.0
06	31.0	49.0	2.0	918.0
07	3.0	3.0	993.0	1.0
08	22.0	972.0	0.0	6.0
09	15.0	17.0	1.0	967.0
10	7.0	3.0	958.0	32.0
11	952.0	9.0	12.0	27.0
12	41.0	372.0	520.0	67.0
13	55.0	92.0	49.0	804.0
14	100.0	732.0	71.0	97.0
15	748.0	19.0	136.0	97.0
16	64.0	32.0	732.0	172.0
17	27.0	830.0	99.0	44.0
18	642.0	98.0	94.0	166.0

PFM

	A	C	G	T
01	0.419	0.14	0.267	0.174
02	0.525	0.072	0.184	0.219
03	0.609	0.023	0.066	0.302
04	0.496	0.07	0.093	0.341
05	0.242	0.292	0.199	0.267
06	0.031	0.049	0.002	0.918
07	0.003	0.003	0.993	0.001
08	0.022	0.972	0.0	0.006
09	0.015	0.017	0.001	0.967
10	0.007	0.003	0.958	0.032
11	0.952	0.009	0.012	0.027
12	0.041	0.372	0.52	0.067
13	0.055	0.092	0.049	0.804
14	0.1	0.732	0.071	0.097
15	0.748	0.019	0.136	0.097
16	0.064	0.032	0.732	0.172
17	0.027	0.83	0.099	0.044
18	0.642	0.098	0.094	0.166

PWM

	A	C	G	T
01	0.514	-0.574	0.065	-0.359
02	0.738	-1.228	-0.304	-0.131
03	0.886	-2.32	-1.313	0.188
04	0.682	-1.255	-0.977	0.309
05	-0.032	0.154	-0.226	0.065
06	-2.04	-1.602	-4.213	1.296
07	-3.975	-3.975	1.374	-4.525
08	-2.362	1.353	-4.982	-3.484
09	-2.711	-2.598	-4.525	1.348
10	-3.362	-3.975	1.338	-2.01
11	1.332	-3.156	-2.909	-2.171
12	-1.774	0.395	0.729	-1.298
13	-1.49	-0.988	-1.602	1.163
14	-0.906	1.07	-1.242	-0.936
15	1.091	-2.497	-0.603	-0.936
16	-1.343	-2.01	1.07	-0.371
17	-2.171	1.195	-0.916	-1.706
18	0.939	-0.926	-0.967	-0.406

Standard thresholds

P-value	Threshold
0.001	1.96181
0.0005	3.22866
0.0001	5.89161