MotifMAFK.H12CORE.0.PS.A
Gene (human)MAFK
(GeneCards)
Gene synonyms (human)
Gene (mouse)Mafk
Gene synonyms (mouse)Nfe2u
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length18
ConsensusddWWnTGCTGASWYRKSW
GC content42.96%
Information content (bits; total / per base)17.757 / 0.986
Data sourcesChIP-Seq + HT-SELEX
Aligned words826

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 7 (47) 0.962 0.986 0.946 0.98 0.955 0.982 6.135 7.467 856.585 1171.886
Mouse 10 (62) 0.937 0.981 0.928 0.972 0.935 0.975 6.508 7.95 420.005 748.959

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Non-Methyl HT-SELEX, 4 experiments median 0.818 0.819 0.746 0.752 0.638 0.66
best 1.0 1.0 0.999 0.999 0.965 0.966

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 13.569 33.549 0.428 0.305
TF superclassBasic domains {1} (TFClass)
TF classBasic leucine zipper factors (bZIP) {1.1} (TFClass)
TF familyMaf-related {1.1.3} (TFClass)
TF subfamilySmall MAF {1.1.3.2} (TFClass)
TFClass IDTFClass: 1.1.3.2.3
HGNCHGNC:6782
MGIMGI:99951
EntrezGene (human)GeneID:7975
(SSTAR profile)
EntrezGene (mouse)GeneID:17135
(SSTAR profile)
UniProt ID (human)MAFK_HUMAN
UniProt ID (mouse)MAFK_MOUSE
UniProt AC (human)O60675
(TFClass)
UniProt AC (mouse)Q61827
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 7 human, 10 mouse
HT-SELEX 4
Methyl-HT-SELEX 0
PCM
ACGT
01364.094.0192.0176.0
02405.037.0148.0236.0
03497.018.041.0270.0
04406.049.035.0336.0
05226.0173.0133.0294.0
0628.025.01.0772.0
071.00.0825.00.0
0854.0772.00.00.0
095.01.00.0820.0
100.00.0810.016.0
11819.01.02.04.0
1230.0421.0308.067.0
1387.059.031.0649.0
14101.0548.044.0133.0
15607.04.0115.0100.0
1665.023.0546.0192.0
1720.0640.0119.047.0
18536.088.085.0117.0
PFM
ACGT
010.4410.1140.2320.213
020.490.0450.1790.286
030.6020.0220.050.327
040.4920.0590.0420.407
050.2740.2090.1610.356
060.0340.030.0010.935
070.0010.00.9990.0
080.0650.9350.00.0
090.0060.0010.00.993
100.00.00.9810.019
110.9920.0010.0020.005
120.0360.510.3730.081
130.1050.0710.0380.786
140.1220.6630.0530.161
150.7350.0050.1390.121
160.0790.0280.6610.232
170.0240.7750.1440.057
180.6490.1070.1030.142
PWM
ACGT
010.563-0.777-0.072-0.158
020.67-1.683-0.330.133
030.874-2.359-1.5850.266
040.672-1.413-1.7360.484
050.09-0.175-0.4360.351
06-1.948-2.055-4.3531.313
07-4.353-4.821.379-4.82
08-1.3191.313-4.82-4.82
09-3.439-4.353-4.821.373
10-4.82-4.821.361-2.466
111.372-4.353-4.036-3.602
12-1.8830.7080.397-1.109
13-0.853-1.233-1.8521.14
14-0.7070.971-1.517-0.436
151.073-3.602-0.579-0.717
16-1.139-2.1320.967-0.072
17-2.2621.126-0.545-1.453
180.949-0.842-0.876-0.562
Standard thresholds
P-value Threshold
0.001 1.32371
0.0005 2.72471
0.0001 5.64831