MAFK.H12CORE.1.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MAFK.H12CORE.1.P.B
Gene (human)	MAFK (GeneCards)
Gene synonyms (human)
Gene (mouse)	Mafk
Gene synonyms (mouse)	Nfe2u
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	13
Consensus	dhhTGCTGASYYR
GC content	47.52%
Information content (bits; total / per base)	12.703 / 0.977
Data sources	ChIP-Seq
Aligned words	1005

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	7 (47)	0.943	0.969	0.904	0.947	0.921	0.954	4.776	5.558	737.268	954.824
Mouse	10 (62)	0.931	0.974	0.901	0.957	0.928	0.969	5.242	6.25	379.146	718.276

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 4 experiments	median	0.81	0.798	0.731	0.724	0.639	0.648
Non-Methyl HT-SELEX, 4 experiments	best	0.999	0.998	0.994	0.992	0.944	0.941

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	8.803	27.865	0.414	0.269

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Maf-related {1.1.3} (TFClass)
TF subfamily	Small MAF {1.1.3.2} (TFClass)
TFClass ID	TFClass: 1.1.3.2.3
HGNC	HGNC:6782
MGI	MGI:99951
EntrezGene (human)	GeneID:7975 (SSTAR profile)
EntrezGene (mouse)	GeneID:17135 (SSTAR profile)
UniProt ID (human)	MAFK_HUMAN
UniProt ID (mouse)	MAFK_MOUSE
UniProt AC (human)	O60675 (TFClass)
UniProt AC (mouse)	Q61827 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	7 human, 10 mouse
HT-SELEX	4
Methyl-HT-SELEX	0

PCM	MAFK.H12CORE.1.P.B.pcm
PWM	MAFK.H12CORE.1.P.B.pwm
PFM	MAFK.H12CORE.1.P.B.pfm
Alignment	MAFK.H12CORE.1.P.B.words.tsv
Threshold to P-value map	MAFK.H12CORE.1.P.B.thr
Motif in other formats
JASPAR format	MAFK.H12CORE.1.P.B_jaspar_format.txt
MEME format	MAFK.H12CORE.1.P.B_meme_format.meme
Transfac format	MAFK.H12CORE.1.P.B_transfac_format.txt
Homer format	MAFK.H12CORE.1.P.B_homer_format_0.001.txt MAFK.H12CORE.1.P.B_homer_format_0.0005.txt MAFK.H12CORE.1.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	479.0	98.0	107.0	321.0
02	409.0	149.0	136.0	311.0
03	172.0	388.0	167.0	278.0
04	55.0	50.0	17.0	883.0
05	6.0	14.0	977.0	8.0
06	16.0	981.0	3.0	5.0
07	38.0	38.0	5.0	924.0
08	23.0	16.0	923.0	43.0
09	900.0	31.0	24.0	50.0
10	43.0	304.0	608.0	50.0
11	78.0	112.0	59.0	756.0
12	89.0	726.0	93.0	97.0
13	752.0	47.0	135.0	71.0

PFM

	A	C	G	T
01	0.477	0.098	0.106	0.319
02	0.407	0.148	0.135	0.309
03	0.171	0.386	0.166	0.277
04	0.055	0.05	0.017	0.879
05	0.006	0.014	0.972	0.008
06	0.016	0.976	0.003	0.005
07	0.038	0.038	0.005	0.919
08	0.023	0.016	0.918	0.043
09	0.896	0.031	0.024	0.05
10	0.043	0.302	0.605	0.05
11	0.078	0.111	0.059	0.752
12	0.089	0.722	0.093	0.097
13	0.748	0.047	0.134	0.071

PWM

	A	C	G	T
01	0.642	-0.931	-0.844	0.244
02	0.485	-0.518	-0.608	0.212
03	-0.376	0.432	-0.405	0.101
04	-1.495	-1.587	-2.603	1.252
05	-3.488	-2.778	1.353	-3.258
06	-2.658	1.357	-3.98	-3.627
07	-1.851	-1.851	-3.627	1.297
08	-2.325	-2.658	1.296	-1.733
09	1.271	-2.045	-2.286	-1.587
10	-1.733	0.189	0.88	-1.587
11	-1.155	-0.799	-1.427	1.097
12	-1.025	1.057	-0.982	-0.941
13	1.092	-1.647	-0.615	-1.247

Standard thresholds

P-value	Threshold
0.001	3.96981
0.0005	4.96091
0.0001	7.04397