MAFK.H12CORE.2.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MAFK.H12CORE.2.S.B
Gene (human)	MAFK (GeneCards)
Gene synonyms (human)
Gene (mouse)	Mafk
Gene synonyms (mouse)	Nfe2u
LOGO
LOGO (reverse complement)
Motif subtype	2
Quality	B

Motif length	12
Consensus	ndnYGCTGAbdn
GC content	49.09%
Information content (bits; total / per base)	11.34 / 0.945
Data sources	HT-SELEX
Aligned words	2280

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	7 (47)	0.936	0.957	0.897	0.933	0.921	0.946	4.042	4.484	688.036	1034.77
Mouse	10 (62)	0.91	0.962	0.885	0.937	0.899	0.952	3.927	4.432	359.489	694.108

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 4 experiments	median	0.817	0.807	0.741	0.737	0.638	0.653
Non-Methyl HT-SELEX, 4 experiments	best	0.998	0.997	0.996	0.993	0.952	0.951

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	4.888	16.722	0.394	0.223

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Maf-related {1.1.3} (TFClass)
TF subfamily	Small MAF {1.1.3.2} (TFClass)
TFClass ID	TFClass: 1.1.3.2.3
HGNC	HGNC:6782
MGI	MGI:99951
EntrezGene (human)	GeneID:7975 (SSTAR profile)
EntrezGene (mouse)	GeneID:17135 (SSTAR profile)
UniProt ID (human)	MAFK_HUMAN
UniProt ID (mouse)	MAFK_MOUSE
UniProt AC (human)	O60675 (TFClass)
UniProt AC (mouse)	Q61827 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	7 human, 10 mouse
HT-SELEX	4
Methyl-HT-SELEX	0

PCM	MAFK.H12CORE.2.S.B.pcm
PWM	MAFK.H12CORE.2.S.B.pwm
PFM	MAFK.H12CORE.2.S.B.pfm
Alignment	MAFK.H12CORE.2.S.B.words.tsv
Threshold to P-value map	MAFK.H12CORE.2.S.B.thr
Motif in other formats
JASPAR format	MAFK.H12CORE.2.S.B_jaspar_format.txt
MEME format	MAFK.H12CORE.2.S.B_meme_format.meme
Transfac format	MAFK.H12CORE.2.S.B_transfac_format.txt
Homer format	MAFK.H12CORE.2.S.B_homer_format_0.001.txt MAFK.H12CORE.2.S.B_homer_format_0.0005.txt MAFK.H12CORE.2.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	816.0	348.0	455.0	661.0
02	863.0	324.0	399.0	694.0
03	787.0	381.0	531.0	581.0
04	108.0	405.0	106.0	1661.0
05	2.0	15.0	2261.0	2.0
06	0.0	2278.0	1.0	1.0
07	0.0	0.0	0.0	2280.0
08	1.0	0.0	2267.0	12.0
09	2263.0	6.0	7.0	4.0
10	153.0	1191.0	520.0	416.0
11	421.0	304.0	488.0	1067.0
12	533.0	733.0	410.0	604.0

PFM

	A	C	G	T
01	0.358	0.153	0.2	0.29
02	0.379	0.142	0.175	0.304
03	0.345	0.167	0.233	0.255
04	0.047	0.178	0.046	0.729
05	0.001	0.007	0.992	0.001
06	0.0	0.999	0.0	0.0
07	0.0	0.0	0.0	1.0
08	0.0	0.0	0.994	0.005
09	0.993	0.003	0.003	0.002
10	0.067	0.522	0.228	0.182
11	0.185	0.133	0.214	0.468
12	0.234	0.321	0.18	0.265

PWM

	A	C	G	T
01	0.358	-0.491	-0.224	0.148
02	0.414	-0.562	-0.355	0.196
03	0.322	-0.401	-0.071	0.019
04	-1.649	-0.34	-1.668	1.067
05	-4.98	-3.52	1.375	-4.98
06	-5.69	1.383	-5.273	-5.273
07	-5.69	-5.69	-5.69	1.384
08	-5.273	-5.69	1.378	-3.715
09	1.376	-4.278	-4.159	-4.568
10	-1.306	0.735	-0.091	-0.314
11	-0.302	-0.626	-0.155	0.625
12	-0.067	0.251	-0.328	0.058

Standard thresholds

P-value	Threshold
0.001	3.61321
0.0005	5.557235
0.0001	7.804185