MAFG.H12RSNP.1.PSM.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MAFG.H12RSNP.1.PSM.A
Gene (human)	MAFG (GeneCards)
Gene synonyms (human)
Gene (mouse)	Mafg
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	A

Motif length	14
Consensus	nddhdTGCTGASKh
GC content	47.94%
Information content (bits; total / per base)	13.808 / 0.986
Data sources	ChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words	318

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	2 (14)	0.852	0.879	0.818	0.851	0.865	0.898	3.418	3.668	276.547	704.0
Mouse	2 (14)	0.961	0.964	0.935	0.937	0.963	0.965	4.432	4.459	643.364	767.796

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 6 experiments	median	0.982	0.97	0.923	0.915	0.819	0.805
Overall, 6 experiments	best	0.993	0.99	0.966	0.958	0.879	0.86
Methyl HT-SELEX, 2 experiments	median	0.972	0.955	0.922	0.9	0.819	0.805
Methyl HT-SELEX, 2 experiments	best	0.985	0.976	0.945	0.931	0.83	0.826
Non-Methyl HT-SELEX, 4 experiments	median	0.985	0.975	0.926	0.915	0.792	0.806
Non-Methyl HT-SELEX, 4 experiments	best	0.993	0.99	0.966	0.958	0.879	0.86

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	7.075	7.104	0.298	0.167

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.88	0.603	0.859	0.564
batch 2	0.658	0.439	0.709	0.504

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Maf-related {1.1.3} (TFClass)
TF subfamily	Small MAF {1.1.3.2} (TFClass)
TFClass ID	TFClass: 1.1.3.2.2
HGNC	HGNC:6781
MGI	MGI:96911
EntrezGene (human)	GeneID:4097 (SSTAR profile)
EntrezGene (mouse)	GeneID:17134 (SSTAR profile)
UniProt ID (human)	MAFG_HUMAN
UniProt ID (mouse)	MAFG_MOUSE
UniProt AC (human)	O15525 (TFClass)
UniProt AC (mouse)	O54790 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 2 mouse
HT-SELEX	4
Methyl-HT-SELEX	2

PCM	MAFG.H12RSNP.1.PSM.A.pcm
PWM	MAFG.H12RSNP.1.PSM.A.pwm
PFM	MAFG.H12RSNP.1.PSM.A.pfm
Alignment	MAFG.H12RSNP.1.PSM.A.words.tsv
Threshold to P-value map	MAFG.H12RSNP.1.PSM.A.thr
Motif in other formats
JASPAR format	MAFG.H12RSNP.1.PSM.A_jaspar_format.txt
MEME format	MAFG.H12RSNP.1.PSM.A_meme_format.meme
Transfac format	MAFG.H12RSNP.1.PSM.A_transfac_format.txt
Homer format	MAFG.H12RSNP.1.PSM.A_homer_format_0.001.txt MAFG.H12RSNP.1.PSM.A_homer_format_0.0005.txt MAFG.H12RSNP.1.PSM.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	62.25	100.25	91.25	64.25
02	126.25	51.25	82.25	58.25
03	131.0	35.0	42.0	110.0
04	108.0	50.0	22.0	138.0
05	128.0	19.0	68.0	103.0
06	0.0	31.0	0.0	287.0
07	0.0	0.0	318.0	0.0
08	0.0	318.0	0.0	0.0
09	0.0	0.0	0.0	318.0
10	0.0	0.0	318.0	0.0
11	318.0	0.0	0.0	0.0
12	4.0	236.0	44.0	34.0
13	27.75	16.75	141.75	131.75
14	58.0	119.0	31.0	110.0

PFM

	A	C	G	T
01	0.196	0.315	0.287	0.202
02	0.397	0.161	0.259	0.183
03	0.412	0.11	0.132	0.346
04	0.34	0.157	0.069	0.434
05	0.403	0.06	0.214	0.324
06	0.0	0.097	0.0	0.903
07	0.0	0.0	1.0	0.0
08	0.0	1.0	0.0	0.0
09	0.0	0.0	0.0	1.0
10	0.0	0.0	1.0	0.0
11	1.0	0.0	0.0	0.0
12	0.013	0.742	0.138	0.107
13	0.087	0.053	0.446	0.414
14	0.182	0.374	0.097	0.346

PWM

	A	C	G	T
01	-0.24	0.228	0.136	-0.209
02	0.456	-0.429	0.033	-0.305
03	0.492	-0.798	-0.622	0.32
04	0.302	-0.453	-1.239	0.544
05	0.47	-1.376	-0.153	0.255
06	-4.029	-0.914	-4.029	1.271
07	-4.029	-4.029	1.373	-4.029
08	-4.029	1.373	-4.029	-4.029
09	-4.029	-4.029	-4.029	1.373
10	-4.029	-4.029	1.373	-4.029
11	1.373	-4.029	-4.029	-4.029
12	-2.7	1.076	-0.577	-0.826
13	-1.02	-1.493	0.57	0.498
14	-0.309	0.397	-0.914	0.32

Standard thresholds

P-value	Threshold
0.001	3.18571
0.0005	4.32651
0.0001	7.164965